Random, interesting studies
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Pregnenolone reduces cocaine consumption in addicts.
Dosage: 300 or 500mg per day.Also interesting that 300mg increased plasma pregnenolone levels more than 500mg after a few weeks.
https://www.medrxiv.org/content/10.1101/2025.01.07.25320141v1.full
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Aspirin for autism?
In this animal model aspirin worked as a treatment for autism.
It completely restored their sociability and improved cognition and oxidative stress.
The human equivalent dosage was around 600mg.
https://pubmed.ncbi.nlm.nih.gov/40918592/ -
They accidentally gave 2 million IUs of vitamin D to a 90 and a 95 year old.
Interestingly, except for a transient spike of Vitamin D levels above the reference range, they were fine. -
DHEA seems to have some interesting antiviral effects.
At least partly because of its ability to protect the thymus gland from Glucocorticoids.
Sources:pubmed.ncbi.nlm.nih.gov/20407244/
pubmed.ncbi.nlm.nih.gov/1835439/
pubmed.ncbi.nlm.nih.gov/18682333/
pubmed.ncbi.nlm.nih.gov/2141095/
pubmed.ncbi.nlm.nih.gov/18462821/
pubmed.ncbi.nlm.nih.gov/2974468/
pubmed.ncbi.nlm.nih.gov/20202657/ -
Just wanted to add my thanks to @Mauritio for continuing to add to this fascinating collection of studies.
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@rpc thanks!
I posted them on twitter during the last weeks. But it seems to me that there is less overlap between the audience on here and twitter, than I thought. So I'll try to post them on both platforms in the future.Dare to think.
My X:
x.com/Metabolicmonstr -
@rpc said in Random, interesting studies:
Just wanted to add my thanks to @Mauritio for continuing to add to this fascinating collection of studies.
Ya, me too. Good job.
Even when there is no comment. At least you can see the random reading, I suppose. Has to be confirmed: => eye logo 29.8k -
@rpc he is great
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@Mauritio i dont go on twitters unless u post a nitter link as im too lazy to go on nitter for ur account myself
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@Mauritio in my opinion it will be smarter to create a new post for each study so that they dont get drowned in a sea of others
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@lobotomize most of them are just random studies without much context. Usually when I create a thread I give more context. This serves more as a notepad. And if people look for a specific substance they will find it though the search function.
Dare to think.
My X:
x.com/Metabolicmonstr -
@Mauritio just dropping a title about... doing... can make it have a much longer lifespan and can even help some random person years later (as many well named threads in the Rayp forum still do). Extra context can be retrieved by the average curious georgi with minimal tech literacy
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@lobotomize yeah you have a point. Maybe I'll make some of larger posts (like the coca one)into a thread.
When I start I never know what a posts turns out to be, because it depends how much fun it is to research it, so that's why i just drop all the studies here. -
Theobromine drastically Upregulated UCP1 AND PGC1a. Only in vitro, set still interesting.
Been wanting to try it for a while .
Dare to think.
My X:
x.com/Metabolicmonstr -
@Mauritio - Have you considered food sources?
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@Mauritio - Have you considered food sources?
Foods Ranked 1 - 20 With Theobromine
My expectations for such a list were low but nevertheless beaten by such impressive stubborness:
It's only variations of cocoa and chocolate!
Now we know of your imaginations of a well-varied, balanced diet. Made me chuckle.
