my recent subhuman bloodwork for recurring nausea/anxiety

yerrag

I'm trying to make sense of why your triglycerides are below reference range. It's either a liver problem or you're not making enough insulin. Since your liver looks ok (based on your AST and ALT enzyme test results), Insulin signals your liver to convert blood sugar to triglycerides, and a lack of insulin secretion from the pancreas could keep the liver from getting the signal to convert blood sugar to triglycerides.

But I am not sure as your blood sugar is not so high. It is only milldly high, and so it's possible you are metabolizing sugar well enough or that you're not eating enough carbs such that your intake of sugar/carbs is such that your sugar metabolism is not really put to the test. Are you on low carb, or keto, or carnivore diet or doing intermittent fasting? As using these methods are a poor substitute to deal with having a faulty sugar metabolism.

@yerrag said in my recent subhuman bloodwork for recurring nausea/anxiety:

@mostlylurking said in my recent subhuman bloodwork for recurring nausea/anxiety:

Could you rephrase the above paragraph? I'm having a hard time understanding. What is being taken in possibly too high a dose? Or did you mean to say the thiamine dose was too small?

My brain and typing coordination had a miss (I wonder if there is a pathology to this. Happens to me too often). Sorry. I'll rephrase:

Last week I discovered I was thiamine insufficient, even with my thiamine daily dosage being high (at
250mg) relative to rda. Just like me, you may just need more thiamine. In my case, I had to increase my dosage to 1500mg. You could be either thiamine deficient (below rda) or thiamine insufficient ( above rda but still lacking in thiamine intake).

@mostlylurking Thanks for adding your thoughts and references. I could use them also.

You're welcome. I'm glad to try to help out. FWIW, I think your writing/typing has improved recently. Maybe it's the additional thiamine....

Hando-Jin

@the-MOUSE

I dealt with nausea for long periods of time. It made me want to punch holes in walls.

After trying everything, thyroid was the thing that took it away and there was good reason for that, so you could consider thyroid.

Absolutely consider cypro also, given its got good evidence behind it for cyclical vomiting syndrome etc

the MOUSE

@yerrag thank you very much again for this very insightful response

@yerrag said in my recent subhuman bloodwork for recurring nausea/anxiety:

This relationship becomes disturbed when our body becomes very acidic and this is when our blood potassium becomes very high in potassium, which is our body's attempt to move potassium from its cells to its extracellular fluids, as reflected in plasma. Then the doctor will see that and tell us we have "too much potassium." And now we know that is nonsensical because we know better now. But in fairness to the doctor, he will just be exasperated explaining this to the average person.

yup, i had slight hyperkalemia in the past as well with accompanying high anion gap of 19. doctor just said lower cocnut water, bananas etc when i wasnt even consuming muhc potassium in diet. they were oblivious and overlooked acidosis. iron saturation was 27% but i think mayve improved as of recent as was 1 yr ago.

@yerrag said in my recent subhuman bloodwork for recurring nausea/anxiety:

But I am not sure as your blood sugar is not so high. It is only milldly high, and so it's possible you are metabolizing sugar well enough or that you're not eating enough carbs such that your intake of sugar/carbs is such that your sugar metabolism is not really put to the test. Are you on low carb, or keto, or carnivore diet or doing intermittent fasting? As using these methods are a poor substitute to deal with having a faulty sugar metabolism.

i unwittingly intermittent fast, low carb sometimes due to low appetite and nausea. esp of recent this has been exacerbated. mayve affected this recent blood test too, days prreceding this blood test i would have only 1-2 meals a day rlly. even today i could eat very little, which then in a negative feedback loop caused me to vomit out the little i did eat. im recovering rn just thru mix of salt/sugar drinks. today i tried BRAT diet for nausea as was especially nauseous and low appetite eating just banana, 2*20g pea protein, 500-1000g salt drinks throughout day, 2 slices bread, carrot salad with coconut oil i still vomited. but in part i think psychological factors could be playing significantly as well in addition. think i notice these especially spur up when i feel high serotonin, low t, anhedonic. rn trying meditation for that i guess.

also another thing is i usually wake with a white/green coating on back third of the tongue. think it could be due to my diet which rn is like oats with cocoa powder, extra virg olive oil, banana in morning eaten slowly like 1-2hrs. i eat slow due to nausea and in general im just unable to eat quick. i think fibre in morning helps me, i vomit if i have plain orange juice/milk in morning. then sugar/pea protein drinks throughout day, lunch/dinner of rice with fatty gelatinous lamb, extra virg olive oil. on days im nauseuous ill usually just have liquid meals of sugar/protein every few hrs until it settles a bit around later in day and eat rice/lamb.

thiamine ill improve through nutritional yeast flakes i think. yeah i dont think i consumed much of this.

ill heed your suggestions and update how it goes. ill be visiting the doctor in around 4 days, ill try to suggest to him this could be due to acidosis, than him suspecting just anxiety and prescribing ssri.

doing some self research i think ye it seems to be lactic acidosis
https://en.wikipedia.org/wiki/Metabolic_acidosis#Causes

treatment they dont suggest much apart from taking bicarb
https://en.wikipedia.org/wiki/Lactic_acidosis#Treatment

looking at causes could maybe give more insights to treatment methods, fixing underlying causes. like ye it lists thiamine deficiencies as you stated, Impaired delivery of oxygen to cells is interesting too, i mayve unwittingly induced this from butekyo
https://en.wikipedia.org/wiki/Lactic_acidosis#Causes

the MOUSE

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the MOUSE

@Hando-Jin
thank you, ive considered cypro but that lowers hgh and i want to take hgh peptides soon for possible late puberty masculiniation. ik its bad in short term, but im seekign to care about longevity etc after this first.

