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    Mice fed a 0% protein diet for a week lost nearly 20% of their body mass

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    • JenniferJ
      Jennifer @serotoninskeptic
      last edited by Jennifer

      @Sugarnotsnow, you’re welcome. 🙂 Part of me questions if his opinion changed because he experienced benefits from reducing his protein intake the last year of his life. He said that it gave him energy, he was able to reduce his thyroid dose and his remaining allergies went away. However, he ended up having that nasty allergic reaction to veggies that affected his throat for months before his passing, and he had previously said that allergies are due to low thyroid function so did lowering his protein intake improve his thyroid function or actually worsen it as the experiment progressed?

      From my understanding, Ray’s low protein experiment lasted less than a year before he passed away so we’ll never know how he would have fared on it long-term. I only know how I fared on it so I can’t say with confidence that 45–50 g would be sufficient. I’ve been eating fruit-based since March of this year and as my protein intake decreased, my TSH increased. My most recent labs were done yesterday and it looks like my doctor will be putting me back on thyroid. I can’t say for certain my protein intake is the cause. All I know is, my prior diet was dairy-based and I averaged far more protein than I do now.

      I have stood on a mountain of no’s for one yes. ~ B. Smith

      serotoninskepticS ? 2 Replies Last reply Reply Quote 0
      • serotoninskepticS
        serotoninskeptic @Jennifer
        last edited by serotoninskeptic

        @Jennifer Hm thank you for sharing your experience. As you know from our conversations I also did not fare well on a low-protein fruitarian diet. However I feel like its unfair to blame it all on protein in my case. The diet was deficient in so many nutrients including fat solubles, zinc, selenium, B vitamins etc. I was able to completely reverse most the damage i did on that diet by eating lots of full fat dairy. Milk, cheese, and ice cream made up the majority of what i ate. I did put on some weight in this process but I was very underweight before then (105 lbs at my lowest) as a 5"10 adult male. Now im experimenting again with lower protein intake (55-60g) by replacing the milk/cheese with cream and having one protein based meal a day featuring yogurt and eggs. I feel good so far and have noticed no negative effects. My temps and pulse are quite stable as well. How are your temps now that you are trying lower protein?

        JenniferJ 1 Reply Last reply Reply Quote 0
        • JenniferJ
          Jennifer @serotoninskeptic
          last edited by Jennifer

          @Sugarnotsnow, oh my. 105 at 5’10”? I’m so glad you changed course when you did. I can’t remember if you mentioned your caloric intake while on the fruitarian diet? I consumed so many calories that the only nutrients my diet was low in were protein and vitamin D. I sunbathed for D, but I still ended up deficient. My midday temp is lower now, but it’s still normal—98.6° fruit-based vs 99° dairy-based—however, my pulse dropped significantly—from an average of 85 while dairy-based to as low as 50 while fruit-based. It’s currently holding at 70. It wasn’t a conscious decision on my part to lower my protein intake. I lost my appetite a little over 2 months ago and the easiest things for me to get down have been nice cream and juice, but I’ve been forcing myself to have a meal of eggs in the evening just so that I get some animal protein and salt.

          I have stood on a mountain of no’s for one yes. ~ B. Smith

          serotoninskepticS 1 Reply Last reply Reply Quote 0
          • serotoninskepticS
            serotoninskeptic @Jennifer
            last edited by

            @Jennifer At first transitioning to fruitarian I was likely eating 2k calories or less which is how I lost so much weight. Towards the end of my vegan run however I attempted to see if I could gain weight back while remaining fruitarian. I was eating upwards of 10k calories of mostly fruit juice and still couldn't gain much weight. You can probably imagine how difficult it is to get that much calories of fruit alone. I feel like this is sort of proof that CICO isn't as simple as they make it seem. Maybe your loss in appetite was a sign that your thyroid health was already beginning to suffer? I know when I was at my lowest health and energy wise I also had very little appetite

            JenniferJ 1 Reply Last reply Reply Quote 0
            • JenniferJ
              Jennifer @serotoninskeptic
              last edited by Jennifer

              @Sugarnotsnow, 10k calories of mostly juice must have been really expensive, huh? But yep, CICO isn’t as simple as they make it seem. Thyroid function alone will determine the rate of evaporation/metabolic rate. I do think my loss of appetite was a sign that my thyroid was beginning to suffer, since it happens every time.

              I have stood on a mountain of no’s for one yes. ~ B. Smith

              serotoninskepticS 1 Reply Last reply Reply Quote 0
              • serotoninskepticS
                serotoninskeptic @Jennifer
                last edited by

                @Jennifer Yea and a LOT of juicing 😅 I couldnt tolerate store bought juice so i was juicing multiple lbs of oranges, grapes, and melons every day just to get enough

                JenniferJ 1 Reply Last reply Reply Quote 0
                • JenniferJ
                  Jennifer @serotoninskeptic
                  last edited by Jennifer

                  @Sugarnotsnow, yeah that! For my SIBO elimination diet, I juiced 14 lb of honeydew flesh daily with a Vitamix. I used a coffee filter to remove as much fiber as possible because it fed the overgrowth so it took me over 2 hours to juice. That was an expensive diet. For one day’s worth, the melon cost $30, a pound of scallops and crab cost $25, and along with a few miscellaneous foods like coconut oil, I was spending $400 a week on groceries.

