ascorbic acid negative response
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I am hypometabolic to begin with, but I was feeling better until I messed with the vit C
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I wonder if this has to do with vitamin E. I’ve taken a high-ish dose of it one of these past weeks. Maybe the vitamin C increased my E levels even more…
In other words:
vitamin C —> vitamin E overload? (or vice versa)
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It could also be some impurities. Dr. Peat talked about lead in ascorbic acid supplements for example. Although I'm not sure a single dose of 300mg would have an immediate effect if it was due to impurities. But who knows, even small amounts of something bad can have a noticeable negative effect. For example, just yesterday I bought one of these milk coffees you find in supermarkets and foolishly didn't read the label. It had some Carrageenan in it and I had digestive upset and bloating for the rest of they day.
Based in your post history I would propose it might be a good idea to stop all supplements for a while and focus on nutritious food and a good lifestyle. Taking new supplements to compensate for the negative effects of the old supplements could send you into an even more negative spiral. Especially Vitamin C is very easy to get from foods.
I've never been a big party attender, but I never went to a party where I didn't probably offend most of the people there by talking about what I was interested in. (Ray Peat)
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I don’t think this was about impurities. I’ve taken like 500mg long before (when I wasn’t taking E) and I didn’t really notice anything. I think I just messed up the balance.
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I don’t know much about vit C & E synergy but there is something there. Basically, I accidentally overdosed on one of them by taking the C
but maybe it isn’t the selenium
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@bioenergetical said in ascorbic acid negative response:
I don’t know much about vit C & E synergy
If you think about synergy, I won't think so; not quite so.
Too much quinones left when taking vit E, K Q10 and so on. The liver can't deal with (to get rid of) => overloaded => feel sick.
Too much vit E is not advised too. No need for 400 UI every day. 2x/wk is OK, when taking a mix toco. Not one kind (alpha). -
@Luke said in ascorbic acid negative response:
Based in your post history I would propose it might be a good idea to stop all supplements for a while
Well seen. I'd stop one week and then get informed about the interaction between e.g. liposoluble vitamins.
I can give a link if interested. -
I haven’t taken vitamin E this week. Last time I took it, it was a high-ish dose (400iu). Felt good, but I knew that any more would’ve been problematic
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I took vitamin D (5,000iu) and it stabilized me for now…
I heard about vitamin D depletion from E
If the C increased my E then this is relevant. This could be a vitamin E overdose in disguise
I understand the well intentions behind the “don’t supplement more” but if I already threw the balance off tremendously, then it will be necessary sometimes… the B1 incident was the same way. Yes, there are risks but if I’m in a desperate situation then sitting idly isn’t going to cut it
But I would appreciate the link
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@bioenergetical said in ascorbic acid negative response:
I would appreciate the link
English Corner: Liposoluble vitamins A D E & K – How much fat do we need to absorb them well?
*) Vitamins A, D, E & K – How much lipids do we need to absorb vitamins A D E?
http://suppversity.blogspot.be/2014/05/vitamin-d-e-k-how-much-and-what-type-of.html
Vitamin A (retinol) + bêta-caroten : 3 to 5 g fat.
Source: A Fat D-Ficiency
http://suppversity.blogspot.be/2011/12/fat-d-ficiency-do-you-really-need-more.html
Vitamin E: 3 g fat but a PUFA-diet exhausts toco- and trienols (latent inflammation).
Vitamin K (K1 and K2): 35 g fat
The quantity of phylloquinone (K1) which enters your blood circulation will be reduced by around 70% if you eat your spinach without a supply of fat (Gijsbers, 1996). The absorption of K2 is 3 times larger with 35 g of lipids in the meal than with 20 g. 6 x less with 8.8 g of FA. (Uematsu et al. 1996). However 18-20g and 12-15g of PUFA are consumed daily by the American man and woman (Kris-Eheton, 2000).
Vitamin D : It is the type of fat that will determine the degree of assimilation.Oil-rich in PUFA inhibit the absorption of 25OHD vitamin.
(Niramitmahapanya et al. 2011). An oil with a ratio MUFA: PUFA > 1, like sunflower or soybeans, is deleterious.
Caution: If you have a high supply of PUFA (omega-3 supplementation or oilseed consumption, with the exception of macadamia nuts which are very rich in MUFA), the blood rate of Vit D and E will often be very low because these 2 vitamins also have an anti-inflammatory action and will therefore be hijacked / diverted from their use as hormones. Details on my forum (in French, but with links in in English):
http://mirzoune-ciboulette.forumactif.org/t1357-vitamines-liposolubles-et-matiere-grasse-ratio#15157
*) Synergy effect with vitamin E
“Vitamin C regenerates vitamin E and vitamin E protects β-carotene, helped in this by polyphenols. In the event of β-carotene supplementation, vitamin C regenerates vitamin E and β-carotene, and β-carotene seems to protect vitamin E without really explaining this phenomenon "(1)
Savings effect
Vitamin E is not just a vitamin. Vitamin C makes it possible to recycle oxidized vitamin E and thus prolong its lifespan. The same goes with glutathione which is thus saved for other more useful functions (detox). Glutathion is our antioxidant master. Vitamin E protects against the deleterious effects of polyunsaturated fatty acids when the latter are in excess. And it is quickly done!- John Libbey Eurotext - Anti-oxydants d’origine alimentaire : diversité, modes d’action anti-oxydante, interactions. Auteur : Claude Louis Léger.
- Daniel Raederstorff et al. Br J Nutr. 2015. doi: 10.1017/S000711451500272X
=> 20 mg Vit E for 10 gr PUFA.
*) Factors that facilitate or counter the absorption of vitamin D3
http://mirzoune-ciboulette.forumactif.org/t1664-absorption-de-la-vitamine-d-insuffisante#20619- A Magnesium intake neither too high nor too low (RDA Mg: 360 and 420 mg depending on the sex f / m) is favorable. An excess of Mg will thwart the absorption of vitamin D3.
- Mono-unsaturated fatty acids facilitate the absorption of vitamin D (olive, avocado, macadamia, for example). Saturated fatty acids (SFA) are probably neutral, at this level. But since these SFA’s contribute to the stability of the membranes, we should take care to have a 50/50 ratio between SFA and MUFA. And as few PUFA as what is necessary for metabolism (1 % = 22 gr. It is already calculated widely. 4 % is the level not to be over. 6 % is deleterious). (Perfect health diet. Jaminet).
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my eyes have been tingling, unsure why
