Girlfriend going off Hormonal Birth Control and Anti-Depressants for First Time in Half a Decade. Any Advice for Her.
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Ray Peats email response to getting off antidepressant use.
[Weaning off anti-depressants] Keeping the metabolic rate and cholesterol up is important, so that repair and adaptation will be quick. Progesterone reduces pain and anxiety, and pregnenolone would be the most convenient supplement for men, but it's hard to find products without allergens. Combining progesterone and DHEA or testosterone can produce the stabilizing effect without suppressing the libido. Benadryl and cyproheptadine are probably both helpful. Withdrawal from morphine and SSRIs and migraine involve some similar processes.
I knew someone who had been addicted to morphine and alcohol for 30 years, who was drinking quarts of beer and wine daily when he didn't have morphine, who had an opportunity for a good job if he could get sober. Starting progesterone at bedtime (and stopping the wine), he said it was the first time he didn't have a hangover in the morning. He used enough progesterone to neuter most people, but said it didn't affect his sex function; he was taking a lot of Cytomel and magnesium, but wasn't drunk again as long as I knew him, and his general health improved.
It depends on how much pregnenolone you can assimilate. People would use progesterone in amounts needed to stop the withdrawal symptoms, but pregnenolone doesn't have the powerful effects of progesterone, even in multi-gram quantities, so it's just a matter of seeing what it can do. As I understand the mechanism (migraine, withdrawal, etc.), estrogen-histamine-serotonin rise on a background of hypothyroid liver malfunction, cytomel (and/or sugar, selenium, B vitamins) allows the liver and other detoxifying systems to lower them, and the lower they are, the less progesterone or pregnenolone it takes to block the symptoms.
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Read Ray Peats articles on serotonin.
Ssri increase serotonin.HAIDUT has recommended cyproheptadine to help get off ssri
Comment from another site:
"Note to others; I received several PMs who found cyproheptadine very useful after discontinuing SSRIs. " -
If the nutritional foundation is good I would add in Progest e during luteal phase to make up for all the years progesterone production lost
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@SpicyPeater do you know a good vitamin A supplement in the UK
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Can confirm. It took me about 6 years to quit long term Effexor use. What I've gathered from years of reading accounts is that a few lucky people seem to be able to quit easily, some have a rough few weeks and most have years long protracted withdrawal.
Everyone wants to believe they are in group one or two, so nothing I say here is most likely going to influence your decision to taper quickly. Just know that if she starts to get severe psychological symptoms of depression, hopelessness and terror, it's probably withdrawals. At that point the best option is to reinstate the AD, then plan to taper at a rate of 10% per month.
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@PunkinEater, yes, I took the same ssri and weaned off in about a year. I started by cutting the pill in quarters. I would take 3 of the quarters, and then half of the last quarter. I would go at least a month on that reduced dose, and then take off a little more. It went pretty good, considering the drug that I was getting off of.
I wish I had the Ray peat advice at the time I did it to take some progest-e.
My advice is don't rush it.
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Since she ended up on an ssri, you might find some good info on Haidut page for ssri topics
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As far as birth control, I went on and off them several times without any perceived problem.
Everyone might be different.
Knowing what I know now, I would never take them. I advise any young woman not to take them.
As stated above, I would get some progest-e and take it in a cyclic rhythm in line with the cycle.
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@Sunniva Hi Fren!
At first I cut over three months and everything went fine. About a month after my last dose I went completely nuts with non-stop panic/terror/horror attacks. That lasted a few months until I reinstated a partial dose. From there I cut 10% per month which took a few years.
I can't say the progestE really does anything for me. The only thing that seems to help is diphenhydramine. I still have trouble sleeping through the night, but it's not too bad. I also get claustrophobic attacks from time to time.
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Low doses of Cyproheptadine. (Work your way up from .5 to 2mg /night)
Progest-E
Thiamine (recommend benfothiamine)
Egg Yolks
Cook with coconut oil
Fresh fruit
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@PunkinEater drop diphenhydramine for Cyproheptadine. Less side effects and better for fixing serotonin system dysfunction.
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Hopefully your relationship survives her coming off BC, I’ve heard many horror stories.
