Tianeptine
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If Tianeptine is the only thing that makes you not depressed and you really need an anti-depressant, talk to a "doctor" and get amitriptyline. Tricyclic antidepressants (TCAs) like amitriptyline do similar things to Tia but it's a lot safer, even though all Tricyclic antidepressants cause fatal heart attacks around 40 (including Tianeptine) if used regularly.
The fact you write this stupid crap makes me dislike you. You're lucky this forum doesn't allow making violent threats.
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@iHateTheBlacks Amitriptiline is a SNRI. Please never respond to my threads again.
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@thyroidchor27 you're completely wrong here bud.
It's one google search away.
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@Bleach_Africa
"Amitriptyline acts primarily as a serotonin-norepinephrine reuptake inhibitor, with strong actions on the serotonin transporter and moderate effects on the norepinephrine transporter . It has negligible influence on the dopamine transporter and therefore does not affect the reuptake of dopamine , being almost 1000 times weaker than serotonin on it. It is metabolized into nortriptyline , a potent and selective norepinephrine reuptake inhibitor , which can complement its effects on norepinephrine reuptake."
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@Bleach_Africa said in Tianeptine is the most wonderful drug Ive tried:
I've withdrawn from just about every drug. Tianeptine Sulfate withdrawal after just 10 days was by far the most traumatic withdrawal I've ever had. I had Kratom, gabapentin, and clonazepam to help ease me through the withdrawal. For 9 days I laid in bed. The first 5 days I was crying for no reason, sweating, pooping out acid.
I've withdrawn from hardcore benzo usage after 6 years, and that was much milder (though much longer) than Tianeptine Sodium withdrawal, and I had tons of other things to help ease and get me through Tianeptine Sodium withdrawal and NOTHING to ease me through a 6 year 6mg a day
Did you stick to the 10 mg x 2 per day dosing on tianeptine sodium? Cause I know of 0 people who have had any sides on that dosage except perhaps insomnia, constipation and a general worsening of mood. People who get these withdrawals take it recreationally at 1g plus. These people are mentally ill. Even going above 30 mg is asking for trouble, like I said it has a narrow safety profile and if you arent down with that then dont do it lol
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@thyroidchor27 of course I didn't, I was very mentally ill and it was just a great way to pass the time during the quarantine.
It can easily give you an ulcer as well, at the end day 6 of my binge I had a sharp pain in my stomach that went away about 2 weeks after I quit.
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Ssecond time trying it without selegiline and all the sides avoided. The MAO I was definitely interacting somehow with it causing me chest pains.
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@thyroidchor27 have u been continuing?
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Not on the days where I take a microdose of selegiline in the morning, the MAO I somehow greatly prolongs the effect of the tianeptine sodium and although im not complaining about the effects, this prolongation causes insomnia,
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There are slightly looser stools due to the opiate effect.
Barring these two, its a God tier drug. Very underrated in the Peat sphere, although narrow therapeutic potential. Never go above 12.5 mg, and Imo just dosing 6 mg twice a day is probably enough because the binding affinity is very high for this drug for all sero, dopa, and mu opiod receptor.
I think just a month on it every other day will be great. But should be discontinued, and resumed every 5 months or so if the need arises. Great for when stuck in a dull routine, for enjoying movies, opening up perspectives, increasing socialisation experiences, mood lift etc etc, basically all the high sero / low dopamine expereinces. And although opiods are not Peaty, I think this combination is great for immediate mood lifts which while low sero also encourages is potentiated by the slight MOR agonism.
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@thyroidchor27 I often suggest people take 25mg twice a day for depression and it works very well with no side effects that I've noticed at all.
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I really liked Tianeptine but when I did a blood test my testosterone was HALF of my levels when sober. From 700 to 350. Went back to normal after I quit.
Also, I don't agree with the withdrawal scares in this thread. If you take the usually prescribed dosage of 3x 12.5mg a day, you will not have strong withdrawals at all.
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@deliciousowl yes its opiod. I think even that is too much I never go above 12 mg a day and I only use it three times a week. serotonin is generally androgen inhibitory and I dont think the opiod agonism outweighs the pro sero- inhibitors effects on T at that dose
