Edema with water logged lungs / heart atrial fibrillation / pleural fluid around the lungs - approach to fix

[cs3000]

I might edit in some studies later but quick post ,

if someone is hospitalized with edema in the feet and fluid around the lungs (pleural effusion) with afib, (i.e water logged cells)

goal = to establish carbon dioxide production in the cell , bind cellular calcium & get water out.
ray talked about a case where a cancer patient who couldnt speak due to throat swelling was in a chamber where they pumped in too much co2 by mistake. the guys bed was soaked with water and when he woke up he could speak again.
often digoxin is prescribed for the afib, far as medications go maybe better than beta blockers its endogenously produced , related to progesterone. prolonged diuretics might make the situation worse through depleting water soluble vitamins. the core of it is probably low co2 failing to get water out of cells

A simple solution can sometimes be taking vitamin b1 to restore from depletion, which can reverse things quick (this condition is known as beri beri), and vit b1 can be depleted in people who drink alcohol often. (hospitals might not even look at the basics)

muscle / nerve fatigued = swells, retains water, loses ability to relax contract properly. thyroid hormone creates an increase in calcium binding proteins. when co2 is up in the cell it reacts with water forming an acid, and leaves the cell pulling water out, which also pulls out some calcium with it so the cell can relax

Lower:

• aldosterone
• estrogen (inhibits calcium binding protein so cell cant fully relax, works with adrenaline to promote vessel constriction, causes leaky capillaries)
• adrenaline ( makes vessels more permeable)
• lactic acid

Raise:

• co2

• sodium (GRADUALLY - iv saline can worsen things as typical 0.9% is too high, the sodium and chloride is higher than in blood, especially the chloride https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794509/*)

• thyroid

• carbs
  ,

• vit b1 (or b complex but best to start with a low dose, u dont need more than a few milligrams) (vit b1 needed to enable the krebs cycle for co2 production, so this alone being depleted is 1 known cause of this problem)

• coq10 might be worth adding

• hesperidin too (edema study in humans, helps restructure aged heart)

• good salt intake and low water (helps lower aldosterone which increases vessel permeability, sodium can combine with albumin flowing in circulation to act as a pulling force for water inbetween cells, also lowers adrenaline)

• baseline of protein intake to avoid the edema deficiency induces (1 angle is lower albumin if low enough i guess)

• maybe best to avoid aspirin for now

• generally fixing hypothyroid , (ppl at upper end of t3 range have lowest incidence of afib at 3.9% vs 15.6% in lower half of reference range. the confusion here is when people connect t4 to this, which is often not linear with t3 and higher t4 can actually be a sign its not converting enough. t3 is vital for the heart , and the heart especially is reliant on t3 as it doesnt work with t4 well )

Carbon dioxide is powerfully involved in the regulation of both sodium and calcium, as well as in respiration and energy production. . It tends to relax both nerves and muscles. It is apparently one of the essential factors in prevent- ing edema.

C02, when it is in water, especially with the carbonic anhydrase enzymes, combines with water. As it is formed in the mitochondria, this means that it will carry water (as well as calcium and sodium) out into the cytoplasm, and out of the cell
the flow of lactate and other organic ions into the mitochondrion can produce calcium accumulation in the mitochondrion, during conditions in which carbon dioxide synthesis, and consequently urea synthesis, are depressed

Proteins are very large molecules, which don't pass very easily through the walls of blood vessels — and if they do leak out of the blood vessels into the space around cells, there are enzymes there that can dissolve them So the blood stream maintains a high concentration of proteins, normally, which by osmosis tends to make water enter the blood from the space around the tissue cells. These proteins are largely produced by the liver. If the liver isn’t functioning well, or if there is general stress, or if there isn't enough protein in the diet, these proteins tend to disappear, with the result that water accumulates outside the blood vessels. In the morning, this water will be visible as puffiness in the face, especially under the eyes, but by evening gravity will have moved it to the feet and ankles.

