Random, interesting studies
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Aronia berry
A small amount of the extract increased the body temperature of women by over a degree.
https://pmc.ncbi.nlm.nih.gov/articles/PMC3843504/#Sec2Anthocyanins from Aronia (cyanidin
291 3-arabinoside, cyanidin 3-galactoside, cyanidin 3-xyloside and cyanidin 3-glucoside) increased the effects of the anti aging protein klotho.
It increased several health markers of the brain.
They also increased antioxidants and monoanines of which dopamine was increased the strongest in the brain.
They also drastically down regulated COX-2 and inflammatory cytokines.
https://pubmed.ncbi.nlm.nih.gov/28657734/Aronia polyphenols drastically increased PGC1a in Brown adipose tissue (new mitochondria) and slightly increased UCP1.
https://pmc.ncbi.nlm.nih.gov/articles/PMC7339576Here we got an anti-inflammatory effect of aronia. But what's more interesting is that they used histamine and serotonin to induce the inflammation, including the (paw) edema. Notably, the concentration needed to induce inflammation was 50 times lower for serotonin than for histmine. And histamine is a known inflammation induced, yet you rarely hear the same thing about serotonin, although it seems to be a lot more harmful in that regard.
"Inflammation of rat hind paw was induced either by 0.5% solution of histamine or by 0.01% solution of serotonin."
https://pubmed.ncbi.nlm.nih.gov/7892768/Dare to think.
My X:
x.com/Metabolicmonstr -
Dopamine and noradrenaline drastically reduced in part of the brain. Serotonin not.
In PD, the levels of dopamine and noradrenaline were greatly reduced by 93 and 81%, respectively.
https://pubmed.ncbi.nlm.nih.gov/27741357/ -
Cacao polyphenols have anti-viral effects
https://www.sciencedirect.com/science/article/pii/S2405844023030670
https://pmc.ncbi.nlm.nih.gov/articles/PMC8141698/ -
@Mauritio Aronia products are being pushed by marketers so much lol
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2.0 g of meldonium daily for 90 days improved sperm health increased testosterone by about 70% in boars.
https://www.wellesu.com/10.1016/j.anireprosci.2012.11.007
"Meldonium treatment in both models restored mitochondrial bioenergetics. The results show that meldonium treatment prevents the development of RV and LV systolic dysfunction by enhancing mitochondrial function in experimental models of ventricular dysfunction that resembles cardiovascular complications in COVID-19 patients."
https://pmc.ncbi.nlm.nih.gov/articles/PMC8744985/Reducing FAO Enhances Antiviral Signals
https://pubmed.ncbi.nlm.nih.gov/39142373/ -
@Mauritio Wow nice, Ive been taking mildronate for close to 3 months now. Love it so far, great energy and a sort of calmness. Been loosing weight too.
these soviet medicines I sure do like
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@Mauritio What bible do you consume? My suggestion is to read the original text and not some sorry ass translation.
The soul is the metabolism, the spirit is the mind.
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@heyman how much are you taking?
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@Mauritio 0,5g to 1g a day
really like it, I get this calm, nice energy from it.
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@heyman interesting. I've been taking it for two days . First became really hypoglycemic .
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Pregnenolone reduces cocaine consumption in addicts.
Dosage: 300 or 500mg per day.Also interesting that 300mg increased plasma pregnenolone levels more than 500mg after a few weeks.
https://www.medrxiv.org/content/10.1101/2025.01.07.25320141v1.full
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Aspirin for autism?
In this animal model aspirin worked as a treatment for autism.
It completely restored their sociability and improved cognition and oxidative stress.
The human equivalent dosage was around 600mg.
https://pubmed.ncbi.nlm.nih.gov/40918592/ -
They accidentally gave 2 million IUs of vitamin D to a 90 and a 95 year old.
Interestingly, except for a transient spike of Vitamin D levels above the reference range, they were fine. -
DHEA seems to have some interesting antiviral effects.
At least partly because of its ability to protect the thymus gland from Glucocorticoids.
Sources:pubmed.ncbi.nlm.nih.gov/20407244/
pubmed.ncbi.nlm.nih.gov/1835439/
pubmed.ncbi.nlm.nih.gov/18682333/
pubmed.ncbi.nlm.nih.gov/2141095/
pubmed.ncbi.nlm.nih.gov/18462821/
pubmed.ncbi.nlm.nih.gov/2974468/
pubmed.ncbi.nlm.nih.gov/20202657/ -
Just wanted to add my thanks to @Mauritio for continuing to add to this fascinating collection of studies.
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@rpc thanks!
I posted them on twitter during the last weeks. But it seems to me that there is less overlap between the audience on here and twitter, than I thought. So I'll try to post them on both platforms in the future.Dare to think.
My X:
x.com/Metabolicmonstr -
@rpc said in Random, interesting studies:
Just wanted to add my thanks to @Mauritio for continuing to add to this fascinating collection of studies.
Ya, me too. Good job.
Even when there is no comment. At least you can see the random reading, I suppose. Has to be confirmed: => eye logo 29.8k -
@rpc he is great
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@Mauritio i dont go on twitters unless u post a nitter link as im too lazy to go on nitter for ur account myself
