ascorbic acid negative response
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I took 300mg ascorbate (orally). I thought I needed it since I haven’t really been consuming much fruit this past week (and a lot of sugars). Turns out I didn’t. It felt toxic. What could it have affected? It had this flushing effect. It kinda made me lose my coordination and gave me this odd sensation in my chest. Not sure if I will be good, I still feel weird
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doesn’t vit C antagonize selenium?
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@bioenergetical said in ascorbic acid negative response:
doesn’t vit C antagonize selenium?
PMID: 3088312.
Only high level vit C interferes with the sélénite. -
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I don’t follow, it’s just a standard vitamin C supplement
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This post is deleted! -
I am hypometabolic to begin with, but I was feeling better until I messed with the vit C
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I wonder if this has to do with vitamin E. I’ve taken a high-ish dose of it one of these past weeks. Maybe the vitamin C increased my E levels even more…
In other words:
vitamin C —> vitamin E overload? (or vice versa)
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It could also be some impurities. Dr. Peat talked about lead in ascorbic acid supplements for example. Although I'm not sure a single dose of 300mg would have an immediate effect if it was due to impurities. But who knows, even small amounts of something bad can have a noticeable negative effect. For example, just yesterday I bought one of these milk coffees you find in supermarkets and foolishly didn't read the label. It had some Carrageenan in it and I had digestive upset and bloating for the rest of they day.
Based in your post history I would propose it might be a good idea to stop all supplements for a while and focus on nutritious food and a good lifestyle. Taking new supplements to compensate for the negative effects of the old supplements could send you into an even more negative spiral. Especially Vitamin C is very easy to get from foods.
I've never been a big party attender, but I never went to a party where I didn't probably offend most of the people there by talking about what I was interested in. (Ray Peat)
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I don’t think this was about impurities. I’ve taken like 500mg long before (when I wasn’t taking E) and I didn’t really notice anything. I think I just messed up the balance.
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I don’t know much about vit C & E synergy but there is something there. Basically, I accidentally overdosed on one of them by taking the C
but maybe it isn’t the selenium
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@bioenergetical said in ascorbic acid negative response:
I don’t know much about vit C & E synergy
If you think about synergy, I won't think so; not quite so.
Too much quinones left when taking vit E, K Q10 and so on. The liver can't deal with (to get rid of) => overloaded => feel sick.
Too much vit E is not advised too. No need for 400 UI every day. 2x/wk is OK, when taking a mix toco. Not one kind (alpha). -
@Luke said in ascorbic acid negative response:
Based in your post history I would propose it might be a good idea to stop all supplements for a while
Well seen. I'd stop one week and then get informed about the interaction between e.g. liposoluble vitamins.
I can give a link if interested. -
I haven’t taken vitamin E this week. Last time I took it, it was a high-ish dose (400iu). Felt good, but I knew that any more would’ve been problematic
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I took vitamin D (5,000iu) and it stabilized me for now…
I heard about vitamin D depletion from E
If the C increased my E then this is relevant. This could be a vitamin E overdose in disguise
I understand the well intentions behind the “don’t supplement more” but if I already threw the balance off tremendously, then it will be necessary sometimes… the B1 incident was the same way. Yes, there are risks but if I’m in a desperate situation then sitting idly isn’t going to cut it
But I would appreciate the link
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@bioenergetical said in ascorbic acid negative response:
I would appreciate the link
English Corner: Liposoluble vitamins A D E & K – How much fat do we need to absorb them well?
*) Vitamins A, D, E & K – How much lipids do we need to absorb vitamins A D E?
http://suppversity.blogspot.be/2014/05/vitamin-d-e-k-how-much-and-what-type-of.html
Vitamin A (retinol) + bêta-caroten : 3 to 5 g fat.
Source: A Fat D-Ficiency
http://suppversity.blogspot.be/2011/12/fat-d-ficiency-do-you-really-need-more.html
Vitamin E: 3 g fat but a PUFA-diet exhausts toco- and trienols (latent inflammation).
Vitamin K (K1 and K2): 35 g fat
The quantity of phylloquinone (K1) which enters your blood circulation will be reduced by around 70% if you eat your spinach without a supply of fat (Gijsbers, 1996). The absorption of K2 is 3 times larger with 35 g of lipids in the meal than with 20 g. 6 x less with 8.8 g of FA. (Uematsu et al. 1996). However 18-20g and 12-15g of PUFA are consumed daily by the American man and woman (Kris-Eheton, 2000).
Vitamin D : It is the type of fat that will determine the degree of assimilation.Oil-rich in PUFA inhibit the absorption of 25OHD vitamin.
(Niramitmahapanya et al. 2011). An oil with a ratio MUFA: PUFA > 1, like sunflower or soybeans, is deleterious.
Caution: If you have a high supply of PUFA (omega-3 supplementation or oilseed consumption, with the exception of macadamia nuts which are very rich in MUFA), the blood rate of Vit D and E will often be very low because these 2 vitamins also have an anti-inflammatory action and will therefore be hijacked / diverted from their use as hormones. Details on my forum (in French, but with links in in English):
http://mirzoune-ciboulette.forumactif.org/t1357-vitamines-liposolubles-et-matiere-grasse-ratio#15157
*) Synergy effect with vitamin E
“Vitamin C regenerates vitamin E and vitamin E protects β-carotene, helped in this by polyphenols. In the event of β-carotene supplementation, vitamin C regenerates vitamin E and β-carotene, and β-carotene seems to protect vitamin E without really explaining this phenomenon "(1)
Savings effect
Vitamin E is not just a vitamin. Vitamin C makes it possible to recycle oxidized vitamin E and thus prolong its lifespan. The same goes with glutathione which is thus saved for other more useful functions (detox). Glutathion is our antioxidant master. Vitamin E protects against the deleterious effects of polyunsaturated fatty acids when the latter are in excess. And it is quickly done!- John Libbey Eurotext - Anti-oxydants d’origine alimentaire : diversité, modes d’action anti-oxydante, interactions. Auteur : Claude Louis Léger.
- Daniel Raederstorff et al. Br J Nutr. 2015. doi: 10.1017/S000711451500272X
=> 20 mg Vit E for 10 gr PUFA.
*) Factors that facilitate or counter the absorption of vitamin D3
http://mirzoune-ciboulette.forumactif.org/t1664-absorption-de-la-vitamine-d-insuffisante#20619- A Magnesium intake neither too high nor too low (RDA Mg: 360 and 420 mg depending on the sex f / m) is favorable. An excess of Mg will thwart the absorption of vitamin D3.
- Mono-unsaturated fatty acids facilitate the absorption of vitamin D (olive, avocado, macadamia, for example). Saturated fatty acids (SFA) are probably neutral, at this level. But since these SFA’s contribute to the stability of the membranes, we should take care to have a 50/50 ratio between SFA and MUFA. And as few PUFA as what is necessary for metabolism (1 % = 22 gr. It is already calculated widely. 4 % is the level not to be over. 6 % is deleterious). (Perfect health diet. Jaminet).
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my eyes have been tingling, unsure why
