Methionine/Cysteine restriction increases longetivity AND energy expenditure
-
@Mauritio - This is continues to be a great thread. In the link below, Dr. Peat explains what Broda Barnes discovered when he doubled his protein intake.
Dr Ray Peat - Blood Tests, Hormones, Protein Intake, & Ray's Carb List
-
@evan-hinkle said in Methionine/Cysteine restriction increases longetivity AND energy expenditure:
@Ecstatic_Hamster are you experimenting with it? If so how long, and any noticeable effects?
No not right now. I am moving more to lower protein and more plant options.
-
Instead of looking for hacks to mitigate the negative effects of methionine just stop eating it. Its like complaining you can't lose weight while stuffing yourself with fast food every day. This guy is catching on but not quite there yet:
@DavidPS said in Methionine/Cysteine restriction increases longetivity AND energy expenditure:
As you can see, the greatest source of methionine comes from foods of animal origin, especially chicken and fish. I am unwilling to adopt a diet based solely on plant foods and I use glycine to balance the methionine in my diet (after I have reduced it to an level that I still find appetizing).
Just follow Kempner's rice diet if you don't know where to begin. Eating only plants won't make you gay. Anyone experiencing insatiable hunger on high C, low P/F, might just not be eating enough. See posts from Kelj on old RPF. The more carbs you eat the higher you can push and restore metabolism.
I was at around 6k+ calories for a few weeks before it slowly dropped off. Eat to appetite even if that means 6k cal. When the food stops tasting good and you want to push the plate away, that's when your body has had enough. Something like 1400g carbs, 100g protein. Lots of table sugar, like in Kempner's where they added up to 500g of it. Even substituted some rice for mung bean starch since the protein in rice becomes unpalatable after eating a couple stacked plates of it.
Eating around 4000 now but I don't really track. Protein usually ends up under 70g. Mostly just fruit, tubers, leaves, rice, sugar. There was some vegan peating discussion on old RPF. Westside PUFAs had a thread, others I can't recall off the top of my head. Cirion had an interesting thread on self-experimenting with Protein/AA restriction.
-
@DavidPS That audio clip speaks directly to this thread.
In it, Peat mentions:
(i) Broda Barnes' finding that doubling dietary protein doubled his exogenous NDT requirement;
(ii) after the age of 30, aminio acids "of replacement" (especially methionine and cysteine) become inflammatory (at least in excess), and restricting them can be especially helpful for people that don't respond well to thyroid supplementation and/or have paradoxical inflammatory symptoms;
(iii) Peat recommends a 1:7 ratio of protein to carbohydrate or, equivalently (with some other assumptions about macros), 80-100g of protein in a 4000 calorie diet for a 30-year old man should be adjusted downward to 40-50g of protein in a 2000 calorie diet for an 80-year old;
(iv) limiting M-TOR with dietary methionine restriction (or taking rapamycin, as advocated by Tarmander at RPF) are worth considering as life-extension strategies based on the rodent studies @Mauritio posted in this thread.Thanks for so consistently focusing us and directing attention to what's germane and highly relevant!
-
This post is deleted!