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Androsterone and acne

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  • L
    Living_thing
    last edited by Jun 12, 2025, 2:39 PM

    Hi everyone. I tried a drop of androsterone ~1mg, 3 times. Each time it cause spots full of sebum to appear around my left ear. Like raised lumps that sebum came out of if I scratched them.
    Anyone else had similar results or knows why this happened?

    S 1 Reply Last reply Jun 13, 2025, 5:53 AM Reply Quote 0
    • S
      sunsunsun @Living_thing
      last edited by Jun 13, 2025, 5:53 AM

      @Living_thing I have gotten that kind of thing when losing fat
      maybe its estrogen being expelled

      L 1 Reply Last reply Jun 13, 2025, 6:45 PM Reply Quote 0
      • 1
        16characterstwas
        last edited by Jun 13, 2025, 2:09 PM

        Post in thread 'Ray Peat Email Advice Depository'
        https://lowtoxinforum.com/threads/ray-peat-email-advice-depository.1035/post-285682

        Wagner: "Hey , I'd like to know what do you think about 11-keto-dht, does the addition of the ketone group makes it more toxic? Half life is longer which sounds like a good idea, it is naturally present in the body and a strong androgen. By the way there is this paper ( Feed-forward control of prostate growth: dihydrotestosterone induces expression of its own biosynthetic enzyme), on how dht stimulates its own synthesis.."

        Ray: "I think it’s risky to supplement hormonally active intermediates in steroid metabolism, since it can have widespread unexpected effects.

        W: "Ok thanks, I thought dht and 11-keto-dht were end point steroids (Hans selye work on combining upstream and end point steroids is interesting) , does that mean you would not supplement with androsterone either?"

        R: "I think I might use DHT, but not androsterone or the ketos."

        L 1 Reply Last reply Jun 13, 2025, 6:46 PM Reply Quote 0
        • L
          Living_thing @sunsunsun
          last edited by Jun 13, 2025, 6:45 PM

          @sunsunsun that could be why. Thanks

          1 Reply Last reply Reply Quote 0
          • L
            Living_thing @16characterstwas
            last edited by Jun 13, 2025, 6:46 PM

            @16characterstwas right. I remember that. Thanks

            1 Reply Last reply Reply Quote 1
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