B1 Thiamine injections

[bigpeeter]

my local naturopath offers vit B injections, these are the ingredients

1 cc of Methylcobalamin, 0.5 cc of 5-MTHF, and 0.5 cc of Vitamin B1.

What would be the equivalent oral dose of this B1 injection? I took one and considering taking more.

Unsure about the 5-MTHF ?

thanks

[CrumblingCookie]

@bigpeeter

The above listing does not tell anything about the concentration / content of the vitamins.

Commonly, vitamin B1 hydrochloride is being offered at 50mg/mL and rarely at 100mg/mL solutions.
For your 0.5mL I would therefore assume that it was 25-50mg of thiamin-HCl.
To compare it's fair to multiply the injected amount by 70-140 for an equivalent oral weekly dose. That's Antonio Costantini's guideline and checks out (100mg injection 1x/2x weekly -> ~ 2g oral thiamin daily). These 25-50mg therefore correspond to about 500mg of B1 per day.

No clues are given to how much 5-MTHF is in that 0.5mL.
1mL of methy-B12 has usually 500-1000mcg.

[bigpeeter]

@CrumblingCookie

Thanks for your explanation! I was able to get a prescription for B1 only injections but this time I was prescribed 200mg per week, so that sounds like quite a large dose according to what your saying.

"Antonio Costantini's guideline and checks out (100mg injection 1x/2x weekly -> ~ 2g oral thiamin daily)."

Not knowing that I was going to get these injections I also order a bag of powdered B1 and Benfotiamine so I now have a pretty good supply in my hands to see what this will do for me.

[BioEclectic]

I am not suggesting the following to the original poster since everyone's goals and medical needs are different, and what works for some may not work for all.

Some folks who had sought a substitute for thiamine injections turned to 100mg of sublingual thiamine mononitrate. What maladies they were treating i do not recall. Most of them were using Superior Source No Shot B1 100mg MicroLingual tablets.

Edit: i managed to dig up one of the discussions i had read, turns out it was for Parkinsons sufferers: https://healthunlocked.com/cure-parkinsons/posts/146847819/how-to-take-sublingual-b1

The original poster in that discussion was even able to divide her sublingual dose in half and still feel it's effects. It may also be a decent experiment for those looking to avoid B1 spikes and dips by doing a half dose twice a day, then monitoring the quality of it's effect afterward.

[CrumblingCookie]

@bigpeeter
Good stuff. Do report how you feel from it.
IMO you should feel immediate positive effects - unless you belong to the kind of people who can have a brick fall onto their heads and only weeks later vaguely complain about their getting older and an oddly stiff neck.
Remember to provide enough cofactors (no high dosing, simply a sufficient baseline) to this B1.