Myxedema, which results from insufficient thyroid hormone, involves leakage of proteins out of the blood vessels, and apparently a shortage of the enzymes which should dissolve them. High estrogen blocks various proteolytic enzymes, apparently including those which release thyroxine from the colloid in the thyroid gland since it causes colloid to accumulate (colloid goiter) while reducing hormone release. It also antagonizes the actions of thyroxine on tissues. Besides eating adequate protein, it is necessary to have adequate vitamin A and zinc for efficient protein synthesis. Vitamin C and rutin (grapefruit is a good source) are needed to maintain integrity of blood vessel walls. Other nutrients are needed for normal liver functioning.

Women, like cows, will puff up with water and fat under the influence of estrogen, and wrinkles will naturally be smoothed out. but the skin Itself is actually losing its elasticity faster when estrogen is used.

albumin’s plasmatic abundance, the majority of albumin is not in circulation, as 60% is stored in the interstitial space.23,28 In fact, although the half-life of albumin is about 17 days, albumin only lasts 16–18 h in circulation.23,24 The transcapillary escape of albumin can be reverted, as albumin can eventually return into the plasma component via lymphatic return to maintain steady plasma concentrations. Albumin contributes to 75% of the plasmatic oncotic pressure, which is disproportionally high since albumin only accounts for 50% of plasma proteins.28 That can be explained by albumin’s low molecular weight, which results in high osmotic activity per gram.23 Additionally, the osmotic activity of albumin increases by its negative charge, which holds osmotically active sodium cations

• alodsterone increases vegf / vascular permeability factor, which causes capillaries to become leaky

• While increased salt in the diet tends to lower both aldosterone and VEGF, reducing the leakiness of blood vessels, sodium also has a direct effect that tends to prevent the leakage of water and albumin out of the blood vessels, helping to maintain the blood volume which is needed to perfuse the kidneys, preventing them from producing signals to increase blood pressure and aldosterone

• . There is a large amount of albumin in the blood serum, and sodium ions associate with the negative electrical charges on the albumin molecule. This association causes the complex of albumin and sodium to attract a large amount of water, that is to exert osmotic or oncotic pressure. This oncotic pressure causes any excess extracellular water to be attracted into the blood vessels, preventing edema while maintaining the blood volume. When there is too little sodium, the albumin molecule itself easily leaves the blood stream along with the wate

• The physiological loss of sodium occurs when energy metabolism fails, as indiabetes, hypothyroidism, hyperestrogenism, and starvation. What these conditions have in common is an increased level of free fatty acids in the blood. Increased free fatty acids impair the use of glucose. The consumption of carbohydrate, like an increase of thyroid hormone, insulin, or progesterone, increases the retention of sodium; fructose is the most effective carbohydrate (Rebello, et al., 1983).

The loss of sodium is often accompanied by the retention of water, reducing the osmotic pressure of the body fluids. The leakiness of blood vessels allows the extracellular fluid volume to increase, as understood in the standard definition of edema.

• However, when this fluid is hypo-osmotic, it will enter cells, causing them to swell. Cell swelling excites cells (Ayus, et al., 2008; Baxter, et al., 1991), and can kill them if they are unable to produce enough energy to restore their original volume, by measures including the excretion of amino acids and potassium

• The increase of adrenalin,f caused by a deficiency of sodium, is one of the factors that can increase blood pressure; if the tissues's glycogen stores are depleted, the adrenalin will mobilize free fatty acids from the tissues, which tends to inhibit energy production from glucose, and to increase leakiness.
• After I had read Tom Brewer's work on preventing or curing preeclampsia with added salt, I realized that the premenstrual syndrome involved some of the features of preeclampsia (edema, insomnia, cramps, hypertension, salt craving), so I suggested to a friend that she might try salting her food to taste, instead of trying to restrict salt to "prevent edema." She immediately noticed that it prevented her monthly edema problem. For several years, all the women who tried it had similarly good results, and often mentioned that their sleep improved.

