Mysterious gallbladder disease - can't digest fat for no apparent reason
-
Seems like nobody mentioned it so far: When I was unable to digest fat all I needed was to take 4000mg of Taurin and that resolved the issue. Probably not it since you said you could also not digest sugar, but maybe still worth a try.
-
@CrumblingCookie Thank you very much.
I was taking 600-1000mg of alpha-gpc, 250-500mg of B5, 100-200mg of B1 and some TMG-betaine every day since early June until mid-August. I was not taking b12 because it was causing bad toothache, and I was not taking lipoic acid because it caused nausea.
My digestion deteriorated very much during that time, I'm unable to eat even 1800 kcal daily now. I don't think the deterioration is caused by the supplements, but they probably did not helped much either. Nowadays I'm too nauseous to take any supplements at all. It is strange because logically your explanation makes perfect sense. And I'm sure I'm deficient in choline. I don't know why it doesn't work.
I did not touched cyproheptadine or ketotifen (or any similar substance) as an adult. I started receiving asthma medication when I was 5 years old, I didn't know what I'm receiving back then and neither did my parents. I changed doctors very often and they always changed my medication so I might have received cyproheptadine or ketotifen at some point.
-
GABA, while being great for sleep, made my digestion much worse btw. It went away shortly after stopping the supplementation
-
A huge chunk of my molar just crumbled and fell apart after just 5 days of boron supplementation. I've had similar reaction to other forms of boron supplements (glycinate) in the past. Will have to get the prescription for Nystatin, or obtain the medicine by other means
-
@BearWithMe said:
A huge chunk of my molar just crumbled and fell apart
That's not normal. Maybe it's time to up your scope before any more dabbling and to get an abdominal MRI to look for structural constrictions or masses and also your plasma levels of Ca, PTH, CT and a GI hormones panel at a specialized clinic.
-
@CrumblingCookie My plasma level of Ca was elevated every time I had the test done as far back as 2014, except for the last test I did in 2024. My intact PTH was 2,87 pmol/l (or 27 pg/mL) in 2023. Not sure what CT means in this context, is this possibly a typo?
Can very bad case of pectus excavatum create a structural constriction in GI tract? Also I suspect I have hiatal hernia, but my digestive issues most likely predate the hernia
-
@BearWithMe Sorry that the rice and corn didn't work out for you. Did you also try rice noodles? In the past I've noticed huge difference in digestibility between rice - which wouldn't digest well at all - and rice noodles which were very easy to digest. It's a denser carb source and doesn't have as much water.
You've had high blood calcium levels since 2014? That would explain the teeth crumbling situation.... probably not primary hyperparathyroidism though if your PTH is on the low end. What have your vitamin D levels been during this period? And you might've mentioned it already, but have you gotten screened for celiac? In celiac disease you malabsorb vitamin D which then causes secondary hyperparathyroidism and consequent bone loss (https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/486428?). It's part of the reason why I think oats are such a sketchy food since they contain gluten proteins.
-
@Korven
Vitamin D (25-OH)
June 2017: 39,2 nmol/l
June 2024: 133,4 nmol/lI was supplementing D sublingually in 2024 and also getting plenty of sunlight so the results are not a proof of good vitamin D absorbtion. But they do suggest that lack of vitamin D is likely not the cause of teeth crumbling. I was not screened for celiac disease.
I did not try rice noodles yet but I absolutely should do it as soon as possible.
-
@BearWithMe Hmm okay.
Your blood calcium was normal in 2024 after you supplemented vitamin D, right? That points to it being a case of secondary hyperparathyroidism, i.e. deficiency of vitamin D3 and/or calcium.
I am a bit surprised that your doctor never tested you for gluten intolerance. I am probably a bit biased since gluten is very bad for me, but celiac disease could explain many if not all your symptoms. The problem is that you have to eat gluten on a daily basis before getting the tests done, otherwise you won't necessarily see the intestinal damage and you get a false negative.
Edit: I would also like to add that if you had high blood calcium, low'ish vitamin D and potentially high PTH (it can fluctuate and sometimes you get a low-mid PTH reading while it's actually elevated) during the years 2014-2023, that might certainly have contributed to your poor dental health. There is a lot of calcium stored in bones and it can take years before the effects of a calcium/vitamin D deficiency show themselves.
-
@BearWithMe, no need to respond, but just something to consider if you haven’t explored it yet—thyroid function. You may already know all of this, but just in case you don’t, since the thyroid/parathyroid glands are the main glands involved in calcium metabolism and connective tissue integrity, dry skin, herniations, broken teeth/bone loss, structural deformities, depression, exhaustion, heat and/or cold intolerance, and even poor peristalsis (resulting in dysbiosis/overgrowths, reflux etc.) and dehydration (the thyroid and adrenals, being the main power sources of the body, work in concert with each other to control peristalsis and electrolyte balance) are some of the many symptoms of poor thyroid function. I find the most accurate diagnostics to be:
• Temps—taken first thing in the morning, midday and 20–30 minute after eating, including temps of extremities (feet, hands, nose and ears)
• Pulse rate
• Achilles tendon reflex test—there are videos on YouTube showing how to perform it if your doctor won’t
• Evaporation rate/metabolic rate—total fluids consumed and eliminated via sweat vs urine in a 24 hour periodIf thyroid supplementation is needed, it can temporarily make one sensitive to the adrenaline that was compensating for the lack of thyroid hormone so heart palpitations, shortness of breath, overheating and anxiety, basically, what is often mistaken for hyperthyroid symptoms, are common, in which case taking magnesium at the same time can be helpful to reduce symptoms as the thyroid and adrenals adjust. When finding a proper dose, I increase or decrease it by 1/4 grain (or the equivalent dose of synthetic) every two weeks, checking my temps and pulse rate. If taking a natural thyroid glandular/NDT it should be standardized to be most effective.
-
@BearWithMe said:
what CT means in this context
Calcitonin, in the context of (GI) hormones.
Running celiac diagnostics makes sense.
