Grapes are high in boron and so is wine.
Apples too.
Latest posts made by NNight
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RE: Bloodwork shows elevated TPOAb (Hashimoto's disease)
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RE: Bloodwork shows elevated TPOAb (Hashimoto's disease)
Both are involved in the antioxidant system.
It's especially known regarding selenium but I think it's also true for boron.
Boron seems to have a particular affinity with the thyroid which is intriguing.
IMO, boron can be seen as an element that could balance the action of iodine in the thyroid.
I don't think there are papers showing an improvement of Hashimotos with boron though, as I'm not sure it has even been studied.
Keep in mind that too much could be detrimental too. -
RE: Bloodwork shows elevated TPOAb (Hashimoto's disease)
I would say, try to increase your selenium and boron consumption.
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RE: Beyond thyroid: Iodine and PUFA interaction, greater protection than vitamin E?
I believe boron might be important if you consume lots of iodine/iodide, to decrease oxidative stress.
I wonder if kelp contains some boron as well.
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RE: Carbon Monoxide Poisoning from Heme Oxygenase Breaking Down Hemoglobin
I don't know if it will be useful to you (you've already been there and done that), but TonEBP/NFAT5 activation could help deactivating HO-1:
We found that TonEBP is a potent suppressor of HO-1 in human and mouse macrophages.
https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2019.00850/full
The FXR might help too to rebuild heme:
FXR orchestrates the expression of multiple heme biosynthetic enzymes. Finally, human HepG2 cells and primary human hepatocytes treated with obeticholic acid, showed increased expression of several heme biosynthetic genes.
(In the liver...)
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RE: Low salt diet and water restriction
@Razvan
Manganese is interesting as it's part of the SOD2 enzyme which is particularly needed in case of "dehydration".Empirically, I've also found it to gave me what (the energy) you described. But I don't believe it stayed that way very long, I don't remember well.
Also, manganese is interesting as it seems to do positive things regarding the AQP4 aquaporin, which is involved in the glymphatic system (cleansing system of the brain).
In brain, astrocytes predominantly take up and accumulate manganese and are thus vulnerable to its toxicity. Manganese was shown to induce cell swelling in cultured astrocytes, and oxidative/nitrosative stress (ONS) mediates such swelling. As aquaporin-4 (AQP4) is important in the mechanism of astrocyte swelling, we examined the effect of manganese on AQP4 protein levels in cultured astrocytes. Treatment of cultures with manganese increased AQP4 protein in the plasma membrane (PM), whereas total cellular AQP4 protein and mRNA levels were unchanged, suggesting that increased AQP4 levels is due to its increased stability and/or increased trafficking to the PM and not to its neosynthesis.
Aquaporin-4 in manganese-treated cultured astrocytes
They talk about AQP4 in negative terms here but it really seems to be fundamental for the glymphatic system, for example:
CSF transport is facilitated by the expression of aquaporin-4 (AQP4) water channels on the perivascular endfeet of astrocytes. Mice with genetic deletion of AQP4 (AQP4 KO) exhibit abnormalities in the brain structure and molecular water transport.
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RE: My mother and sister think I have an eating disorder...
@thibaud
Ok, maybe all starches are not equivalent in your situation (rice is often said to be more easily digestible for example).
Personally I find some lettuce to be well digested too, but it's something personal and you know better than us what works for youAnyways, welcome to the forum!
Ps: I should have seen that your english was too perfect to be a product of the french education system lol.
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RE: My mother and sister think I have an eating disorder...
The standard answer would be that your diet might be healthier than what you used to eat but is not necessarily optimal as is.
Absolutely no starches nor greens? This seems like a typical "Ray Peat diet".
Don't fall in the "the more atypical my diet is, the more it will be healthy" mentality (I can be a victim of it, I was at least).
You didn't ask that I judge your diet sorry, but adapting your diet and making it more "normal" seems like the only solution. And I am not talking about eating fried PUFA
Are you french?
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RE: Low salt diet and water restriction
@Ecstatic_Hamster said in Low salt diet and water restriction:
Travis told me several times that the process of making oxytocin creates one molecule of vasopressin in addition to the oxytocin, so you have both.
I didn't know their production was necessarily simultaneous, interesting! I believe their degradation might not be though.
I've made a rapid comparison of oxytocin and copper quantities (with help of ChatGPT @sharko ) and they don't match. Copper seems to outnumber oxytocin by a 10^6 factor so this hypothesis seems completely wrong at first sight (except if you consider that it's possible that oxytocin and copper concentrations could be vastly different a the cell's compartment where copper disturbs nuclear receptors activation).