---

Respiring cells are always producing some water, by transferring hydrogen from fuel molecules to oxygen. Respiration also produces carbon dioxide, which in itself is a Lewis acid (meaning that it binds electrons, rather than releasing protons), that associates with cellular proteins, acidifying them in the process. A large amount of carbon dioxide can exist inside cells in the bound form. Acidified cytoplasm (like any other mostly acidic polymer-gel) releases water and sodium

Besides binding with the cytoplasm, the carbon dioxide can be changed into carbonic acid, by chemically combining with water. Carbonic acid is hydrophilic, and so it quickly leaves the cell, taking with it some of the oppositely charged ions, such as calcium and sodium. The formation of carbonic acid, which is constantly streaming out of the respiring cell, causes some water and some positively ionized metals to leave the cell, in an "active" process, that doesn't require any mysterious pumps.

Since respiratory metabolism, governed by the thyroid hormone, is our main source of carbon dioxide, it's obvious that thyroid deficiency should impair our ability to regulate water and solutes, such as salt. An organism that illustrates this function of thyroid is the young salmon, when it leaves a freshwater river to begin its life in the ocean. As it converts its physiology to tolerate the salty environment, its thyroid hormone surges. When it's mature, and returns to the fresh water to spawn, its prolactin rises sharply. In experiments with rodents, it has been found that drinking a large amount of water increases their prolactin, but the same amount of water, with added salt, doesn't.

Hypothyroidism is typically associated with increased prolactin secretion. Hypothyroid people typically retain water, while losing salt, so the hypothyroid state is analogous to the salmon that has returned to the river, and to the mice that drink too much salt-free water.

The typical hypothyroid person loses salt rapidly in the urine (and probably in the sweat, too, though that is usually diagnosed as cystic fibrosis), and retains water, diluting the urine less than normal. The reduced production of carbon dioxide, with increased susceptibility to producing lactate and ammonium, causes the cells to be more alkaline than normal, increasing their affinity for water. The rise of estrogen that usually accompanies hypothyroidism also increases intracellular pH, loss of sodium, and over-hydration of the blood.

s the blood passes through the lungs, carbon dioxide leaves the system, and as carbonic acid is converted to carbon dioxide, water is left behind in the blood

Hypothyroid muscles typically retain excess water, and fatigue easily, taking up more water than normal during exertion. In childhood, mild hypothyroidism often causes the leg muscles to swell and ache in the evenings, with what have been called "growing pains." When the problem is more extreme, all the skeletal muscles can become very large (Hoffman syndrome), because of the anabolic effect of over-hydration.

A lack of salt stimulates the formation of serotonin, [seen this in a study, big increase] which in turn stimulates aldosterone synthesis--that is, a sodium restricted diet activates processes that cause cells to take up sodium inappropriately, in a situation reminiscent of the calcium deficient diet causing inappropriate calcification.

Pregnenolone can sometimes very quickly allow swollen tissues to release their water. This function is probably closely related to its antifibromatogenic function, since swelling and leaking set the stage for fibrosis.

Thyroid hormone, by maintaining oxidative metabolism with the production of carbon dioxide, is highly protective against excessive water retention and loss of sodium and magnesium.

The swollen heart, like any muscle, loses the ability to quickly and completely relax, and so it doesn't fill adequately between contractions. Elastic tissues, such as arteries and lungs, stiffen when they are over-hydrated, losing their normal functions. In small blood vessels, swelling narrows the channel, increasing resistance to the flow of blood.

When people force themselves to drink a certain amount of water every day, even when they don't feel thirsty, they are activating complex adaptive processes unnecessarily. Thirst is the best guide to the amount of fluid needed.

When extra water consumption is combined with a low salt diet--as physicians have so often recommended--a healthy person can adapt easily, but for a hypothyroid person it can have disastrous effects.

In many cases, the vascular leakage of inflammation and shock can be corrected by using osmotically active substances, such as starch solutions, gelatin, or concentrated sodium chloride.

[herayclitus]

This is an excellent and comprehensive post on edema, I think you covered pretty much all the core issues. Progesterone, sodium, caffeine, and ample calorie intake are all good places to start with any fluid retention issues.

[ThinPicking]

This may be the best of the bunch.

Thank you.

[yerrag]

@cs3000

I had heart failure last year. It started with bronchitis from my oral intake of cinnamon bark oil which irritated the cells in my lungs, caused mucus to form, and the mucus wasn't cleared as the ciliary cells were just as irritated and couldn't do their normal job of clearing the mucus for excretion.

