Chemotherapy recovery & Narcolepsy - please advise
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Chemo for what cancer at eleven Meursault?
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@Meursault said in Chemotherapy recovery & Narcolepsy - please advise:
I'm very motivated and mentally energised, but feel trapped in a physical state that can't keep up.
A little manically so?
I get cataplexy, where I lose control of my muscles momentarily sometimes.
Along with the somnolence, electrolyte disturbance probably. imo
All food and fluid behaviour in great detail by TOD please. If you can't do this for irregularity, that's step one. Routine.
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@ThinPicking Leukemia age 11.
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Sorry you went through that. How was your sense of your health in the years leading up to it?
@Meursault said in Chemotherapy recovery & Narcolepsy - please advise:
I feel as though I'm trapped in...
You'll drill the lock.
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@ThinPicking said in Chemotherapy recovery & Narcolepsy - please advise:
All food and fluid behaviour in great detail by TOD please. If you can't do this for irregularity, that's step one. Routine.
Left job last month and eating well since then and gained some weight. I can't say I had any regular pattern before now though. would eat one meal all day often and it was just when we had time. Also wouldn't drink much water. then try make up for it on days off.
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@ThinPicking said in Chemotherapy recovery & Narcolepsy - please advise:
How was your sense of your health in the years leading up to it?
Couldnt have been in better health. physically fit, ate well, etc.
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@Meursault said:
my hormones are tanked along with my immune and mitochondrial health. I feel as though I'm trapped in some sort of autoimmune state.
If that's some kind of pseudo-autoimmune issue from actually compromised immune-functions along with mitochondrial dysfunctions look into each stage of the mitochondrial respiratory complex.
Maybe start with complex IV and push CoA and cysteamine by 600-1200mg oral pantethine (not pantothenic acid) daily for at least two weeks. Could be $30 well spent to trial.
If your hypothalamic and pituitary glands are functional that slightly elevated TSH may be a hint to impaired liver function.Also, strong doubts anybody's going to adequately thank you for doing 90hrs/week. Mostly those jobs with such extra hours are stone-cold extortion shrouded in empty promises.
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@CrumblingCookie said in Chemotherapy recovery & Narcolepsy - please advise:
Also, strong doubts anybody's going to adequately thank you for doing 90hrs/week. Mostly those jobs with such extra hours are stone-cold extortion shrouded in empty promises.
Sound advice. That's always going to be for the wrong boss. Small b.
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@CrumblingCookie said in Chemotherapy recovery & Narcolepsy - please advise:
Also, strong doubts anybody's going to adequately thank you for doing 90hrs/week. Mostly those jobs with such extra hours are stone-cold extortion shrouded in empty promises.
for sure. I became addicted to the work and the constant adrenaline state. it becomes a vicious cycle.
Looking into the ETC, feels like there is a block somewhere. Reading that when ATP stores decline, orexin neurons cease firing causing the sleep issues. reduced function here then most likely exacerbated the adrenaline/ cortisol response.
Liver markers (Bilirubin, ALP, ALT, GGT) all came back within range is there something missing there? find it hard to imagine my liver is in great health.
there could be an issue with hypothalamic (the narcolepsy itself may indicate improper function) although unsure whether this would be affecting TSH directly. It did feel that 'wasteful energy' production was causing improper signalling and over-excitatory responses eg the cataplexy.
could a combination of high dose B vitamins address some of these issues? T3?
Looking to first do what i can do reverse any stress state I'm in. -
@Meursault said:
would eat one meal all day often and it was just when we had time. Also wouldn't drink much water. then try make up for it on days off.
That's not how sufficient drinking and good homeostasis of bodily fluids and electrolytes works btw.
If you are on of those people who simply don't drink water because they forget and/or because it tastes boring I don't know how that can be taught.@Meursault said:
Liver markers (Bilirubin, ALP, ALT, GGT) all came back within range
That never excludes functional liver issues. It simply means whatever's going on is not killing the liver cells very much.
Since I've currently been reading up on B5 pathways ("hammer") everythings looks a nail to me as in lack of B5 causes strong somnolence, irritability, insomnia. Its transport protein also carries biotin and iodide into all bodily tissues hence there's a lot of possibilities wrt wakefulness, energy and endocrine and thyroid hormone secretions.
Depending on the parameters range of the urinary organic acids test you have ordered there should be a lot of insight to be gained about which steps of the TCA aren't running well enough. E.g. elevated lactic/pyruvic/3-hydroxyvaleric/-propionic/oxalic/xanthurenic acid etc.
Will be interesting to see what that shows.
