FAO vs Beta Oxidation
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I have read many posts on various Peat sites about fatty acid oxidation/FAO and beta oxidation.
But I am not clear on these two processes.
Is FAO the burning of fatty acids OUTSIDE of the mitochondria, in the cytoplasm?
Is it not part of the Krebs cycle, or the electron transport chain?
What is produced in this? ATP?
Is FAO perfectly normal, when not excessive?
And is beta oxidation of fat OUTSIDE of the mitochondria, in the cytoplasm?
What is produced in this? ATP?
Is it not part of the Krebs cycle, or the electron transport chain?
Is this much less efficient than OXPHOS (I believe the burning of glucose in the mitos)?
Is beta oxidation perfectly normal, when not excessive? -
https://www.jayfeldmanwellness.com/carbs-vs-fats-which-is-the-better-fuel/
Jay’s article has been the most helpful for me to understand
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@AinmBeo Beta oxidation is fatty acid oxidation, and vice versa, i.e. they are the same thing.
This takes place inside the mitochondria, feeding acetyl-CoA into the Krebs cycle and then NADH/FADH to the electron transport chain.
It is normal, we are always burning some fatty acids and some glucose. I think issues arise when the glucose burning machinery is not working and the body has to rely excessively on fatty acid oxidation for its energy needs.
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@BroJonas
Thanks. This is really helpful.