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A bunch of random studies #1

Bioenergetics Discussion
coconut oil tendon nicotinamide depression sleep
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    cs3000
    last edited by cs3000 Nov 5, 2024, 3:00 PM Nov 5, 2024, 2:53 PM

    1. lauric acid (from coconut oil) + glucose reverses heart atrophy ( paradoxically lauric acid can cause heart atrophy at higher amounts >2% of diet because of overstimulation causing excess oxidative stress https://pmc.ncbi.nlm.nih.gov/articles/PMC6240279/,
      but ~25g coconut oil daily should be a good amount without oxidative stress, especially if split into meals

      https://onlinelibrary.wiley.com/doi/full/10.1111/cas.14656

    Combined administration of lauric acid and glucose improved cancer-derived cardiac atrophy in a mouse cachexia model

    c037c10c-16c1-4590-958c-145a27c337ed-image.png


    1. bromelain increases tendon healing at ~70mg - 100mg (increases tenocyte proliferation / maturation) https://www.liebertpub.com/doi/abs/10.1089/jmf.2010.0078

    1. in rare cases milk sugar (lactose->galactose) causes cataracts, maybe worth trying elimination to see if fixes https://www.sciencedirect.com/science/article/abs/pii/0002939452915870

    1. 100mg nicotinamide in humans acutely raises plasma serotonin >50% (and increases histamine) https://www.researchgate.net/publication/235682105_Excess_nicotinamide_increases_plasma_serotonin_and_histamine_levels

    bd938260-c00b-4d0f-b4d6-47aa632907e7-image.png

    There's an antimicrobial peptide in saliva that inhibits viruses / covid (LL37) - but nicotinamide/niacinamide is needed for the full effect https://pmc.ncbi.nlm.nih.gov/articles/PMC10663372/

    1c867d9c-903e-49d7-88e2-5988683d4de1-image.png 63af2475-7051-4e7e-870e-630358f01bd5-image.png


    1. saturating gauze with lactoferin closed wounds after bone necrosis surgery in 1-2 weeks
      instead of 2-3 months https://pubmed.ncbi.nlm.nih.gov/29435826/

    1. Brain restoration timeframe for previous meth users (maybe similar with a lot of porn time or maybe overstimulating multiplayer games for hours routinely) - in abstinence setting , takes 8 weeks to reset depression+anxiety scores from 13.1 to 4.8 , a 65% reduction by 2 months with 3 days a week information program https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560957/
      or get a 85% depression+anxiety reduction by the 2 months if exercise (or possibly heating body?) 3 days a week 45 mins (30 minutes cardio, 15 minutes weights) + 5 min stretch

    1. normalized REM sleep start = commonly 60+ minutes , in depression its common to see it hit at 0 minutes or <60
      https://core.ac.uk/reader/148255294?utm_source=linkout
      https://pubmed.ncbi.nlm.nih.gov/183839/7

    70e93196-af51-42ca-8faa-12981a3e4fc8-image.png


    "world," as a source of new perceptions
    more https://substack.com/@cs3001

    "Self-organizing systems decay only if they have assimilated inertia and — with a little support of the right kind— the centers of degeneration can become centers of regeneration"

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