Nobiletin for fatty liver:
Helps with fatty liver and fibrosis via increasing adiponectin and SOD while lowering MDA
https://pubmed.ncbi.nlm.nih.gov/38073108/
Helps via modulating Nrf2
https://pubmed.ncbi.nlm.nih.gov/38073108/
Helps via altering the gut microbiome
https://pubmed.ncbi.nlm.nih.gov/37139957/
Helps via lowering oxidative stress and lipid peroxidation and increasing ATP.
https://pubmed.ncbi.nlm.nih.gov/34695558/
Helps via increasing cholesterol to bile acids conversion ( increasing CYP7A1, and CYP27A1), increasing SCD1 and LXRa and lowering FAS.
So should be good for people with high cholesterol ,low bile production/flow.