@DarthGomas said in Coffee weird effects:
If I start using it regularly, it drastically reduces my energy, makes me very irritable, and gives me a sensation as if my body is burning (in a bad way).
Coffee blocks thiamine.
"As thiamine is an essential micronutrient for humans its needs are supplied from diet rich in thiamine, such as yeast, pork, legume and cereal grains. Enzyme called thiaminase I (EC2.5.1.2), present in raw fish, shellfish, tea and coffee, decreases thiamine absorption."
also this one:
https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2019.00207/full
"Heavy consumption of tannin-containing or food rich in caffeine, theobromine, and theophylline (such as those present in coffee, chocolate, and tea, respectively) can inactivate thiamine, thereby compromising the thiamine status (7, 14, 15)."
and this one:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753639/
"Plant-derived anti-thiamine factors, heat-stable compounds known as polyhydroxyphenols, which include caffeic acid, phenols, flavonoids, and tannins, are present in certain plants and destroy thiamine by an oxidative process that transforms it to non-absorbable thiamine disulfide [17,63,66,87,88,89,90]. Plants containing polyhydroxyphenols include coffee, tea, and some fruits and vegetables, such as blueberries and red cabbage [17]. "
The experts can't seem to agree on exactly what in the coffee messes with thiamine (thiaminase I? caffeine? polyhydroxyphenols??) but they know it's something. I had a terrible reaction to a few sips of coffee when I was thiamine deficient and it nearly made me collapse onto the floor. I don't try to drink it anymore.