@Peatly thank you so much
Latest posts made by vocedilegno
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RE: On Cellular Organization and Respiration
@Amazoniac wow, this is fantastic. Thank you so much
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RE: Estrogenic effects from t3 and progesterone
@Peatly by the way, your signature quote is absolutely fantastic and explains so much about certain people I’ve encountered in my life. Thank you
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RE: Cancer
@Ecstatic_Hamster this is fascinating. Where did you hear of this?
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RE: Estrogenic effects from t3 and progesterone
@Peatly looking it over again, it does seem that it’s from personal correspondence, doesn’t it. In which case I would agree that it’s likely a very context-specific advice to have the beta-blocker on hand
It’s always seemed clear to me that T3Uncoupled knows and loves Peat’s work more deeply than most of us, and that’s the only reason I didn’t question it or hunt down the primary source.
Corroborating the utility of the idea, a friend of mine experimented with T3 (Cynomel) for his high cholesterol not more than a couple of months ago at my suggestion and had very off-putting heart palpitations. That happened before I had come across the article we’re discussing, perhaps just before T3Uncoupled had published it.
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RE: How do you explain to normies that sugar is good for you?
@Ray-Peat-Fanboy this is a clear case-in-point of the CO2-climate change hypothesis as a depopulation psyop
On the other hand there is the question of which type of human contributes more CO2 to the ecosystem — the healthy person who also retains CO2 well, or the stressed person who blows too much of it out all the time?
Regarding the notion of CO2 as a Lewis acid, GE podcast episode 35 is one of my top candidates for best episode of all time
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RE: Estrogenic effects from t3 and progesterone
@Peatly I also heard it that progesterone is what prevents estrogenic activity of DHEA, not the other way around. I got the bit about Peat recommending beta blockers for first time T3 use from https://t3uncoupled.substack.com/p/thyroid-supplementation-simplified
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RE: Protein and the Randle cycle
@herayclitus check out Brad Marshall’s YouTube channel (fireinabottle). He shows how not even only tryptophan/methionine/cysteine slow metabolism as Ray said, but that BCAAs actually increase fat oxidation! Which can be a disaster in excess!!
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RE: How do you explain to normies that sugar is good for you?
@Ray-Peat-Fanboy if you are in a situation where you’re pressed to give a good defense of it, you could talk about how mitochondrial glucose oxidation generates much more CO2 than fat oxidation, and how CO2 is a Lewis acid fortifying the acidity of the amino acids which constitute the proteins which make up the tissues and organs of the body. (Generative Energy #35)
Defending sugar against starch you could bring up endotoxin and big insulin swings which cause hypoglycemic stress and aromatase activation, for example. But then that leads to the “estrogen is bad” conversation which is another uphill battle