The Incretin Effect of Yerba Maté (Ilex paraguariensis) Is Partially Dependent on Gut-Mediated Metabolism of Ferulic Acid
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Yerba maté (YM) is a traditional herbal beverage made from Ilex paraguariensis. It contains bioactive compounds like polyphenols and alkaloids known for their metabolic benefits. This study investigates YM’s incretin effects, focusing on glucagon-like peptide-1 (GLP-1) and gastric inhibitory polypeptide (GIP)
Results: YM supplementation significantly increased GLP-1 gene expression and plasma GLP-1 levels compared to controls, with no changes observed in GIP expression or plasma levels. Direct treatment of GLUTag L-cells with YM did not enhance GLP-1 secretion. However, dihydroferulic acid, a microbial metabolite of ferulic acid, markedly stimulated GLP-1 production in L-cells, highlighting a role of gut-mediated metabolism in YM’s incretin effects.
Conclusions: YM selectively upregulates GLP-1 pathways without affecting GIP, likely through gut-mediated mechanisms. These findings suggest YM as a promising nutraceutical for incretin modulation and metabolic disorder management. Further studies should explore the interplay between YM, the gut microbiota, and incretin pathways to fully realize its therapeutic potential. -
@DavidPS there's a guy on rpf that is convinced a Yerba mate drink in Argentina poisoned him and now he basically wants to go on a murderous religious rampage and is trying to convince others to join him
the name of this blog is modern procer. he posts once in awhile
here is an excerpt:
"We have to go with realistic expectations, understanding that because of the social engineering carried out in the years past, many people did corrupt themselves to a level there is no turning back. If one presenting solutions is attacked by the ones that don’t want to leave their sexual immorality, their frauds, or vices against nature, one will see no other but to begin a purge.
Precisely, the purge is necessary to put an end to the genocide that was already taking place.
The standards are understood like aspiring to have sex only in marriage, to live in decency, and that one be caring about his neighbor."
I read one of his comments somewhere that he sees the indigenous population of Argentina / S.A. as inferior lol
he is a balding skinny guy btw and last I checked father to a child he is not in the life of.
should people like this be mocked ?
totally not a thread derail btw
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@sushi_is_cringe
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@Otto there is zero information on that blog to be found about potential contamination of Yerba mate, just about how to commit genocide in response to genocide. I asked the dude for some sort of proof or anything and didn't get a response
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@sushi_is_cringe
yerba mate bros... our response?
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of course now im classified as a psychopath according to him
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niggas can't even keep their own house in order and they wanna go out there and purge society in violent revolutions... wash ur penis, bucko
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any man against tank tops is obviously fundamentally evil
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He also has a curious obsession with hemodialysis.
Light mockery is fine I think, obviously. Just decode what you're mocking, lest ye become the mocked.