High-Fat Diet Triggers Memory Decline Within Days

Kvirion

Via Neuroscience News - in your face ketards

High-Fat Diet Triggers Memory Decline Within Days

A new study reveals that just three days of consuming a high-fat diet can trigger memory problems and brain inflammation in older adults, independent of obesity.

Researchers observed that aged rats fed a diet with 60% of calories from fat exhibited rapid cognitive decline, while younger rats remained unaffected.

Metabolic issues and gut health changes took longer to develop, suggesting that diet-related brain inflammation occurs before other health effects.

The memory deficits were linked to increased inflammatory markers in the hippocampus and amygdala, two key brain regions for memory and emotion.

This study challenges the assumption that diet-induced brain inflammation is primarily driven by obesity.

The findings highlight the vulnerability of aging brains to unhealthy diets and underscore the importance of nutrition in maintaining cognitive health.

Source: https://neurosciencenews.com/high-fat-diet-memory-aging-28469/ + https://x.com/NeuroscienceNew/status/1897761324693852345

teenus

@Kvirion Interesting, do we know what fat these rats were being fed?

Kvirion

@teenus Good point

So, high-fat diet: 18.3% calories from protein, 21.4% from carbohydrates, and 60.3% from fat (36% SFAs, 41% MUFAs, 23% PUFAs)

Full research paper https://immunityageing.biomedcentral.com/articles/10.1186/s12979-024-00496-3

bot-mod

@Kvirion said in High-Fat Diet Triggers Memory Decline Within Days:

Via Neuroscience News - in your face ketards

This may be the therapeutic they're actually after.

Milk Destroyer

@ThinPicking Just forget it all bros...

Corngold

@Kvirion

gotta wonder what the result would be if it was 90% saturated fat instead of 36%.

jamezb46

@Corngold

My thoughts exactly. This is one of the most nefarious tricks of "high fat diet" studies. Almost all of them are high PUFA. 23% of calories from PUFA is unbelievably high. In a human eating 2300 kcal, that would be 53 GRAMS of PUFA per day.

I usually get about 2-3g per day for context. You will find the same gaslighting when it comes to studies "showing" that high saturated fatty acid diets cause inflammation. All of those "high SFA" diets are confounded by PUFA.

Kvirion

@ThinPicking said in High-Fat Diet Triggers Memory Decline Within Days:

This may be the therapeutic they're actually after.

Yeah, right - to some extend, if fats were all saturated.

Kvirion

@jamezb46 said in High-Fat Diet Triggers Memory Decline Within Days:

I usually get about 2-3g per day for context. You will find the same gaslighting when it comes to studies "showing" that high saturated fatty acid diets cause inflammation. All of those "high SFA" diets are confounded by PUFA.

Good point. But only a few look under the hood of such studies...

@Corngold

gotta wonder what the result would be if it was 90% saturated fat instead of 36%.

It should look better, but it is still far from perfect. 60% fat is not a healthy amount... I guess.