This made my lungs unable to do gas exchange properly, and this meant my intake of oxygen became irregular, where my spO2 would drop to 84 for long stretches.

I didn't see a doctor, thinking this condition would resolve itself over time. But it never did. I should, in hindsight, have at least consulted a pulmologist and she would have given me some drugs such as antibiotics to prevent an infection, as well as corticoids to lessen the inflammation to at least improve gas exchange, and some mucolytics and expectorants to clear the lungs of blockages due to phlegm.

Over a 5-month period, my condition worsened as the only thing I did was to supplement oxygen and carbogen. But I was refusing to admit I needed more help while I would have hard time breathing sporadically. This came to a climax as my waistline bulged and my ankles became bloated and the bloat got to my calves. I tried to be calm about it thinking I would be able to resolve this edema. But the signs were there. My ECG looked bad, indicating I have liquid in my lungs from the low height of my QRS curve. These were all signs pointing to heart failure. And sure enough, I collapsed and was taken to the ER. The ER intubated me just before my heart stopped. It took 15 minutes to revive me. Without the intubation, my brain would not have lasted and I would be brain dead.

At the ICU, with the intubation, and with two IV antibiotics, and with diuretics, I regained back my regular breathing and my edema was quickly gone, but not without experiencing painful cramps as a result of the use of diuretics. It took only 2 days to go from the ICU to a regular room for me to continue with my week-long IV antibiotic therapy before finally being discharged.

But recuperating at home, I wasn't totally out of the woods. It took about 8 more months to get to see my ECG to look normal as the lungs were still having some water, a condition called pleural effusion. But key to my recovery this time was in getting my lungs back to a state of good health. As good oxygen intake reestablished was essential to get my metabolism and health back.

I had given a lot of thought figuring out edema. I wish Ray's thoughts on it would pave the way for understanding the mechanism behind edema, but it wasn't enough, despite personally experiencing it in a very advanced form, for me to connect the dots.

I am now back to my regular non-edematous state, but only because I cheated, and stopped taking my bp lowering drugs, which my cardio keeps insisting but wrongly. is the cause for my heart failure.

[Razvan]

Good stuff with the low water. One of the best things i've done recently for my health is not drinking any water and lowering my liquid intake, altought I think low liquid intake is paired best with medium low salt intake and higher potassium intake.

I think plain water is so damaging, the reccomandation of drinking water started in 1960-1961. If I feel too thirsty I just eat some watermelon.
Still need to think about the sodium intake on this one.

[DavidPS]

There is good information in this thread. Thany you (all).

User: how to reduce edema?

Peatbot.com: To reduce edema, consider the following strategies based on the provided context:

1. Increase Protein Intake: Ensure you are consuming enough protein, as proteins help maintain the osmotic pressure that keeps water in the blood vessels. Low protein levels can lead to water accumulation in tissues.

2. Monitor Sodium Intake: While too much sodium can cause water retention, a deficiency can also lead to edema. Balance your sodium intake to ensure it is neither too high nor too low.

3. Support Liver Health: The liver produces proteins that help maintain fluid balance. Eating liver at least twice a week and avoiding allergens that could disturb liver function can be beneficial.

4. Consider Hormonal Balance: High estrogen levels can promote sodium retention and water accumulation. Natural progesterone might help in reducing estrogen's effects and improving fluid balance.

5. Vitamin and Mineral Support: Ensure adequate intake of vitamins and minerals that support protein synthesis and blood vessel integrity, such as:

• Vitamin A and Zinc: For efficient protein synthesis.

• Vitamin C and Rutin: To maintain the integrity of blood vessel walls.

• Vitamin B12 and Vitamin E: To help utilize vitamin A efficiently.

6. Avoid Certain Foods: Foods like cabbages, radishes, mustard, peanuts, and soybeans can interfere with thyroid function, which can affect fluid balance. Cooking these foods can reduce their negative effects.

7. Use Progesterone: Progesterone can help reduce edema by increasing the binding capacity of albumin, which helps retain water in the blood vessels.

