Some of your symptoms sound like mine (not all), I've also had the poisoned feeling many times.. I have mild crohns disease, according to a colonoscopy back in 2017.
One thing that has helped me when I get real fatigued and body pains is taking bupropion, and the inflammation went down quite a bit, no more poisoned feeling and an increase in energy (probably because it increases norepinephrine). But I don't like being on pharmaceuticals and it wasn't curing the issue, just mitigating some of it.
I usually go on it for 30-60 days and then go back off until things get bad again.