Vitamin A increases T3 by more than 60% in humans!
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This study shows a beneficial effect of 25 000 IU of Retinyl palmitate on thyroid markers, meaning increased T3 and lowered TSH.
It's interesting that the rat study (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9596568/#:~:text=The findings demonstrated that long,Dio1 and Dio3 expression levels) found negative effects and the human study positive effects at a similar dosage.
But since human studies are higher up in the evidence pyramide, I tend to interpret this as Vitamin A beeing good for thyroid in reasonable dosages.The effect was especially pronounced in nonobese individuals where T3 increased by more than 60%!
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M Mauritio referenced this topic on
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Theory checks out. Just ate liver and feel very good, very high thyroid feeling.
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Some dude posted this study on RPF. In rats, an equivalent dose was enough increases TSH and suppress T3. I personally experienced that anything over an extra 5.000IU can be suppressive for a mildy hypothyroid person.
https://link.springer.com/content/pdf/10.1007/s00394-022-02945-5.pdf
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Liver is really the only tame way for me to get vitamin A. I have Haidut's Retinil (retinyl acetate), but it causes what I can only describe as severe joint and bone pain. Maybe missing co-factors are a contributor, but I'm so tired of feeling bad from supplements that I've resolved to stick with liver as my source for A. Nothing against Haidut's products — which I have several of.
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Interestingly in this study it looks like RBP levels decreased and so did TTR.
What would be the mechanism of action here since both thyroid and vitamin A levels increased you would expect their carrier proteins to as well no?
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Do you have a link to this study?
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@Kvothe said in Vitamin A increases T3 by more than 60% in humans!:
Some dude posted this study on RPF. In rats, an equivalent dose was enough increases TSH and suppress T3. I personally experienced that anything over an extra 5.000IU can be suppressive for a mildy hypothyroid person.
https://link.springer.com/content/pdf/10.1007/s00394-022-02945-5.pdf
Well that dude (sinatra) probably has the study from this thread here (https://bioenergetic.forum/post/12395) where I posted it a few days before him, it's interesting that he did not post the main study of this very thread or any of the other pro-vitamin A things I posted.
The HED of about 30k IU per day is still realtively high. And i agree that this can make you hypo, which peat has said for decades.
On the other hand the study, which this thread is about (human study, not rat) shows clear benefits in a similar dosage.
