My (Male) Experience of High Dose Progesterone
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As an early-twenties male I started taking oral progesterone powder to help severe depression. Overall it has been positive. My mood and cognition has permanently improved. Long-term memories have come back sharper than they were before. My face is more healthy-looking and attractive.
I did get knocked out a few times at higher doses.
The dose was ramped up until I felt an effect. At seven grams dosing there was still no effect felt and I decided not to go higher. This first week it felt like my brain was healing. Then as my body got more sensitive to it, I had an episode of severe sedation and could have fallen and gotten injured but luckily I survived.
So I continued lowering the dose over the months, occasionally taking DHEA for androgen balance, had another episode of extreme sedation (these come out of the blue), etc.
No feminizing effects for me, no change in facial hair growth. It noticably made my face appear healthier and more attractive. I am no longer sensitive to bright lights.
There was a thinning and lightening of p*bic hair and armpit hair. One time I abruptly stopped for a week and my d**k shrank until resuming.
I realized it was starting to make me chronically disinhibited and more confident and more outgoing but it was as if I was drunk all the time. At this point I switched to low dose topical CortiNon and Progestene usage. This has been great and my p*bic hair is back to normal.
The oral progesterone was taken alongside milk which I believe has a protective effect on the gut against potential impurities like residual solvents.
It did not resolve apathy and anhedonia.