What's the worst endocrine disruptor?

insufferable

I've always wanted to quantify this, like

pre-1900's guys had 900 ng/dl testosterone
today they have 450 ng/dl

so we have a decline of 450 ng/dl to account for:
-200 ng/dl from prenatal damage from maternal pharma use
-150 from sleeping too little
-75 from pesticide dust in the air
-25 from pesticide in the food
-0.1 from not consuming enough vitamin 521

Obviously something bad is going on these days with a decline in thyroid function, hormone function, mental health, metabolism - but I want to be more specific so we know what to focus on first.

Will switching your polyester shorts for the twitter shorts (100% cotton!) be the most important thing for restoring perfect HUNTER GATHERER health? Will EMF mitigation fix everything, or should you have first put that focus into something else that helps more?

I imagine the biggest impacts are:

pharma (especially prenatal)
personal care products (especially prenatal)
deep fried sneed oils (im not convinced unheated pufa is bad. Fake peater alert)
emulsifiers
TV, computers, smartphones - both psychologically and also because of the artificial light emitted

While Red 40 food coloring, plastic water bottles, and escaping all wifi are probably lower priority.

It's a question of what would you recommend to a tired person down in the vicious cycle of bad health? Remove the SSRI or remove all the food in the pantry cause it has food coloring in it? Surely you start with the SSRI. The food coloring comes later.

What do you think?

insufferable

My understanding is that the primary route of MICROPLASTICS exposure is household dust from synthetic fabrics in your house getting dustified over time.

So the main reason there's microplastics in your blood is

your polyester carpets,
your polyester fabric couch,
and your polyester fabric pants getting abraded in the washer.

So I imagine the quickest impact you can make on microplastic exposure is to remove dust frequently, and to get a 100% cotton couch cover. Biggest impact would be to replace the polyester carpet. Then replace polyester clothes with cotton, etc.

But much less impactful would be a heavy focus on microplastic content of food from the grocery store. That's because this isn't the main route of microplastic exposure.

I'd like to determine this sort of thing for all the endocrine disruptors! For example, which is more important: pesticide in food, pesticide in water, or airborne environmental pesticide entering your household dust?

insufferable

I think the pesticide Atrazine specifically is probably a huge offender. The Midwest (full of huge cornfields) went from the highest testosterone in the US in 1990 to the lowest, currently. Atrazine is known to be a super potent endocrine disruptor, and it's used widely on cornfields. (and others?)

I think atrazine is responsible for a 250 ng/dl testosterone drop.

What about glyphosate? I'm not sure but I bet it's less impactful.

What are the main routes of atrazine exposure? Living next to a cornfield, having a water source that goes through atrazine country, or eating non-organic corn products? I believe the first two are probably worse than the last. During the time of year that they spray it, in corn farming parts of the midwest. Atrazine enters water and spikes to levels well above the max.

DavidPS

Atrazine is definitely a major endocrine disruptor.

Chronic Exposure to the Herbicide, Atrazine, Causes Mitochondrial Dysfunction and Insulin Resistance
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0005186