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Experiments with transdermal hormones

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testosterone transdermal trt hormones
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  • S
    Santosh @Mulloch94
    last edited by May 3, 2024, 9:52 AM

    @Mulloch94 said in Experiments with transdermal hormones:

    @metabolicmilk What would be the purpose for trying something like Tren in the first place? It's a pretty destructive substance that has essentially no health benefits to it. The only people who need to consider Tren are people trying to get as big as possible, and even most of them know you're playing with fire when you take that shit. I mean, it's your body. I don't care if people smoke crystal meth, I'm just genuinely curious how we go from "fixing the metabolism" to trenbolognia sandwiches.

    Read my post above.
    Stop thinking you may know anything about a hormone in particular just because you read forums.

    M 1 Reply Last reply May 4, 2024, 2:47 AM Reply Quote 0
    • M
      Mulloch94 @Santosh
      last edited by May 4, 2024, 2:47 AM

      @Santosh Do you not think all the accounts people have of themselves (or family members) going crazy and literally threatening to harm themselves or others when taking tren isn't proof enough of it's toxic effects?

      S 1 Reply Last reply May 4, 2024, 2:43 PM Reply Quote 0
      • S
        Santosh @Mulloch94
        last edited by May 4, 2024, 2:43 PM

        @Mulloch94 said in Experiments with transdermal hormones:

        @Santosh Do you not think all the accounts people have of themselves (or family members) going crazy and literally threatening to harm themselves or others when taking tren isn't proof enough of it's toxic effects?

        You know these people personnally ?
        Anybody can write anything on the internet, including me.
        That's why you need to try these things for yourself.

        M 1 Reply Last reply May 4, 2024, 8:08 PM Reply Quote 0
        • M
          Mulloch94 @Santosh
          last edited by May 4, 2024, 8:08 PM

          @Santosh What's the significance of knowing them personally? Last time I checked there isn't some grand conspiracy against trenbolone. It's a substance that serves a particular purpose, and like anything, can have adverse reactions. Also 3 two week cycles isn't that much. I'm sure most people can get away with that before it becomes a huge issue. The typical tren cycle is like 10-12 weeks.

          Also you're acting like the only knock on tren thus far is personal anecdotes on forums. We know from research it can elevate prolactin and downregulate serotonin autoreceptors (which isn't good). This supports some of the notable cardio effects users talk about on those forums, like tachycardia and, in extreme cases, heart failure.

          S 1 Reply Last reply May 4, 2024, 11:47 PM Reply Quote 0
          • S
            Santosh @Mulloch94
            last edited by May 4, 2024, 11:47 PM

            @Mulloch94 said in Experiments with transdermal hormones:

            @Santosh What's the significance of knowing them personally? Last time I checked there isn't some grand conspiracy against trenbolone. It's a substance that serves a particular purpose, and like anything, can have adverse reactions. Also 3 two week cycles isn't that much. I'm sure most people can get away with that before it becomes a huge issue. The typical tren cycle is like 10-12 weeks.

            Also you're acting like the only knock on tren thus far is personal anecdotes on forums. We know from research it can elevate prolactin and downregulate serotonin autoreceptors (which isn't good). This supports some of the notable cardio effects users talk about on those forums, like tachycardia and, in extreme cases, heart failure.

            1. Completely reversing anhedonia only took 3x2 weeks.

            2. You agree that this length of time is not enough to give any harmful effect.

            3. Why do you keep preaching the harmfulness of these drugs then ?

            C 1 Reply Last reply May 5, 2024, 12:32 AM Reply Quote 0
            • C
              Crypt Keeper @Santosh
              last edited by May 5, 2024, 12:32 AM

              @Santosh What is the mechanism of tren fixing anhedonia? I might have to give this a try, although I think mine might be more related to low E2.

              S 1 Reply Last reply May 5, 2024, 9:43 AM Reply Quote 0
              • S
                Santosh @Crypt Keeper
                last edited by May 5, 2024, 9:43 AM

                @Crypt-Keeper said in Experiments with transdermal hormones:

                @Santosh What is the mechanism of tren fixing anhedonia? I might have to give this a try, although I think mine might be more related to low E2.

                Strong androgen receptor agonism that finally wakes up the dormant receptors that haven't been used at all your whole life.

                Look at how you and your generation looks like : soft cheeks, soft skin, frail looking without much muscle, thin neck, no energy.

                Look at how men who were born in the 50s look like : thick leathery oily skin with strong beards, thick necks, broad shoulders, natural muscle mass without working out, very strong will and never back down when a fight comes up.