8. Exercise: Regular physical activity can improve circulation and help reduce fluid retention in tissues.

9. Adequate Sleep: Ensure you are getting enough sleep, as it helps the body to reabsorb excess fluid.

10. Manage Stress: Stress can affect liver function and protein synthesis, so managing stress through relaxation techniques can be helpful.

[cs3000]

@yerrag wild situation, and amazing that u bounced back from that extreme

Effect of coenzyme Q10 therapy in patients with congestive heart failure: a long-term multicenter randomized study
https://pubmed.ncbi.nlm.nih.gov/8241697/

• The improved cardiac function in patients with congestive heart failure treated with coenzyme Q10 supports the hypothesis that this condition is characterized by mitochondrial dysfunction and energy starvation, so that it may be ameliorated by coenzyme Q10 supplementation. However, the main clinical problems in patients with congestive heart failure are the frequent need of hospitalization and the high incidence of life-threatening arrhythmias, pulmonary edema, and other serious complications.
  randomly assigned to receive either placebo (n = 322, mean age 67 years, range 30-88 years) or coenzyme Q10 (n = 319, mean age 67 years, range 26-89 years) at the dosage of 2 mg/kg per day in a 1-year double-blind trial.
  The number of patients who required hospitalization for worsening heart failure was smaller in the coenzyme Q10 treated group (n = 73) than in the control group (n = 118, P < 0.001).
  Similarly, the episodes of pulmonary edema or cardiac asthma were reduced in the control group (20 versus 51 and 97 versus 198, respectively; both P < 0.001) as compared to the placebo group. Our results demonstrate that the addition of coenzyme Q10 to conventional therapy significantly reduces hospitalization for worsening of heart failure and the incidence of serious complications in patients with chronic congestive heart failure.

Case of edema + heart failure fixed by t3:t4 combo
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10329947/

• At 6 weeks after T3 and T4 administration, his heart function had noticeably recovered with a left ventricular end-diastolic diameter of 71.5 mm and LVEF of 35%, and his weight had decreased from 93.8 kg to 71.7 kg without pitting edema.

Case Report: Severe Edema and Marked Weight Gain Induced by Marginal Thiamine Deficiency in a Patient With Alcohol Dependency and Type 2 Diabetes Mellitus

Based on such findings, we think it is possible that severe edema in the whole body and significant weight gain were, at least in part, induced by thiamine deficiency itself, although he had various causes of fluid retention due to alcohol dependency.

{{mostlylurking breaks through the wall}}

• In addition, since we considered that the severe edema in the whole body and significant weight gain were, at least in part, caused by thiamine deficiency, we started fursultiamine hydrochloride (50 mg/once a day) for seven days. The plasma vitamin B1 concentration was increased to 853 ng/mL (reference interval: 24–66 ng/mL)

His body weight was decreased by 18 kg two weeks later and was 83.2 kg at discharge.

• His conditions of the heart, liver, and renal function did not substantially change during the period of exacerbation of his edema and weight gain. In addition, ALT, AST, creatinine, and BUN were rather increased mildly probably due to dehydration 12 days after admission when body weight was decreased (Tables 1, 2; Figure 3). Thereafter, his liver and renal function were gradually improved (Figure 3). These results suggest the possibility that the significant decline in body weight in this patient was, at least in part, attributed to the treatment of mild thiamine deficiency.

In addition [to the alcohol & hypo] , the long-term administration of the diuretic drug for heart failure may lead to thiamine deficiency through increased thiamine excretion

• prior studies have demonstrated that TD exerts an unfavorable effect on cardiac contractility in the long term, which can clinically manifest as heart failure.3-5 when there is an undernourished dietary history and chronic alcohol intake, physicians can reasonably suspect this disease

A Case of Cardiac Beriberi: A Forgotten but Memorable Disease

A 72-year-old female presented at our emergency department with 1-week febrile sense, progressive dyspnea, and generalized edema , intermittent abdominal pain localized to the right upper quadrant for four months. Peripheral oxygen saturation was approximately 100% without oxygen supplementation despite subjective dyspneic complaint

• with mild pulmonary congestion and pleural effusion (pleural effusion = fluid at bottom surrounding part of lung) ****pleural fluid is yellow

• intravenous thiamine administration was initiated for the next seven days, which was subsequently switched to oral vitamin B complex. With thiamine supplementation, the patient's condition steadily and gradually improved. Liver enzymes and total bilirubin were restored to normal levels a week later, and she was given permission to leave hospital two weeks after admission.