                  I have stood on a mountain of no’s for one yes. ~ B. Smith

                  serotoninskepticS 1 Reply Last reply Reply Quote 0
                  • serotoninskepticS
                    serotoninskeptic @Jennifer
                    last edited by

                    @Jennifer Haha i can totally relate. I never had to manually filter the juice. But the juicing and peeling process itself took upwards of 2 hours as well. And two of my juicers broke from actively using them at hours on end every single day lol

                    JenniferJ 1 Reply Last reply Reply Quote 0
                    • JenniferJ
                      Jennifer @serotoninskeptic
                      last edited by

                      @Sugarnotsnow, if only we had the Nama J2 back then.

                      I have stood on a mountain of no’s for one yes. ~ B. Smith

                      serotoninskepticS 1 Reply Last reply Reply Quote 0
                      • ?
                        A Former User @Jennifer
                        last edited by

                        @Jennifer

                        Well considering he died…. I do think we know how he would fare on a low protein diet lol.

                        serotoninskepticS JenniferJ 2 Replies Last reply Reply Quote 0
                        • TexugoDoMelT
                          TexugoDoMel
                          last edited by

                          There are some studies saying that uncoupling protects the muscles, so I imagine it's something related. I think it's common knowledge that DNP seems to preserve a lot of muscle mass even if you lose a lot of weight (compared to fat loss with ozempic for example). When protein is restricted there is an increase in T3, uncoupling, brown fat... So this could be one of the reasons, but I don't know if it would preserve it for long

                          Low protein has twice as much t3
                          dd70dc2a-2aed-4f65-ad71-04f1da2a4e0c-image.png

                          6dd996b7-27f0-447c-a547-ec55ccf322f3-image.png
                          15d6a64b-3f00-4c29-a760-3565dbe87038-image.png

                          serotoninskepticS 1 Reply Last reply Reply Quote 0
                          • serotoninskepticS
                            serotoninskeptic @TexugoDoMel
                            last edited by

                            @TexugoDoMel Sugar also has a muscle and protein preserving effect. So if one were fed a high carb-low protein diet this could be a protective factor.

                            1 Reply Last reply Reply Quote 0
                            • serotoninskepticS
                              serotoninskeptic @Jennifer
                              last edited by

                              @Jennifer I still dont have one 😢

                              JenniferJ 1 Reply Last reply Reply Quote 0
                              • serotoninskepticS
                                serotoninskeptic @A Former User
                                last edited by

                                @RawGoatMilk88 I doubt the low-protein experiment caused his death. If anything it couldve been an attempt to cure whatever health condition he was already dealing with which lead to his death.

                                ? 1 Reply Last reply Reply Quote 0
                                • ?
                                  A Former User @serotoninskeptic
                                  last edited by

                                  @Serotoninskeptic

                                  Certainly didn’t help.

                                  serotoninskepticS 1 Reply Last reply Reply Quote 0
                                  • serotoninskepticS
                                    serotoninskeptic @A Former User
                                    last edited by

                                    @RawGoatMilk88 Yeah but if he was still young and healthy and didnt have an underlying condition he may have fared well, if not possibly better than a higher protein diet. I think thats what Jennifer was getting at atleast.

                                    1 Reply Last reply Reply Quote 0
                                    • JenniferJ
                                      Jennifer @A Former User
                                      last edited by Jennifer

                                      @RawGoatMilk88 said in Mice fed a 0% protein diet for a week lost nearly 20% of their body mass:

                                      @Jennifer

                                      Well considering he died…. I do think we know how he would fare on a low protein diet lol.

                                      What Serotoninskeptic said. For all I know, Ray was motivated to experiment with low methionine because his health was failing and no intervention he tried was going to extend his life.

                                      I have stood on a mountain of no’s for one yes. ~ B. Smith

                                      1 Reply Last reply Reply Quote 0
                                      • JenniferJ
                                        Jennifer @serotoninskeptic
                                        last edited by

                                        @Serotoninskeptic said in Mice fed a 0% protein diet for a week lost nearly 20% of their body mass:

                                        @Jennifer I still dont have one 😢

                                        Neither do I. I was going to buy it, but I can’t see spending $550 on a juicer when I can get fresh-pressed cider for $8 a gallon. I did the math and it would cost me around $12 to juice a gallon’s worth of apples.

                                        I have stood on a mountain of no’s for one yes. ~ B. Smith

                                        serotoninskepticS 1 Reply Last reply Reply Quote 0
                                        • serotoninskepticS
                                          serotoninskeptic @Jennifer
                                          last edited by

                                          @Jennifer Yess im so glad fresh unpasteurized apple cider is back at my farmer's market 😃

                                          JenniferJ 1 Reply Last reply Reply Quote 0
                                          • JenniferJ
                                            Jennifer @serotoninskeptic
                                            last edited by

                                            @Serotoninskeptic, nice! The one I get is pasteurized, but it’s available year round and I like my cider heated up anyway with some cinnamon and vanilla bean. 🙂

                                            I have stood on a mountain of no’s for one yes. ~ B. Smith

                                            serotoninskepticS 1 Reply Last reply Reply Quote 0
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