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    ascorbic acid negative response

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    • B
      bioenergetical
      last edited by bioenergetical

      I wonder if this has to do with vitamin E. I’ve taken a high-ish dose of it one of these past weeks. Maybe the vitamin C increased my E levels even more…

      In other words:

      vitamin C —> vitamin E overload? (or vice versa)

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      • LukeL
        Luke
        last edited by Luke

        It could also be some impurities. Dr. Peat talked about lead in ascorbic acid supplements for example. Although I'm not sure a single dose of 300mg would have an immediate effect if it was due to impurities. But who knows, even small amounts of something bad can have a noticeable negative effect. For example, just yesterday I bought one of these milk coffees you find in supermarkets and foolishly didn't read the label. It had some Carrageenan in it and I had digestive upset and bloating for the rest of they day.

        Based in your post history I would propose it might be a good idea to stop all supplements for a while and focus on nutritious food and a good lifestyle. Taking new supplements to compensate for the negative effects of the old supplements could send you into an even more negative spiral. Especially Vitamin C is very easy to get from foods.

        I've never been a big party attender, but I never went to a party where I didn't probably offend most of the people there by talking about what I was interested in. (Ray Peat)

        B LucHL 2 Replies Last reply Reply Quote 0
        • B
          bioenergetical @Luke
          last edited by

          @Luke

          I don’t think this was about impurities. I’ve taken like 500mg long before (when I wasn’t taking E) and I didn’t really notice anything. I think I just messed up the balance.

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          • B
            bioenergetical @LucH
            last edited by bioenergetical

            @LucH

            I don’t know much about vit C & E synergy but there is something there. Basically, I accidentally overdosed on one of them by taking the C

            but maybe it isn’t the selenium

            LucHL 1 Reply Last reply Reply Quote 0
            • LucHL
              LucH @bioenergetical
              last edited by

              @bioenergetical said in ascorbic acid negative response:

              I don’t know much about vit C & E synergy

              If you think about synergy, I won't think so; not quite so.
              Too much quinones left when taking vit E, K Q10 and so on. The liver can't deal with (to get rid of) => overloaded => feel sick.
              Too much vit E is not advised too. No need for 400 UI every day. 2x/wk is OK, when taking a mix toco. Not one kind (alpha).

              B 1 Reply Last reply Reply Quote 0
              • LucHL
                LucH @Luke
                last edited by

                @Luke said in ascorbic acid negative response:

                Based in your post history I would propose it might be a good idea to stop all supplements for a while

                Well seen. I'd stop one week and then get informed about the interaction between e.g. liposoluble vitamins.
                I can give a link if interested.

                B 1 Reply Last reply Reply Quote 0
                • B
                  bioenergetical @LucH
                  last edited by bioenergetical

                  @LucH

                  I haven’t taken vitamin E this week. Last time I took it, it was a high-ish dose (400iu). Felt good, but I knew that any more would’ve been problematic

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                  • B
                    bioenergetical @LucH
                    last edited by bioenergetical

                    @LucH

                    I took vitamin D (5,000iu) and it stabilized me for now…

                    I heard about vitamin D depletion from E

                    If the C increased my E then this is relevant. This could be a vitamin E overdose in disguise

                    I understand the well intentions behind the “don’t supplement more” but if I already threw the balance off tremendously, then it will be necessary sometimes… the B1 incident was the same way. Yes, there are risks but if I’m in a desperate situation then sitting idly isn’t going to cut it

                    But I would appreciate the link

                    LucHL 1 Reply Last reply Reply Quote 0
                    • LucHL
                      LucH @bioenergetical
                      last edited by

                      @bioenergetical said in ascorbic acid negative response:

                      I would appreciate the link

                      English Corner: Liposoluble vitamins A D E & K – How much fat do we need to absorb them well?
                      *) Vitamins A, D, E & K – How much lipids do we need to absorb vitamins A D E?
                      http://suppversity.blogspot.be/2014/05/vitamin-d-e-k-how-much-and-what-type-of.html
                      Vitamin A (retinol) + bêta-caroten : 3 to 5 g fat.
                      Source: A Fat D-Ficiency
                      http://suppversity.blogspot.be/2011/12/fat-d-ficiency-do-you-really-need-more.html
                      Vitamin E: 3 g fat but a PUFA-diet exhausts toco- and trienols (latent inflammation).
                      Vitamin K (K1 and K2): 35 g fat
                      The quantity of phylloquinone (K1) which enters your blood circulation will be reduced by around 70% if you eat your spinach without a supply of fat (Gijsbers, 1996). The absorption of K2 is 3 times larger with 35 g of lipids in the meal than with 20 g. 6 x less with 8.8 g of FA. (Uematsu et al. 1996). However 18-20g and 12-15g of PUFA are consumed daily by the American man and woman (Kris-Eheton, 2000).
                      Vitamin D : It is the type of fat that will determine the degree of assimilation.

                      Oil-rich in PUFA inhibit the absorption of 25OHD vitamin.

                      (Niramitmahapanya et al. 2011). An oil with a ratio MUFA: PUFA > 1, like sunflower or soybeans, is deleterious.
                      Caution: If you have a high supply of PUFA (omega-3 supplementation or oilseed consumption, with the exception of macadamia nuts which are very rich in MUFA), the blood rate of Vit D and E will often be very low because these 2 vitamins also have an anti-inflammatory action and will therefore be hijacked / diverted from their use as hormones. Details on my forum (in French, but with links in in English):
                      http://mirzoune-ciboulette.forumactif.org/t1357-vitamines-liposolubles-et-matiere-grasse-ratio#15157
                      *) Synergy effect with vitamin E
                      “Vitamin C regenerates vitamin E and vitamin E protects β-carotene, helped in this by polyphenols. In the event of β-carotene supplementation, vitamin C regenerates vitamin E and β-carotene, and β-carotene seems to protect vitamin E without really explaining this phenomenon "(1)
                      Savings effect
                      Vitamin E is not just a vitamin. Vitamin C makes it possible to recycle oxidized vitamin E and thus prolong its lifespan. The same goes with glutathione which is thus saved for other more useful functions (detox). Glutathion is our antioxidant master. Vitamin E protects against the deleterious effects of polyunsaturated fatty acids when the latter are in excess. And it is quickly done!

                      1. John Libbey Eurotext - Anti-oxydants d’origine alimentaire : diversité, modes d’action anti-oxydante, interactions. Auteur : Claude Louis Léger.
                      2. Daniel Raederstorff et al. Br J Nutr. 2015. doi: 10.1017/S000711451500272X
                        => 20 mg Vit E for 10 gr PUFA.

                      *) Factors that facilitate or counter the absorption of vitamin D3
                      http://mirzoune-ciboulette.forumactif.org/t1664-absorption-de-la-vitamine-d-insuffisante#20619

                      • A Magnesium intake neither too high nor too low (RDA Mg: 360 and 420 mg depending on the sex f / m) is favorable. An excess of Mg will thwart the absorption of vitamin D3.
                      • Mono-unsaturated fatty acids facilitate the absorption of vitamin D (olive, avocado, macadamia, for example). Saturated fatty acids (SFA) are probably neutral, at this level. But since these SFA’s contribute to the stability of the membranes, we should take care to have a 50/50 ratio between SFA and MUFA. And as few PUFA as what is necessary for metabolism (1 % = 22 gr. It is already calculated widely. 4 % is the level not to be over. 6 % is deleterious). (Perfect health diet. Jaminet).
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                      • B
                        bioenergetical
                        last edited by

                        my eyes have been tingling, unsure why

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