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    The anti-cortisol mechanism of trenbolone

    Scheduled Pinned Locked Moved Literature Review
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    • alfredoolivasA Offline
      alfredoolivas @engineer
      last edited by

      @engineer itโ€™s been safe in animal models of less than 200mg a week.
      No hospital case reports of anyone taking less than 100mg.
      A guy took 25mg orally for a few weeks and got liver issues but I doubt he was intaking trenbolone, but another oral steroid.

      1 Reply Last reply Reply Quote 1
      • alfredoolivasA Offline
        alfredoolivas
        last edited by

        Tren implants increase testosterone and progesterone
        d2b29223-3bdc-4953-9f8d-8ec86101c670-image.png
        https://pubmed.ncbi.nlm.nih.gov/573255/

        engineerE 1 Reply Last reply Reply Quote 0
        • engineerE Offline
          engineer @alfredoolivas
          last edited by

          @alfredoolivas ok, so if low dose tren can even increase T and P4, why are these bodybuilders using huge amounts and shutting themselves down?

          alfredoolivasA 1 Reply Last reply Reply Quote 0
          • alfredoolivasA Offline
            alfredoolivas
            last edited by alfredoolivas

            82597122-f42d-4f60-81c5-e09c84883472-image.png

            Increases conversion of tryptophan into kynurenine pathway. Possibly reducing serotonin. Decreased catabolism too
            http://pubmed.ncbi.nlm.nih.gov/40858/

            HED: 0.13mg/kg TBA a day.

            alfredoolivasA 2 Replies Last reply Reply Quote 1
            • alfredoolivasA Offline
              alfredoolivas @alfredoolivas
              last edited by

              5904665a-1a48-4a5b-adb7-59dcac88d37d-image.png

              Methyl Tren increases fertility of females.
              https://pubmed.ncbi.nlm.nih.gov/528432/#:~:text=DOI%3A-,10.2527/jas1979.493729x,-No abstract available

              1 Reply Last reply Reply Quote 1
              • alfredoolivasA Offline
                alfredoolivas @alfredoolivas
                last edited by

                0.13mg/kg TBA a day was more effective than 2.5mg/kg TBA in supressing TAT.

                alfredoolivasA 1 Reply Last reply Reply Quote 1
                • alfredoolivasA Offline
                  alfredoolivas @alfredoolivas
                  last edited by

                  "in France, the average weight for seniors tends to be around 66-67 kg"

                  For these people, 7mg a day of tren would supress TAT by 30%. This is what Parabolan would deliver shortly after the first injection

                  sunsunsunS 1 Reply Last reply Reply Quote 0
                  • sunsunsunS Offline
                    sunsunsun @alfredoolivas
                    last edited by

                    interdasting

                    1 Reply Last reply Reply Quote 1
                    • alfredoolivasA Offline
                      alfredoolivas @engineer
                      last edited by alfredoolivas

                      @engineer bodybuilders are now starting to realise how powerful it is in low doses. Vigorous Steve was the one that put me onto this a year ago. Itโ€™s 8x more anabolic than testosterone, so of course they will abuse it and inject more.

                      1 Reply Last reply Reply Quote 0
                      • alfredoolivasA Offline
                        alfredoolivas
                        last edited by alfredoolivas

                        Lowers prolactin and GH as well as insulin the most.
                        1ae745f2-bb35-47f2-aa6e-1d30b0a78d53-image.png
                        https://www.cambridge.org/core/journals/animal-science/article/abs/effect-of-trenbolone-on-acetate-growth-blood-hormones-and-metabolites-and-nitrogen-balance-of-beef-heifers/8B3677C602A7E26F05252173EBBD474C

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                        • alfredoolivasA Offline
                          alfredoolivas
                          last edited by alfredoolivas

                          4c8871c5-287b-48c8-9a06-aa54ad7e0a1f-image.png

                          It decreases faty acid synthase, ACC in liver, adipose and muscle and LIPOLYSIS IN ADIPOSE TISSUE. It increases lipolysis in the liver and muscle, but allows adipose tissue to not release FFA into the blood!
                          10.1055/s-2007-1018919

                          1 Reply Last reply Reply Quote 0
                          • alfredoolivasA Offline
                            alfredoolivas
                            last edited by

                            Seems to make turkeys with weak legs more excitable, indicating it increases intracellular calcium
                            cfec36a0-9054-4353-aac0-d92faa12e3bc-image.png

