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    The anti-cortisol mechanism of trenbolone

    Scheduled Pinned Locked Moved Literature Review
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    • alfredoolivasA Offline
      alfredoolivas
      last edited by

      Seems to make turkeys with weak legs more excitable, indicating it increases intracellular calcium
      cfec36a0-9054-4353-aac0-d92faa12e3bc-image.png

      10.1080/00071688108447879

      alfredoolivasA 1 Reply Last reply Reply Quote 0
      • alfredoolivasA Offline
        alfredoolivas @alfredoolivas
        last edited by

        " the anabolic action of TP and TBA, especially in female rats, may be mediated through an antagonistic effect to the catabolic effects of oestrogens and glucocorticoids."
        https://www.semanticscholar.org/paper/Effect-of-sex%2C-testosterone-propionate-and-acetate-Santidriรกn-Thompson/64ece3bf3a3cd424d83611cfad2d54f94912c41c

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        • alfredoolivasA Offline
          alfredoolivas
          last edited by alfredoolivas

          decreases FFA " Plasma triglyceride concentrations in all
          implanted groups fell markedly by week 5 and remained well
          below control values until slaughter. The concentration of
          plasma non-esterified fatty acids decreased by approximately
          50% in all four treatment groups
          "

          b6eb3ab6-0ebb-40ad-b7a7-ed03abace780-image.png

          f4366e4a-b08a-4a61-95b5-1ff3cedf07b4-image.png

          Low doses of tren & E2 had lower cholesterol.

          https://pubmed.ncbi.nlm.nih.gov/7152469/

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          • alfredoolivasA Offline
            alfredoolivas
            last edited by

            "TB A also had no effect on either the digestibility or metabolizability of the energy in the diet, or on the total energy retained by the two experimental groups...there were significant differences in the way this energy was partitioned for growth between treated and control animals. "

            It doesn't cause fat loss via increasing metabolism?

            https://www.researchgate.net/publication/231925431_The_effect_of_trenbolone_acetate_on_growth_rate_and_carcass_composition_of_young_female_rabbits

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            • alfredoolivasA Offline
              alfredoolivas
              last edited by

              " Trenbolone, however, did not demonstrate any genotoxic effect in the assays performed."
              https://pubmed.ncbi.nlm.nih.gov/3090982/

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              • alfredoolivasA Offline
                alfredoolivas
                last edited by alfredoolivas

                a2097a76-0e88-4866-88ac-9d05c7ba9277-image.png
                Decreases fat cell size

                adef3e8f-aea9-457c-9d38-217b5e58d4a8-image.png
                Decreases FAS and increases G6PD and other genes involved with NADPH formation

                https://pubmed.ncbi.nlm.nih.gov/3583947/

                200mg TBA implant given once every 56 days with a 60 day withdrawal period.

                I am not going to even estimate the amount of tren built up and released lol

                But that is 3.57mg TBA (2.85mg elemental weight) every day given to Heifers, with a 60 day withdrawal period.
                9dd8310f-fc83-4fff-94fd-8a5140cc2e82-image.png

                French were giving 5mg a day to 65kg humans XDXD.
                Bro if 2.85mg of trenbolone can do this to a HEIFER after 60 days of no tren then imagine what 5mg does to a human @engineer

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                • alfredoolivasA Offline
                  alfredoolivas @alfredoolivas
                  last edited by

                  I think tren only cycles may be good, because OVX with tren was often more effective than tren by itself.

                  Lowering endogenous sex steroids like progesterone, estradiol and test WITH tren can be even more anti-lipolitc.

                  bee75c2e-c1dc-4265-a5b3-6727cd26da85-image.png

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                  • alfredoolivasA Offline
                    alfredoolivas @alfredoolivas
                    last edited by

                    @sunsunsun my inuition may be correct๐Ÿ˜‰ ๐Ÿ˜‰

                    @sunsunsun said in moggy chicken log:

                    @alfredoolivas but why u think androstane avoidance is le good

                    @alfredoolivas said in moggy chicken log:

                    @sunsunsun intuition๐Ÿ˜‰

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                    • sunsunsunS Online
                      sunsunsun @alfredoolivas
                      last edited by

                      @alfredoolivas y tho

                      alfredoolivasA 1 Reply Last reply Reply Quote 0
                      • alfredoolivasA Offline
                        alfredoolivas @sunsunsun
                        last edited by alfredoolivas

                        @sunsunsun What are your questions?

                        It's really effective in quite low doses. Heifer to HED dose is pretty similar. If 2.85mg of TBA a day (the estimated amount when they were slaughtered) had 28% less FAS, smaller fat cells or 700mcg doses having 63% less GR expression & less cortisol, 2mg having 75% less GR in rats. It also decreases FFA & Lipolysis in fat, whilst having these moderate fat loss effcts in these low doses, which is quite rare.

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