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    The anti-cortisol mechanism of trenbolone

    Scheduled Pinned Locked Moved Literature Review
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    • alfredoolivasA Offline
      alfredoolivas
      last edited by alfredoolivas

      4c8871c5-287b-48c8-9a06-aa54ad7e0a1f-image.png

      It decreases faty acid synthase, ACC in liver, adipose and muscle and LIPOLYSIS IN ADIPOSE TISSUE. It increases lipolysis in the liver and muscle, but allows adipose tissue to not release FFA into the blood!
      10.1055/s-2007-1018919

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      • alfredoolivasA Offline
        alfredoolivas
        last edited by

        Seems to make turkeys with weak legs more excitable, indicating it increases intracellular calcium
        cfec36a0-9054-4353-aac0-d92faa12e3bc-image.png

        10.1080/00071688108447879

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        • alfredoolivasA Offline
          alfredoolivas @alfredoolivas
          last edited by

          " the anabolic action of TP and TBA, especially in female rats, may be mediated through an antagonistic effect to the catabolic effects of oestrogens and glucocorticoids."
          https://www.semanticscholar.org/paper/Effect-of-sex%2C-testosterone-propionate-and-acetate-Santidriรกn-Thompson/64ece3bf3a3cd424d83611cfad2d54f94912c41c

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          • alfredoolivasA Offline
            alfredoolivas
            last edited by alfredoolivas

            decreases FFA " Plasma triglyceride concentrations in all
            implanted groups fell markedly by week 5 and remained well
            below control values until slaughter. The concentration of
            plasma non-esterified fatty acids decreased by approximately
            50% in all four treatment groups
            "

            b6eb3ab6-0ebb-40ad-b7a7-ed03abace780-image.png

            f4366e4a-b08a-4a61-95b5-1ff3cedf07b4-image.png

            Low doses of tren & E2 had lower cholesterol.

            https://pubmed.ncbi.nlm.nih.gov/7152469/

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            • alfredoolivasA Offline
              alfredoolivas
              last edited by

              "TB A also had no effect on either the digestibility or metabolizability of the energy in the diet, or on the total energy retained by the two experimental groups...there were significant differences in the way this energy was partitioned for growth between treated and control animals. "

              It doesn't cause fat loss via increasing metabolism?

              https://www.researchgate.net/publication/231925431_The_effect_of_trenbolone_acetate_on_growth_rate_and_carcass_composition_of_young_female_rabbits

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              • alfredoolivasA Offline
                alfredoolivas
                last edited by

                " Trenbolone, however, did not demonstrate any genotoxic effect in the assays performed."
                https://pubmed.ncbi.nlm.nih.gov/3090982/

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                • alfredoolivasA Offline
                  alfredoolivas
                  last edited by alfredoolivas

                  a2097a76-0e88-4866-88ac-9d05c7ba9277-image.png
                  Decreases fat cell size

                  adef3e8f-aea9-457c-9d38-217b5e58d4a8-image.png
                  Decreases FAS and increases G6PD and other genes involved with NADPH formation

                  https://pubmed.ncbi.nlm.nih.gov/3583947/

                  200mg TBA implant given once every 56 days with a 60 day withdrawal period.

                  I am not going to even estimate the amount of tren built up and released lol

                  But that is 3.57mg TBA (2.85mg elemental weight) every day given to Heifers, with a 60 day withdrawal period.
                  9dd8310f-fc83-4fff-94fd-8a5140cc2e82-image.png

                  French were giving 5mg a day to 65kg humans XDXD.
                  Bro if 2.85mg of trenbolone can do this to a HEIFER after 60 days of no tren then imagine what 5mg does to a human @engineer

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                  • alfredoolivasA Offline
                    alfredoolivas @alfredoolivas
                    last edited by

                    I think tren only cycles may be good, because OVX with tren was often more effective than tren by itself.

                    Lowering endogenous sex steroids like progesterone, estradiol and test WITH tren can be even more anti-lipolitc.

                    bee75c2e-c1dc-4265-a5b3-6727cd26da85-image.png

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                    • alfredoolivasA Offline
                      alfredoolivas @alfredoolivas
                      last edited by

                      @sunsunsun my inuition may be correct๐Ÿ˜‰ ๐Ÿ˜‰

                      @sunsunsun said in moggy chicken log:

                      @alfredoolivas but why u think androstane avoidance is le good

                      @alfredoolivas said in moggy chicken log:

                      @sunsunsun intuition๐Ÿ˜‰

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                      • sunsunsunS Offline
                        sunsunsun @alfredoolivas
                        last edited by

                        @alfredoolivas y tho

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