                            10.1080/00071688108447879

                            alfredoolivasA 1 Reply Last reply Reply Quote 0
                            • alfredoolivasA Offline
                              alfredoolivas @alfredoolivas
                              last edited by

                              " the anabolic action of TP and TBA, especially in female rats, may be mediated through an antagonistic effect to the catabolic effects of oestrogens and glucocorticoids."
                              https://www.semanticscholar.org/paper/Effect-of-sex%2C-testosterone-propionate-and-acetate-Santidriรกn-Thompson/64ece3bf3a3cd424d83611cfad2d54f94912c41c

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                              • alfredoolivasA Offline
                                alfredoolivas
                                last edited by alfredoolivas

                                decreases FFA " Plasma triglyceride concentrations in all
                                implanted groups fell markedly by week 5 and remained well
                                below control values until slaughter. The concentration of
                                plasma non-esterified fatty acids decreased by approximately
                                50% in all four treatment groups
                                "

                                b6eb3ab6-0ebb-40ad-b7a7-ed03abace780-image.png

                                f4366e4a-b08a-4a61-95b5-1ff3cedf07b4-image.png

                                Low doses of tren & E2 had lower cholesterol.

                                https://pubmed.ncbi.nlm.nih.gov/7152469/

                                1 Reply Last reply Reply Quote 0
                                • alfredoolivasA Offline
                                  alfredoolivas
                                  last edited by

                                  "TB A also had no effect on either the digestibility or metabolizability of the energy in the diet, or on the total energy retained by the two experimental groups...there were significant differences in the way this energy was partitioned for growth between treated and control animals. "

                                  It doesn't cause fat loss via increasing metabolism?

                                  https://www.researchgate.net/publication/231925431_The_effect_of_trenbolone_acetate_on_growth_rate_and_carcass_composition_of_young_female_rabbits

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                                  • alfredoolivasA Offline
                                    alfredoolivas
                                    last edited by

                                    " Trenbolone, however, did not demonstrate any genotoxic effect in the assays performed."
                                    https://pubmed.ncbi.nlm.nih.gov/3090982/

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                                    • alfredoolivasA Offline
                                      alfredoolivas
                                      last edited by alfredoolivas

                                      a2097a76-0e88-4866-88ac-9d05c7ba9277-image.png
                                      Decreases fat cell size

                                      adef3e8f-aea9-457c-9d38-217b5e58d4a8-image.png
                                      Decreases FAS and increases G6PD and other genes involved with NADPH formation

                                      https://pubmed.ncbi.nlm.nih.gov/3583947/

                                      200mg TBA implant given once every 56 days with a 60 day withdrawal period.

                                      I am not going to even estimate the amount of tren built up and released lol

                                      But that is 3.57mg TBA (2.85mg elemental weight) every day given to Heifers, with a 60 day withdrawal period.
                                      9dd8310f-fc83-4fff-94fd-8a5140cc2e82-image.png

                                      French were giving 5mg a day to 65kg humans XDXD.
                                      Bro if 2.85mg of trenbolone can do this to a HEIFER after 60 days of no tren then imagine what 5mg does to a human @engineer

                                      alfredoolivasA 1 Reply Last reply Reply Quote 0
                                      • alfredoolivasA Offline
                                        alfredoolivas @alfredoolivas
                                        last edited by

                                        I think tren only cycles may be good, because OVX with tren was often more effective than tren by itself.

                                        Lowering endogenous sex steroids like progesterone, estradiol and test WITH tren can be even more anti-lipolitc.

                                        bee75c2e-c1dc-4265-a5b3-6727cd26da85-image.png

                                        alfredoolivasA 1 Reply Last reply Reply Quote 0
                                        • alfredoolivasA Offline
                                          alfredoolivas @alfredoolivas
                                          last edited by

                                          @sunsunsun my inuition may be correct๐Ÿ˜‰ ๐Ÿ˜‰

                                          @sunsunsun said in moggy chicken log:

                                          @alfredoolivas but why u think androstane avoidance is le good

                                          @alfredoolivas said in moggy chicken log:

                                          @sunsunsun intuition๐Ÿ˜‰

                                          sunsunsunS 1 Reply Last reply Reply Quote 0
                                          • sunsunsunS Offline
                                            sunsunsun @alfredoolivas
                                            last edited by

                                            @alfredoolivas y tho

                                            alfredoolivasA 1 Reply Last reply Reply Quote 0
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