Statins vs Glucosamine Sulfate
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It is difficult to make a direct comparison but it worth thinking about.
First, the number needed to treat (NNT) is available for many pharmaceuticals. Statins powerfully change cholestrol numbers. They are a multibillion group of drugs. However, the NNT for statins not very impressive.
https://thennt.com/?s=statins&x=0&y=0
Here is a mouse study.
Treatment with chondroitin sulfate to modulate inflammation and atherogenesis in obesity (2015)

The goal is to prevent heart attacks and death in humans.
RESPONSE OF ISCHEMIC HEART DISEASE TO CHONDROITIN SULFATE-A* (1969)Also from Dr. Lester Morrison, an internal medicine specialist at Loma Linda University Medical Center reported in the journal ANGIOLOGY that four groups of sixty (60) high-risk angina (chest pain) patients with coronary artery disease were successfully treated with a dietary supplement (chondroitin sulfate) over a six-year period. Here were the results of that study:

Volume 25, page 269, 1973
Coronary Heart Disease: Reduction of Death Rate By Chondroitin Sulfate a -