@Lejeboca - thank you for taking the time to respond. I got things twisted around in my mind and it is embarrassing.

I think of the relationship between the eNOS and iNOS isoforms of nitric oxide synthase as being analogous to Dr. Jekyll and Mr. Hyde. The "i" in iNOS is related to inflammation, ischemia and intoxication all of which are generally bad. Whereas the "e" is related to the endothelium and is very healthy to have on board. Caldwell Esselstyn had his cardiac patients eat greens all day to maintain high levels of eNOS as part of his successful plan to reverse heart disease.

In 1998, the Noble Prize in Medicine was awarded to 3 people for their work on NO (see press release). This encouraged people to supplement with L-arginine to lower their blood pressure. The excessive iNOS from the supplementation had long term consequences that were not good.

Incidentally, aspirin releases eNOS.
Aspirin induces nitric oxide release from vascular endothelium: a novel mechanism of action (2009)