• Follow-up echocardiography performed six months later revealed that her cardiac condition had dramatically improved: LV end-diastolic dimension decreased from 70 mm to 61 mm with a concomitant increase in LV ejection fraction to 43%, systolic pulmonary artery pressure was significantly decreased to 38 mm Hg, and the pericardial effusion that was present before the initiation of treatment was gone (Fig. 3C and D). The patient's subjective complaints of dyspnea and generalized edema were also no longer present.

Note:
here someone with thiamine deficiency without alcohol intake had the edema fixed by thiamine, BUT it caused pulmonary edema in this case and diuretics had to be added with it to fully fix. because of the thiamine suddenly creating changes in vasoconstriction (why its best to take it slow with the dose unless are currently on diuretics) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028406/

@razvan yeh, i think its common to just drink it for its own sake as a default. i did until recently and noticed its very easy to tip over to clear urine with a small amount of water in hypo, & increase adrenaline

[Mr. X]

My Mum is hospitalized since 2 months ive been there every day for couple of hours.

She had/has:

-Pneumonia
-water in the lungs and body
-fever
-need for an oxygen machine
-Heart valve inflammation, but is back to half of the inflammation after 6 weeks of 3 different antibiotics 6 times per day IV
-COPD (was already before but nothing crazy)
-2-3 little strokes
-atrial fibrillation in the heart (endocarditis)
-stomach inflammation now put on PPI
-black stool (gastroscopy found nothing)
-loose stool since starting of the antibiotics
-kidney dialysis started today

-shes getin lasifix to get the water out of the body and potassium nearly daily.

Many things above are resolved and is goin in the right direction, after 2 months. But what scarest me the most and what is getting worser every day since 1-2 weeks. She has problem finding words, cant speak probably I cant nearly understand nothing what she is sayin. And her memory is almost gone. She is confused.

I want to do anything for her, can some of you put me into a direction with the speaking, memory, confused etc. What should I look for vitmans? minerals? Electrolytes? Glucose in the brain is missing? Dextrose ? B1? Prog? T3?

[yerrag]

@Mr-X

Having been in the ICU and treated for heart failure, as well as having taken care of both parents in their twilight, with their recurring hospital admissions in their twilight before they passed, I can offer some observations that may help you that is separate from the supplementation which you will usually get in this forum.

One is that your mom is likely to be in an acidic situation. The stresses she has undergone and the treatments she is getting likely gets her system to be very acidic. One way you can tell is if you ask an attending nurse, her breath rate is likely to be way above 14 or minute, and the higher above it, the more acidic her condition is. Her heart rate would be high because the acidic state she's in causes the body to compensate by releasing potassium for her cells to the blood while drawing hydrogen ions in her blood to her cells, in an effort to reduce the acidity (potassium being less acidic than hydrogen ions). Because of this, the cell loses its role thru potassium in regulating calcium into the cell. So much so that the needed graident in cellular calcium to extracellular calcium is lessened, and this causes muscles to lose its ability to contract and to relax as efficiently. The heart being a muscle, would also be strained and inefficient in pumping blood, and this causes it to pump more, and this is why the heart rate increases.

Sorry if I can't explain the above much more simply and in a shorter way, but the net of it is that she is very acidic extracellularly (blood and the extracellular fluids) and what makes it worse is that she is low in CO2, which is the main pH buffering agent of the body, as CO2 readily converts to acid (carbonic acid) and to a base (bicarbonate) depending on the pH state of the body at any given time and how much it deviates from the ideal pH of the body.

At her condition now, her body does poorly in regulating pH thru the lungs and the kidneys. Her lungs are in the process of healing, and is likely to do a poor job regulating pH.

And she is likely, at her state, running on a low metabolic pathway of glycolysis and producing lactic acid instead of CO2. It doesn't help that her blood is low on CO² already and this gets in the way of good tissue oxygenation, which sets her body with no choice but to run on glycolysis.

