The anti-cortisol mechanism of trenbolone
-
It likely does turn into 16a hydroxytren because 17a tends to be in the gonads and adrenals whereas 16a hydroxylase is prominent in the liver and intestines
-
What is the safety profile of a tiny amount, say 3mg a day or 25mg a week? You still have that AR and PR agonism to deal with.
-
@engineer it’s been safe in animal models of less than 200mg a week.
No hospital case reports of anyone taking less than 100mg.
A guy took 25mg orally for a few weeks and got liver issues but I doubt he was intaking trenbolone, but another oral steroid. -
Tren implants increase testosterone and progesterone
https://pubmed.ncbi.nlm.nih.gov/573255/ -
@alfredoolivas ok, so if low dose tren can even increase T and P4, why are these bodybuilders using huge amounts and shutting themselves down?
-
Increases conversion of tryptophan into kynurenine pathway. Possibly reducing serotonin. Decreased catabolism too
http://pubmed.ncbi.nlm.nih.gov/40858/HED: 0.13mg/kg TBA a day.
-
Methyl Tren increases fertility of females.
https://pubmed.ncbi.nlm.nih.gov/528432/#:~:text=DOI%3A-,10.2527/jas1979.493729x,-No abstract available -
0.13mg/kg TBA a day was more effective than 2.5mg/kg TBA in supressing TAT.
-
"in France, the average weight for seniors tends to be around 66-67 kg"
For these people, 7mg a day of tren would supress TAT by 30%. This is what Parabolan would deliver shortly after the first injection
-
interdasting
-
@engineer bodybuilders are now starting to realise how powerful it is in low doses. Vigorous Steve was the one that put me onto this a year ago. It’s 8x more anabolic than testosterone, so of course they will abuse it and inject more.
-
Lowers prolactin and GH as well as insulin the most.
https://www.cambridge.org/core/journals/animal-science/article/abs/effect-of-trenbolone-on-acetate-growth-blood-hormones-and-metabolites-and-nitrogen-balance-of-beef-heifers/8B3677C602A7E26F05252173EBBD474C -
It decreases faty acid synthase, ACC in liver, adipose and muscle and LIPOLYSIS IN ADIPOSE TISSUE. It increases lipolysis in the liver and muscle, but allows adipose tissue to not release FFA into the blood!
10.1055/s-2007-1018919 -
Seems to make turkeys with weak legs more excitable, indicating it increases intracellular calcium
10.1080/00071688108447879
-
" the anabolic action of TP and TBA, especially in female rats, may be mediated through an antagonistic effect to the catabolic effects of oestrogens and glucocorticoids."
https://www.semanticscholar.org/paper/Effect-of-sex%2C-testosterone-propionate-and-acetate-Santidrián-Thompson/64ece3bf3a3cd424d83611cfad2d54f94912c41c -
decreases FFA " Plasma triglyceride concentrations in all
implanted groups fell markedly by week 5 and remained well
below control values until slaughter. The concentration of
plasma non-esterified fatty acids decreased by approximately
50% in all four treatment groups"
Low doses of tren & E2 had lower cholesterol.
-
"TB A also had no effect on either the digestibility or metabolizability of the energy in the diet, or on the total energy retained by the two experimental groups...there were significant differences in the way this energy was partitioned for growth between treated and control animals. "
It doesn't cause fat loss via increasing metabolism?
-
" Trenbolone, however, did not demonstrate any genotoxic effect in the assays performed."
https://pubmed.ncbi.nlm.nih.gov/3090982/ -
Decreases fat cell size
Decreases FAS and increases G6PD and other genes involved with NADPH formationhttps://pubmed.ncbi.nlm.nih.gov/3583947/
200mg TBA implant given once every 56 days with a 60 day withdrawal period.
I am not going to even estimate the amount of tren built up and released lol
But that is 3.57mg TBA (2.85mg elemental weight) every day given to Heifers, with a 60 day withdrawal period.
French were giving 5mg a day to 65kg humans XDXD.
Bro if 2.85mg of trenbolone can do this to a HEIFER after 60 days of no tren then imagine what 5mg does to a human @engineer -
I think tren only cycles may be good, because OVX with tren was often more effective than tren by itself.
Lowering endogenous sex steroids like progesterone, estradiol and test WITH tren can be even more anti-lipolitc.
