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Is High Dose Benadryl Peaty?

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  • R
    Rapist Banned
    last edited by Jan 30, 2024, 12:39 AM

    Are high doses of diphenhydramine overall beneficial to hormonal profile and health? If it has deleterious effects, how can you mitigate them? I’m an avid Benadryl enjoyer but I want to make sure I’m taking care of my well being at the same time.

    H F S J N 5 Replies Last reply Jan 30, 2024, 12:40 AM Reply Quote 0
    • H
      honest_skeptic @Rapist
      last edited by Jan 30, 2024, 12:40 AM

      @Rapist Yeah... I don't this is a good idea whether your a Ray Peat follower or not... You know people often die from overdosing on DPH, right? Ever hear of Eiriel?

      F 1 Reply Last reply Jan 30, 2024, 12:44 AM Reply Quote 0
      • F
        Fructose @Rapist
        last edited by Jan 30, 2024, 12:42 AM

        @Rapist said in Is High Dose Benadryl Peaty?:

        Are high doses of diphenhydramine overall beneficial to hormonal profile and health? If it has deleterious effects, how can you mitigate them? I’m an avid Benadryl enjoyer but I want to make sure I’m taking care of my well being at the same time.

        There are many studies that have shown that the use of diphenhydramine increases cholinesterase activity in the CNS. Possibly increases cerebral cortex and decreases acetylcholine.

        1 Reply Last reply Reply Quote 0
        • F
          Fructose @honest_skeptic
          last edited by Jan 30, 2024, 12:44 AM

          I do not recommend overdosing. Maintaining safe doses will be effective. As the previous speaker mentioned, an overdose often ends in death.

          1 Reply Last reply Reply Quote 0
          • C
            chrome
            last edited by Jan 30, 2024, 12:50 AM

            I think Peat said it was okay in normal doses but you shouldn't overrely on it. Overdosing or tripping on it wouldn't be good. It also has harmful excipients. It does lower histamine and serotonin which is good.

            H 1 Reply Last reply Jan 30, 2024, 12:51 AM Reply Quote 0
            • H
              honest_skeptic @chrome
              last edited by Jan 30, 2024, 12:51 AM

              @chrome Tripping on it is a death sentance. It's one of the few deliriants, which is in the same category as Datura, so you know its some hardcore shit

              1 Reply Last reply Reply Quote 0
              • S
                solgirl @Rapist
                last edited by Jan 30, 2024, 12:55 AM

                @Rapist Why is @brad allowing these usernames??

                Peace & Love

                F 1 Reply Last reply Jan 30, 2024, 12:56 AM Reply Quote 0
                • F
                  faggot Banned @solgirl
                  last edited by Jan 30, 2024, 12:56 AM

                  @solgirl mind your business

                  R 1 Reply Last reply Jan 30, 2024, 2:30 AM Reply Quote 0
                  • R
                    Rapist Banned @faggot
                    last edited by Jan 30, 2024, 2:30 AM

                    @faggot thanks faggot ❤️

                    1 Reply Last reply Reply Quote 0
                    • J
                      JoseYamamoto @Rapist
                      last edited by Jan 30, 2024, 3:09 AM

                      @Rapist What's your goal with high dose Benadryl? And have you found a clean source without excipients?

                      Dare to bare your heart

                      1 Reply Last reply Reply Quote 0
                      • N
                        NangaParbat @Rapist
                        last edited by Jan 30, 2024, 3:20 AM

                        @Rapist Watch 1st gen antihistamines are good in moderation, but in high dose, and especially if you are on some bulgarian cocktail, present a very real risk of serotonin syndrome.

                        A 1 Reply Last reply Jan 30, 2024, 3:57 AM Reply Quote 0
                        • A
                          ah
                          last edited by Jan 30, 2024, 3:54 AM

                          I avoid benadryl after seeing the recent studies showing significantly increased risk of alzheimers even in moderate users
                          I realise these are epidemiological studies but still, if you need an antihistamine take cypro or maybe pizotifen instead

                          1 Reply Last reply Reply Quote 0
                          • A
                            ah @NangaParbat
                            last edited by Jan 30, 2024, 3:57 AM

                            @NangaParbat 1st gen antihistamines (particularly cypro) are used as an antidote for serotonin syndrome, I dont see how it could cause it

                            N 1 Reply Last reply Jan 30, 2024, 4:24 AM Reply Quote 0
                            • N
                              NangaParbat @ah
                              last edited by Jan 30, 2024, 4:24 AM

                              @ah Dosage makes the poison.

                              1 Reply Last reply Reply Quote 0
                              • B
                                Big_El
                                last edited by Jan 30, 2024, 10:57 AM

                                It’s a demonic drug controlled by an evil entity called hatman, avoid under all circumstances.

                                1 Reply Last reply Reply Quote 0
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