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    Black Ginger (K. parviflora)

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    • lobotomizeL
      lobotomize
      last edited by lobotomize

      A human study: single oral intake of 50 mg K. parviflora extract increased whole-body oxygen consumption and decreased respiratory quotient (RQ) during moderate exercise.
      ResearchGate

      A rodent study: feeding 1.0% KPE increased whole-body energy expenditure in mice fed a high fat diet.
      PMC

      https://www.researchgate.net/publication/286468896_Effect_of_Kaempferia_parviflora_extract_on_oxygen_consumption_and_respiratory_quotient_by_the_single_oral_intake_-_A_randomized_double-blind_placebo-controlled_cross-over_study

      AMPK activation. Flavones such as 5,7-dimethoxyflavone (DMF) and 5,7,4′-trimethoxyflavone increase AMP/ATP ratio → activate AMPK → raise fatty-acid oxidation and mitochondrial biogenesis.

      β-adrenergic signalling. Some studies show increased norepinephrine or cAMP levels in adipose tissue → induces UCP1 and UCP3 expression in brown and beige fat.

      UCP1-mediated thermogenesis. Upregulation of uncoupling protein 1 allows controlled proton leak via physiological channels instead of chemical proton shuttling.

      Endothelial NO and circulation effects. Black ginger improves nitric-oxide-dependent vasodilation, indirectly enhancing oxygen delivery and metabolic rate.

      Possible mild direct mitochondrial modulation. Some flavones alter mitochondrial membrane potential in vitro, but magnitudes are small and reversible; they do not show classical protonophore activity like DNP.

      https://pmc.ncbi.nlm.nih.gov/articles/PMC4256566/?

      @Mauritio @cs3000

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      • MauritioM
        Mauritio
        last edited by Mauritio

        Interesting. I've never heard of that type of ginger.

        It seems to be adrenergically medicated.
        Not necessarily something id like long term ,but short term for weight loss might be fine.
        Seems to work better in people with high BAT
        https://pubmed.ncbi.nlm.nih.gov/25994142/

        No effect on testosterone here
        https://www.cabidigitallibrary.org/doi/full/10.5555/20133199963

        Dare to think.

        My X:
        x.com/Metabolicmonstr

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