PSSD since taking Olanzapine (an antipsychotic) - genital numbness (lack of pleasure in genitals), anhedonia etc.

Maximalus

Hello everyone.

Earlier this year I was given Olanzapine and took it for 2-3 months

Initially I went from 130lbs to 180lbs despite eating the same as before (before I could maintain 12% bodyfat around 17BMI and have visible abs/obliques and lean defined face no matter what I ate how much)

But that isn't the only issue

I also developed genital numbness - basically I can feel the touch itself but there is zero sense of pleasure during stimulation (in past I never had this issue at all) like a form of anesthesia

In most cases PSSD is from SSRIs but in my case I got it by antipsychotics

Also I have anhedonia (idk if it's the correct term) basically things don't feel as vivid anymore and subtle sensations e.g. when doing something or enjoying weather it feels more bland, there is less distinctiveness

I suspected my prolactin may be high, I tested it, but it was the SAME as before when I didn't have PSSD.

Has anyone had experience with PSSD or knows someone who has?

What could be the cause/-s and treatments?

ThinPicking

Hello Max. Are you under care/observation of a physician and have you described it to them? Please do that and follow up regularly.

Are you able to describe why you were given it to take, the context of that? Also the time since, I check results/recoveries/adjustments in myself in orders of three for no particular reason except patience. Three days, three weeks, three months. And can you let us know that you're eating well and a lot.

Maximalus

@ThinPicking

I haven't told my physician about the side effects yet

I got into a psych ward because someone online who knows my address threatened to come and stab me in real life, so I checked in there due to having a sort of breakdown+to hide there for a while

It's been more than 3 months since I stopped taking the antipsychotics but the symptoms persist, I stopped some time around march-april

I eat a quite Peaty diet - milk, various carbs (both starches and simple carbs), meat, coffee etc.

ThinPicking

@Maximalus said in PSSD since taking Olanzapine (an antipsychotic) - genital numbness (lack of pleasure in genitals), anhedonia etc.:

I eat a quite Peaty diet - milk, various carbs (both starches and simple carbs), meat, coffee etc.

Are you friendly with salt?

Maximalus

@ThinPicking I've always consumed salt in good amounts

The point is my diet was the same before developing PSSD as it is now and I haven't had any recovery yet due to what I eat

The only differentiation factor that gave me the symptoms is antipsychotic usage

ThinPicking

@Maximalus said in PSSD since taking Olanzapine (an antipsychotic) - genital numbness (lack of pleasure in genitals), anhedonia etc.:

The point is

There is a "differentiating factor" and you haven't thought to experimentally vary your dietary behaviour. Even your water consumption could have a bearing on something like this. You're more likely to find an answer experimentally than to get one. Carefully though, and you can document it here for feedback if it helps.

Apparently it's also been 3 months and you haven't discussed it with the clinician who gave it to you. Please go ahead and do that.