The relation between vitamin B6 and the unsaturated fatty acid factor
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Peat said that the Burrs study (where they gave rats a PUFA-free diet) were actually a Vitamin B6 deficiency. The whole thing can be found here: https://youtu.be/Oc1ijSN220k?si=Evj_3i_T-fwjeRgi.
They conducted an experiment in 1938 giving the rats moderate-high doses of B6 on that diet: https://www.sciencedirect.com/science/article/pii/S0021925818740386?ref=pdf_download&fr=RR-2&rr=8749d4922a114534. And it failed miserably, only giving the rats PUFA was the cure.
Does that suggest there is a minimum of PUFA for the organism to function? I can't seem to find any answers. Was Peat wrong about avoiding them completely?
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@peatolish i think he said it was like an insane small amount of PUFA that is important for the organism.
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@Nikolai I think you are just putting words in his mouth. He said that polyunsaturated fatty acids are not essential at all.
He also said that restoring the metabolic function uses up more nutrients (hence why he argued that it was a B6 problem). My hypothesis is that bringing the metabolic rate up, the rats got deficient in some other vitamin/mineral like zinc, and they didn't test that.
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@peatolish could be possible
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@Nikolai Another problem of this study is that they fed the rats halibut fish oil.
The rats could also get deficient in biotin.
This study was done poorly, it does not confirm any side of the argument.
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"All of the 9 animals which received no essential fatty acid showed development of scaly paws within 2 weeks after the initiation of the ad libitum feeding...
It should be noted that in the 9 animals which received no source of linoleic acid scaliness of the paws disappeared spontaneously, and within 66 days from the start of ad libitum feeding these animals, all of which had shown this symptom, were completely cured. The other skin lesions, when present, cleared much earlier.
This spontaneous disappearance of skin lesions within several weeks and paw scaliness within 66 days was again observed in a similar experiment carried out later with approximately the same number of animals on fat free ration A"
https://journals.sagepub.com/doi/abs/10.3181/00379727-66-16128
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Didn’t Ray say your body will produce mead acid (omega-9) in the presence of a PUFA deficiency
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Yes, he did.
"When dietary PUFA are not available, the body produces a small amount of unsaturated fatty acid (Mead acids), but these do not activate cell systems in the same way that plant-derived PUFAs do, and they are the precursors for an entirely different group of prostaglandins."