                That means your receptors haven't worked much since the day you were born because of EDCs, the medications your mother took when she was pregnant, the soft way of life with computers you live.

                M 1 Reply Last reply May 17, 2024, 11:35 AM Reply Quote 0
                • B
                  brightside @Santosh
                  last edited by brightside May 6, 2024, 10:24 PM May 6, 2024, 10:21 PM

                  @Santosh said in Experiments with transdermal hormones:

                  What specific points make you think I do ?

                  Elaborate, don't just throw sarcastic questions especially while hypocritically prefacing they are genuine.

                  Why would I elaborate when you won't read it anyways? That's the point.

                  I'm not hypocritical, though. If you answer genuinely, I will too. Not everyone's like you

                  S 1 Reply Last reply May 7, 2024, 6:06 AM Reply Quote 0
                  • S
                    Santosh @brightside
                    last edited by Santosh May 7, 2024, 6:06 AM May 7, 2024, 6:06 AM

                    @brightside said in Experiments with transdermal hormones:

                    @Santosh said in Experiments with transdermal hormones:

                    What specific points make you think I do ?

                    Elaborate, don't just throw sarcastic questions especially while hypocritically prefacing they are genuine.

                    Why would I elaborate when you won't read it anyways? That's the point.

                    I'm not hypocritical, though. If you answer genuinely, I will too. Not everyone's like you

                    Prefacing a question with the word "genuinely" while making this question rethorical and sarcastic is, indeed, hypocritical.

                    1 Reply Last reply Reply Quote 0
                    • M
                      metabolicmilk @Santosh
                      last edited by May 17, 2024, 11:35 AM

                      @Santosh This is interesting. Thanks for sharing your experience! Do you mind sharing your protocol/dosing? Also why only 2 weeks and how long inbetween did you wait before starting your next 2 weeks?

                      1 Reply Last reply Reply Quote 0
                      • C
                        Crypt Keeper
                        last edited by May 30, 2024, 12:22 AM

                        Where are people getting 96% ethanol? Is this another thing that's impossible to get in the US because it has stupid laws?

                        Also, is there a concern about soap residue on the skin being absorbed by DMSO application?

                        ? 1 Reply Last reply May 30, 2024, 12:52 AM Reply Quote 0
                        • ?
                          A Former User @Crypt Keeper
                          last edited by May 30, 2024, 12:52 AM

                          @Crypt-Keeper
                          it's available in alberta canada

                          1 Reply Last reply Reply Quote 0
                          • R
                            risingfire @thyroidchor27
                            last edited by May 31, 2024, 12:50 PM

                            @thyroidchor27 Ray say the average healthy male produces around 7mgs a day of testosterone. To be safe, 7mgs shouldn't shut down the gonadal axis.

                            1 Reply Last reply Reply Quote 0
                            • C
                              Crypt Keeper
                              last edited by Jun 4, 2024, 5:59 PM

                              I finally got around to trying T in DMSO. Maybe 100 mg T per 1 ml DMSO was too concentrated because there were some crystals left over after application. No white residue or powder, but definitely some kind of tiny glitter on my skin that was only visible in bright light.

                              I tried 25mg, 100mg and 200mg applications and felt absolutely nothing different. Absolutely nothing. Like as if I smeared water on my skin (other than the DMSO burn).

                              This is about what I expected though. Some would be tempted to say that my powder is bunk, and maybe it is. But it confirms my suspicion that those who "feel" something from these hormones are either working with placebo, or have low testosterone to begin with. Mood, energy, strength -- nothing. Probably once you're in the high-normal range for T, blasting into the stratosphere doesn't do much more for you.

                              I think I will run this bottle out with 5-15mg applications once or twice a day just to help keep T in the upper range.

                              DMSO is awful to work with. Completely impractical for a regular basis. I'll try the (95%) ethanol formulas next.

                              It would be good if there was a way to pre-treat the skin with some kind of 5-ar inhibitor like topical finasteride to prevent DHT conversion. But then DMSO would bring that in and make it systemic, which you wouldn't want.

                              Overall I would say that I'm completely unimpressed. But microdosing T with a non-DMSO formula over the long haul might be helpful for gym purposes at least.

                              S 1 Reply Last reply Jun 5, 2024, 1:19 PM Reply Quote 0
                              • S
                                Santosh @Crypt Keeper
                                last edited by Jun 5, 2024, 1:19 PM

                                @Crypt-Keeper said in Experiments with transdermal hormones:

                                I finally got around to trying T in DMSO. Maybe 100 mg T per 1 ml DMSO was too concentrated because there were some crystals left over after application. No white residue or powder, but definitely some kind of tiny glitter on my skin that was only visible in bright light.