also heard cypro long term can have side effects. think itd be better for me to solve underlying issue acidosis causing this nausea rn.

rn i think maybe consider ondanesteron, Promethazine( esp this could help high ige maybe too) instead. @thyroidchor27 thoughts on Promethazine? i promptly got the idea from here of Antihistamines with antiserotonergic activity section. idk much bout this tho, maybe serotonin antagonists can have rebound/effects from long term use
https://en.wikipedia.org/wiki/Serotonin_receptor_antagonist#Antihistamines_with_antiserotonergic_activity
https://raypeatforum.com/community/threads/otc-anti-histamines-with-anti-serotonin-action.8588/#post-976641

definitely agree i got to ameliorate my current suboptimal thyroid. i think i can do it through addressing this underlying issue first before exogenous t3 maybe. but even so, yeah it could be quite beneficial to start t3 now

yerrag

@the-MOUSE

I think all I can do for you is to try interpreting your blood test results. I have the feeling that I don't have the complete picture and your doctor knows enough of your history and you're right in having to check with your doctor what you learn from me. I hope he would consider what I've shared with you though chances of that happening are slim. Perhaps if you went to a another doctor and the doctor told you the same thing I did, and you told your doctor you have a cousin who is a doctor overseas and that he gave you some suggestions, your doctor would be more receptive as he won't feel insulted you asked for a second opinion, and he would be more open to considering what you share with him.

But I'm still lacking a lot of information on your history and your use of substances in the past such as psychiatric drugs that altogether make your condition what it is now. Filling that gap is hard. For example, I don't know what led to you becoming nauseous. I also wonder how SSRIs got into picture and whether you have been a long time user of SSRIs.

I would make no attempt to second guess your doctor. It is bad enough if your treatment is hampered by having so to speak too many cooks that spoil the broth. If you stsy with your doctor, you must have confidence in him enough to keep on being treated by him. If you think he has not diagnosed you satisfactory, then you have to consider whether to see another. Although that is easier said than done as most patients cannot discern whether their doctor is a good one or not. My sister, for example, likes a doctor because he is very bubbly and friendly and I wonder if competence ever came into the picture. Then again, it is hard to differentiate a Big Mac from one Mickey D branch to another.

What I'm in effect saying is that it would be difficult for me to help you if I have an incomplete understanding of your context. If your intent is to simply be to have your blood work interpreted, I hope I have been able to do that satisfactorily.

the MOUSE

@yerrag completely understandable yeah its very different over internet text than in person with medical records etc. nontheless youve provided very good inisghts im grateful for and will bring up. i think it could very well be tied with this too, ive had lindsays nails for a substantial period now https://bioenergetic.forum/topic/266/do-you-have-lunula-on-nails/3?_=1708866810091

thats a good suggestion, to say family doctor from overseas told me this. ive never been on ssri, he just prescribed zoloft as he thinks its due from anxiety, without consideration of other underlying issues like acidosis indicated by anion gap etc. only real significant past medication id say was antibiotics and probiotics.

ill try ameliorate this with him and post further results if needed, maybe i could request more specific tests that can provide further insights.

the MOUSE

@yerrag hey, just updating on my situation. its gotten quite better as of recent. i think it was acidosis due to respiratory acidosis( i used to do butekyo and that gave me the habit of short inhalations with small volumes of air, like maybe 30% of a full inhale), excess gut bacteria causing d lactic acid production indicated as i get white coating on tongue in the morning. for this ive been taking bicarb, inhaling more full volume of air slowly, around 5 secs inhale, carrot salad slowly kill off to avoid herxheimer reaction. planning to take mct, antibiotics like doxycicline soon however and then repopulate with kefir, probiotic after i look more into which bacteria is beneficial like boullardi, lactobacillus. i think small intestine should be sterile and then large gut have some bacteria but not too much, think losing bacteria could cause lactose intolerance, digestion problems maybe. i then take promethazine, ondansetron every now and then but not too often to create tolerance, maybe cannabis oil soon. also found avoiding empty stomach in morning, atleast eating a bit helpful. when i was younger tho i could do intense exercise in morning while intermittent fasting not eating much later without issue, if id do that now id get nauseous

yerrag

@the-MOUSE

Mike Fave gives you his take on the gut:

https://www.youtube.com/watch?v=Bkph9FRpcAk&t=718s

Mike was a regular at RPF. He had been having gut issues, and struggled with it. He learned a lot in overcoming his gut issues. I never had real gut issues. It's always been good and became even better for me, learning from Ray Peat. So I cannot advise people on their gut issues just as people born with a silver spoon can't teach us how to make money. But Mike understands Ray Peat very well, and builds on it further. If you could get some coaching from him, it may do you a lot of good.

the MOUSE

@yerrag very good video and channel, definitely gonna look more into this guy, thank you.

@the-MOUSE
https://bioenergetic.forum/topic/1630/soil-health-and-its-relations-to-plant-animal-and-consequently-human-health/10

Have a look at the second post for ideas about gut health too. Not exactly the same type of approach but can still work.