Estrogenic effects from t3 and progesterone
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@pineapple said in Estrogenic effects from t3 and progesterone:
@Mauritio what did you do to tolerate t3? Im skinny but cant handle even a dose smaller than what you mentioned, get same side effects. Now that you tolerate it better, what benefits is it giving you? did you solve any health problems with using t3? The whole idea from what I read is it should reduce estrogenic symptoms and edema, so I can't really figure out how it does the opposite in some people
For me it was improving liver health by loosing weight.
It increased my life quality a lot: increased energy while lowering adreanline, increased calories I could eat by about 20-30%, increased mood, lowered edema, better hormonal health, etc... all of those and probably more.
It gives you the estrogenic symptoms because it is not beeing metabolized properly. Im not sure what exactly it is, but too much T3 gives me hypothyroid symptoms and that seems to be happening to you, too. (Maybe its reverse T3?)
Thats why Ray was often talking about the RIGHT amount of thyroid that will do xyz, because the wrong amount can either cause no improvement or even worsening. T3 dosage is not easy to figure out for some people. -
@vocedilegno said in Estrogenic effects from t3 and progesterone:
@Peatly looking it over again, it does seem that it’s from personal correspondence, doesn’t it. In which case I would agree that it’s likely a very context-specific advice to have the beta-blocker on hand
It’s always seemed clear to me that T3Uncoupled knows and loves Peat’s work more deeply than most of us, and that’s the only reason I didn’t question it or hunt down the primary source.
Corroborating the utility of the idea, a friend of mine experimented with T3 (Cynomel) for his high cholesterol not more than a couple of months ago at my suggestion and had very off-putting heart palpitations. That happened before I had come across the article we’re discussing, perhaps just before T3Uncoupled had published it.
T3uncoupled does seem passionate about Ray’s work. This is a good thing.
Your friend’s heart palpitation could be a result of the sudden demand on magnesium induced by taking thyroid. Dr. Peat has spoken about this often:
"Traditional thyroid doctors like Broda Barnes usually started with 30 milligrams of a well-standardized product, like at that time it was Armour thyroid. But I have seen two people who reacted very surprisingly to 15 milligrams, a fourth of a grain, with heart pain, and I realized what's happening is that your cells, especially your big muscle cells, retain magnesium and calcium in a balance. Calcium is a relaxant, and thyroid is needed for the muscles to retain the proper amount of magnesium, and your heart has that same magnesium-retaining, stabilizing effect when your thyroid is good. But if you're suddenly increasing the thyroid when you've been deficient, your muscles, your leg muscles will compete with your heart muscles for that trace of magnesium in your diet, and your heart arteries will constrict and you'll get a heart pain. So it's very important to make sure that your diet includes plenty of magnesium when you're starting to use thyroid." Ray Peat
Magnesium controls autonomic dysfunction by reducing adrenaline release. Ref
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@vocedilegno said in Estrogenic effects from t3 and progesterone:
@Peatly by the way, your signature quote is absolutely fantastic and explains so much about certain people I’ve encountered in my life. Thank you
Dr. Peat was aware of the absurdity of science – ‘the science’ a la Fauci is a good example. I think his sense of humour kept him sane. I will leave that signature here because when I change it, again, it will disappear from my posts.
"Humour is something that is lacking in ordinary science. They can't afford the amount of truth that's needed to experience humour." Ray Peat
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@Peatly thank you so much