A way out of this dilemma of a vicious cycle is to provide your mom with exogenous sources of CO2.

In a hospital setting, breathing carbogen is banned so that option is put. What would help is to give her magnesium bicarbonate to drink. This might be frowned upon by the doctors and nurses, but you can do this easily as magnesium bicarbonate looks like water- transparent.

Why this is helpful is that magnesium bicarbonate is easy to drink and it contains plenty of bicarbonate- what your body needs to counter the acidic ecf. It will also improve the tissue oxygenation of your tissues, by increasing the CO2 in your blood to allow blood to release the oxygen your tissues need so much right now.

And did I say your brain needs this even more? It is probably why your mom is now having brain issues because of the lack of oxygen getting into your brain.

To make magnesium bicarbonate, go to:

https://drdavisinfinitehealth.com/2020/05/magnesium-water-step-by-step/

The RDA for magnesium is 400 mg elemental magnesium per day. Depending on how your mom takes to it, she can have as much as 800-1000mg, on a therapeutic basis. See if she can handle it, as the risk is small with possible diarrhea (bit I doubt thst would happen unless she is doing this on a long term). There is no toxicity of magnesium overload, as the body would excrete it via diarrhea if that happens, but chances are your mom is deficient, as most people are.

[yerrag]

@yerrag said in Edema with water logged lungs / heart atrial fibrillation / pleural fluid around the lungs - approach to fix:

@Mr-X

Having been in the ICU and treated for heart failure, as well as having taken care of both parents in their twilight, with their recurring hospital admissions in their twilight before they passed, I can offer some observations that may help you that is separate from the supplementation which you will usually get in this forum.

One is that your mom is likely to be in an acidic situation. The stresses she has undergone and the treatments she is getting likely gets her system to be very acidic. One way you can tell is if you ask an attending nurse, her breath rate is likely to be way above 14 or minute, and the higher above it, the more acidic her condition is. Her heart rate would be high because the acidic state she's in causes the body to compensate by releasing potassium for her cells to the blood while drawing hydrogen ions in her blood to her cells, in an effort to reduce the acidity (potassium being less acidic than hydrogen ions). Because of this, the cell loses its role thru potassium in regulating calcium into the cell. So much so that the needed graident in cellular calcium to extracellular calcium is lessened, and this causes muscles to lose its ability to contract and to relax as efficiently. The heart being a muscle, would also be strained and inefficient in pumping blood, and this causes it to pump more, and this is why the heart rate increases.

Sorry if I can't explain the above much more simply and in a shorter way, but the net of it is that she is very acidic extracellularly (blood and the extracellular fluids) and what makes it worse is that she is low in CO2, which is the main pH buffering agent of the body, as CO2 readily converts to acid (carbonic acid) and to a base (bicarbonate) depending on the pH state of the body at any given time and how much it deviates from the ideal pH of the body.

At her condition now, her body does poorly in regulating pH thru the lungs and the kidneys. Her lungs are in the process of healing, and is likely to do a poor job regulating pH.

And she is likely, at her state, running on a low metabolic pathway of glycolysis and producing lactic acid instead of CO2. It doesn't help that her blood is low on CO² already and this gets in the way of good tissue oxygenation, which sets her body with no choice but to run on glycolysis.

A way out of this dilemma of a vicious cycle is to provide your mom with exogenous sources of CO2.

In a hospital setting, breathing carbogen is banned so that option is put. What would help is to give her magnesium bicarbonate to drink. This might be frowned upon by the doctors and nurses, but you can do this easily as magnesium bicarbonate looks like water- transparent.

Why this is helpful is that magnesium bicarbonate is easy to drink and it contains plenty of bicarbonate- what your body needs to counter the acidic ecf. It will also improve the tissue oxygenation of your tissues, by increasing the CO2 in your blood to allow blood to release the oxygen your tissues need so much right now.

And did I say your brain needs this even more? It is probably why your mom is now having brain issues because of the lack of oxygen getting into your brain.

