Aspirin provokes gyno flare-up?

[deliciousowl]

I've noticed that against all logic (aspirin as an aromatase inhibitor, etc), whenever I take even 300mg it causes a gyno flare-up for about a day. I saw that this question was asked in the previous forum, but no real answer was found. Anyone know why?

This occurs whether or not I take my "anti-estrogen" stack:

• 1.2mg Vitamin K2
• 3000 IU Vitamin D
• 10,000 Vitamin A
• 400 IU Vitamin E
• 50mg pregnenolone once a week

[NangaParbat]

@deliciousowl Does it also give you low blood sugar? Mb try pairing it with some fruit juice to see if the effect persists. You should also check for a change in temperature after taking it, as this can reveal what physiological state you are currently in. If temperature drops as a result of taking aspirin, then a generous serving of salt, calcium carbonate, or bicarbonate are avenues to explore.

[deliciousowl]

@NangaParbat I always take it with orange juice, so it's not that. I will try the calcium. out of curiosity What's the logic behind adding the calcium/sodium?

[NangaParbat]

@deliciousowl Prolactin increases sodium secretion. Calcium carbonate to probe intracellular calcium, since parathyroid hormone can increase prolactin just getting enought calcium might make the difference.

"Calcium carbonate (eggsheil or oyster sheil, fOf exampie)· and
vitamins D and K, can sometimes produce quick antistress effects, alleviating insomnia, hypertension, edema, inflammations and allergies, etc. " Milk in context Peat

[mnemosyne]

You are probably looking at an estrogen clearance problem. The body using up its resources clearing out the aspirin.
Also eliminate as many plastics as possible.

Would take break from all sups, really. If a sup doesn’t do anything with one or two doses, you most likely don’t need it. Something else messing with the cell environment.

[deliciousowl]

@mnemosyne I take long breaks from supps, and have avoided pregnenolone and vitamin A, as well as K2 for months.

I unfortunately cannot drop D & E due to extremely low blood levels of D, and E due to slightly raised estradiol and prolactin levels.

I imagine something to help liver clearance like milk thistle would be useful? Or are there ways to measure what the problem could be?

[thebodyelectric_]

@deliciousowl I think @NangaParbat comments spot on

[deliciousowl]

@thebodyelectric_ @NangaParbat yes it was 1000% correct! I did a bloodtest and had borderline hypocalcemia. Absolutely spot on you guys are legends

[mnemosyne]

@deliciousowl things about it is, only one metabolite is measured on a D test. It's a steroid with multiple metabolites with varying degrees of solubility. Until you look for every other metabolite in both blood and organs, you cannot really conclude yourself to be having an actual deficiency.
If you really believe you need E, I would rather just stick with olive oil. Ray wrote about the benefits of oleic acid too.