                                I tried 25mg, 100mg and 200mg applications and felt absolutely nothing different. Absolutely nothing. Like as if I smeared water on my skin (other than the DMSO burn).

                                This is about what I expected though. Some would be tempted to say that my powder is bunk, and maybe it is. But it confirms my suspicion that those who "feel" something from these hormones are either working with placebo, or have low testosterone to begin with. Mood, energy, strength -- nothing. Probably once you're in the high-normal range for T, blasting into the stratosphere doesn't do much more for you.

                                I think I will run this bottle out with 5-15mg applications once or twice a day just to help keep T in the upper range.

                                DMSO is awful to work with. Completely impractical for a regular basis. I'll try the (95%) ethanol formulas next.

                                It would be good if there was a way to pre-treat the skin with some kind of 5-ar inhibitor like topical finasteride to prevent DHT conversion. But then DMSO would bring that in and make it systemic, which you wouldn't want.

                                Overall I would say that I'm completely unimpressed. But microdosing T with a non-DMSO formula over the long haul might be helpful for gym purposes at least.

                                Your powder is bunk, indeed.
                                There is nothing placebo about the testosterone base surge you feel in DMSO, especially when you use 100mg or more at a time.

                                Those who have tried it know.
                                Those who wish they tried it scream placebo.

                                C 1 Reply Last reply Jun 5, 2024, 1:44 PM Reply Quote 0
                                • C
                                  Crypt Keeper @Santosh
                                  last edited by Jun 5, 2024, 1:44 PM

                                  @Santosh said in Experiments with transdermal hormones:

                                  Your powder is bunk, indeed.

                                  I guess I will send it off to Janoshik since it's probably important to know what I'm taking into my body with DMSO.

                                  I found it strange that PPL had a message on their website saying not to test with Janoshik and anyone who posted results from them on a forum would be banned from buying again.

                                  Guess I'll look elsewhere for raws.

                                  M S 2 Replies Last reply Jun 5, 2024, 2:34 PM Reply Quote 0
                                  • M
                                    Mallard6146 @Crypt Keeper
                                    last edited by Jun 5, 2024, 2:34 PM

                                    @Crypt-Keeper

                                    Qingdao Sigma Chemical Co seems to get good reviews on other forums. I’m going to try an order of base with them soon. Same formula with DMSO. First time I’ve used any exogenous test. We’ll see how it goes.

                                    C 1 Reply Last reply Jun 5, 2024, 2:38 PM Reply Quote 0
                                    • C
                                      Crypt Keeper @Mallard6146
                                      last edited by Jun 5, 2024, 2:38 PM

                                      @Mallard6146 said in Experiments with transdermal hormones:

                                      @Crypt-Keeper

                                      Qingdao Sigma Chemical Co seems to get good reviews on other forums. I’m going to try an order of base with them soon. Same formula with DMSO. First time I’ve used any exogenous test. We’ll see how it goes.

                                      Let us know your experience. I'm getting cold feet on the legal aspect of some of this stuff (paranoia) but would love to continue experimenting nevertheless since I find all of this so interesting.

                                      P 1 Reply Last reply Jun 5, 2024, 4:34 PM Reply Quote 0
                                      • P
                                        pannacottas @Crypt Keeper
                                        last edited by Jun 5, 2024, 4:34 PM

                                        @Crypt-Keeper I've ordered dht base from QSC and had it tested at Janoshik, came back with 98%+ purity. Imo they are legit and they have better prices that PPL anyways.

                                        C 1 Reply Last reply Jun 5, 2024, 4:43 PM Reply Quote 0
                                        • C
                                          Crypt Keeper @pannacottas
                                          last edited by Jun 5, 2024, 4:43 PM

                                          @pannacottas said in Experiments with transdermal hormones:

                                          @Crypt-Keeper I've ordered dht base from QSC and had it tested at Janoshik, came back with 98%+ purity. Imo they are legit and they have better prices that PPL anyways.

                                          Thank you. Have you tried DHT in DMSO? Do you feel anything? I also have some DHT from PPL (same shipment) which has slightly different characteristics to the T base so I might try it in DMSO to see if at least that is legit.

                                          S P 2 Replies Last reply Jun 6, 2024, 6:44 AM Reply Quote 0
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