Grounding improves mitochondrial bioenergetics
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There has been a great deal of hype around grounding or earthing. A list of beneficial effects can be found here. I have not read much information on the underlying mechanisms of its effects.
Earthing effects on mitochondrial function: ATP production and ROS generation (2025)
Abstract
Mitochondria are central to cellular energy production and the regulation of oxidative stress. Traditional methods for assessing mitochondrial ATP and reactive oxygen species (ROS) rely on metal probes, which unintentionally ground the system, confounding results. To investigate the impact of grounding on mitochondrial function, we utilized fluorescence-based experiments to assess these mitochondrial outcomes under three conditions: wired (grounded), sham, and naïve. Mitochondria under grounded conditions produced significantly more ATP (by 5–11%), reduced ROS production (by 22–33%), and decreased mitochondrial membrane potential (by 5–6%) than sham and naïve. These findings indicate that grounding improves mitochondrial bioenergetics by reducing oxidative stress. Future research should explore the broader implications of grounding over time on mitochondrial health and its potential therapeutic applications.
The grounded mitochondria also churned out about 5-11% more energy in the form of ATP. This is a large metabolic boost. Figure 3(C)
Under active energy production conditions, grounding also lowered oxidative stress (hydrogen peroxide production). One would expect that increasing energy production would also increase reactive oxygen species (ROS). But, grounding improves both. Figure 3(D)
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As a grounding mat owner, I want to believe, but it looks like there are only 3 mice/rats by group.
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I LOVE GROUNDING