How to esterize DHT at home? DIY
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Russian Star Peptides/Titan Chem seems to have finished DHT heptanoate (enanthate) oil but it's most likely bunk, since these guys are known scammers. Someone on RPF claimed their DHT gel contained caffeine and finasteride lmao. And someone on reddit actually tested it with Jano and it had no DHT.
But im a bit tempted to buy it and test it just out curiosity. -
@pannacottas said in How to esterize DHT at home? DIY:
Also i wouldn't use Test without DHT. Yes the skin has higher 5-AR expression bla bla, all i know is topical pansterone was very estrogenic for me. So i won't mess with aromatizable steroids, for now at least.
What's your diet like? Vitamin D, E, calcium, protein, salt, zinc, progesterone are all important to keep the right supply of androgens to estrogen. Lower more frequent dosing of T can prevent a rise in estrogen without the use of any aromatase inhibitors.
I actually take 100mg twice daily, but I also use an OTC aromatase inhibitor. But you probably wouldn't need this if you use the transscrotal method of delivery. As demonstrated in this study, physiological doses as small as 15mgs daily was enough to raise both T and DHT without effecting estradiol.
"The need for improved controlled delivery of testosterone to hypogonadal men stimulated the development of a self-adherent transscrotal testosterone system to provide programmed testosterone delivery through the uniquely permeable scrotal skin. In this short- and long-term efficacy trial, the responses of testosterone and its metabolites to the application of transscrotal testosterone systems of varying testosterone content were compared with the response to 200 mg of testosterone enanthate. Daily transscrotal testosterone system administration resulted in a rapid increase of testosterone and bioavailable, nonsex hormone binding globulin-bound testosterone levels to normal, peaking at two hours, followed by a slow decline over 23 hours, resembling the diurnal variation of endogenous testosterone. One year of daily transscrotal testosterone system therapy demonstrated continued reliable absorption of testosterone and suppression to normal of the luteinizing hormone in two of three patients. There was a greatly disproportionate increase of serum dihydrotestosterone over testosterone, suggesting 5-alpha reduction at the scrotal site. The subjects reported marked subjective improvement. Thus, the transscrotal testosterone system is a novel, effective, and well-tolerated method of delivering testosterone to hypogonadal patients."
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I've seen very similar studies as well but using slightly higher dosages, like 25mg and 50mg. The 50mg might be getting kinda high if you're trying not to disturb your E2, but long-term usage at 25mg will likely not be an issue either.
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Just to clarify, if you're wondering why I don't use the scrotal method and instead opt for normal dermal areas like shoulders, traps, forearms, etc. it's because I don't like waiting for it to dry on my balls before pulling up my pants. This is the only downside in my opinion, but if you have time to let it do it's thing, then this is the method I highly recommend.
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@pannacottas said in How to esterize DHT at home? DIY:
Russian Star Peptides/Titan Chem seems to have finished DHT heptanoate (enanthate) oil but it's most likely bunk, since these guys are known scammers. Someone on RPF claimed their DHT gel contained caffeine and finasteride lmao. And someone on reddit actually tested it with Jano and it had no DHT.
But im a bit tempted to buy it and test it just out curiosity.Do you mean this product? Looks kind of sus. Even if it's real I would never trust ordering controlled substances with my card or paypal. If they have a crypto option then fine, but they just mention card and paypal in their payment section.
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If transdermal T aromatizes easily then maybe I should try taking it. I'm even doing straight transdermal estrogen and that isn't doing jack to help my low E symptoms. I guess I will have to revisit the transdermal T thread and learn the tricks.
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As demonstrated in this study, physiological doses as small as 15mgs daily was enough to raise both T and DHT without effecting estradiol.
That's interesting, thanks.
Yeah i agree scrotal method is quite annoying. Also Ray has recommended against applying substances there. Since the skin is so thin, whatever you put will be absorbed highly; though i think the problem has to do more with the carrier than the hormones.Do you mean this product? Looks kind of sus. Even if it's real I would never trust ordering controlled substances with my card or paypal. If they have a crypto option then fine, but they just mention card and paypal in their payment section.
Yes that one. I think he's in the UK where steroids are in a gray zone between legal and controlled, but yeah if they dont have crypto then im not buying anything
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@Crypt-Keeper
Going off topic here but Ray didnt think there was such thing as "low estrogen". From what i've seen these symptoms can be low pregnenolone symptoms, among other things. Low blood estrogen can mean high tissue estrogen and high prolactin, btw. -
@pannacottas said in How to esterize DHT at home? DIY:
Also Ray has recommended against applying substances there. Since the skin is so thin, whatever you put will be absorbed highly; though i think the problem has to do more with the carrier than the hormones.
Yeah it's the solvent/carrier that's typically the issue. Although I suppose if you get a batch of T with exceptionally high contaminants that would also be bad. But generally speaking it's a carrier issue. Fortunately normal T base dissolves well in most things.
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@Crypt-Keeper said in How to esterize DHT at home? DIY:
If transdermal T aromatizes easily then maybe I should try taking it. I'm even doing straight transdermal estrogen and that isn't doing jack to help my low E symptoms. I guess I will have to revisit the transdermal T thread and learn the tricks.
Boron, d-aspartic acid, and saw palmetto would be a good (?) stack to raise estrogen. Also copper, so eat plenty of liver. Get your estrogen tested first, don't just assume based on symptoms alone. Raising estrogen would be too risky without knowing for sure. Edema, clots, stroke, cancer, erectile dysfunction are all a possibility from high estrogen.