To make magnesium bicarbonate, go to:

https://drdavisinfinitehealth.com/2020/05/magnesium-water-step-by-step/

The RDA for magnesium is 400 mg elemental magnesium per day. Depending on how your mom takes to it, she can have as much as 800-1000mg, on a therapeutic basis. See if she can handle it, as the risk is small with possible diarrhea (bit I doubt thst would happen unless she is doing this on a long term). There is no toxicity of magnesium overload, as the body would excrete it via diarrhea if that happens, but chances are your mom is deficient, as most people are.

[yerrag]

@Mr-X

Also, thiamine would help. It would lower the lactic acid levels. As I understand it, it would make it possible for lactic acid converted to glucose, thus lowering lactic acid levels in blood. This would allow more CO² to be in the blood, and thus improve tissue oxygenation.

If you can ask to have around 1000mg daily via IV, your doctor would know that this is SOP in ERs and agree to it.

[Razvan]

@yerrag Is there anychance sodium bicarbonate could do the same?

[yerrag]

@Razvan said in Edema with water logged lungs / heart atrial fibrillation / pleural fluid around the lungs - approach to fix:

@yerrag Is there anychance sodium bicarbonate could do the same?

It can, but it is harder to take. For the patient, mag bicarb is like drinking water.

[yerrag]

@yerrag

It is much better to get some some magnesium than sodium while at it.

[yerrag]

@Razvan said in Edema with water logged lungs / heart atrial fibrillation / pleural fluid around the lungs - approach to fix:

@yerrag Is there anychance sodium bicarbonate could do the same?

Magnesium also calms the brain. It will keep neurons from energy failure when there are excitotoxic effects coming from some drugs prescribed by doctors, who are often unaware or choose to be oblivious to such side effects. The drug would cause neurons to get so excited and it would lead the neurons to use a lot of energy from being excited, and when no energy can. e supplied, the neurons could die and this would lead to a coma.

I once gave my mom a food blend that had magnesium in it. She was near a state of coma but could still be spoonfed. The neurologist told me my mom would likely have to go to a hospice to slowly die. But with the food, she slowly emerged from a near comatose state to being able to walk out of the hospital upon discharge. That is why magnesium is so important.

[Mr. X]

@yerrag nice story and thanks for your help.
I gave my mom today a multivitamin/mineral capusle nearly everything in it u can imagine with all of it nearly 100% of RDA. Than I gave her 250mg Thiamine HCL, 150mg benfothiamine, 450mg magnesiumbisglycinate all orally and vitamin d in mct oil topically on her legs. Within a couple of minutes her eyes got more wide open, she could speak better and also menory was better but than i think the energy boost gave her hyperventilation she couldnt retain the co2 she started sweating and put nearly all clothes off and she said she is getting a panic attack. My magnoil is empty i must order a new bottle, this would be perfect to rub on her body. I had also energin with me but was scared that someone saw the yellow residue from the b2. I think tmrw i half the dose on the thiamine hcl and benfo and everything else the same.

She said by herself after i gave everything to her today that its a little bit better finding the words and speak better. I was so sad to put her in the bad situation with the hyperventalation and panic attack

The kidney dialysis since 2 days fucks her up big time she is so weak since the start but i think the regime above will help her in the long run

[yerrag]

Glad to see your mom feeling better.

[Mr. X]

@yerrag thanks a lot for your help. I will achieve the same with my mother like you did. She didnt walk for over 2 months but we‘ll left the hospital on her feet soon.

Today I gave her:

1x multi/mineral capsule with everything 100%RDA
1x thiamine HCL 125mg
1x benfothiamine 75mg
1x squeeze of vitamin d topically on her legs in mct oil
5x drops of energin (haiduts b complex) topically on her leg
1x 450mg mag bisglycinate

So I cut the dose on half for thiamine HCL, benfothiamine and vitamin d.

Today she is fine without the hyperventalition and panic attacks, even after half an hour 2 different nurses also said you looking better, you can speak better and and your mind is clearer.
And she said by herself her mind is clearer.

I think I overdid it with the B1 yesterday from zero to hundred too fast.

Now she is asleep, I‘m so happy

[yerrag]

@Mr-X Very nice!

[Mauritio]

@yerrag Happy you survived man !