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    What is your favourite substance/ supplement for reducing cortisol?

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    • ?
      A Former User
      last edited by

      What is your favourite substance/ supplement for reducing cortisol?

      yerragY serotoninskepticS ? 3 Replies Last reply Reply Quote 0
      • T
        tartaria
        last edited by

        It's gotta be cyproheptadine, or high dose L theanine can go the trick

        ? 1 Reply Last reply Reply Quote 0
        • L
          LetTheRedeemed
          last edited by LetTheRedeemed

          I second cypro... I want to add that I believe I've experienced success with high dose gelatin (due to glycine directly lowering cortisol).

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          • ?
            A Former User @tartaria
            last edited by

            @tartaria

            Any major side effects from cyproheptadine?

            I’ve seen studies showing ashwaganda nuking cortisol, but I don’t like the way it feels, almost seretonergic

            T 1 Reply Last reply Reply Quote 0
            • T
              tartaria @A Former User
              last edited by

              @RawGoatMilk88 This has been my experience with cypro.

              Dosage of 1-2mg.

              15 minutes after sublingual administration I feel energetic, light/airy, more likely to crack dry jokes but less overall emotion. Increased concentration, my desire to accomplish something goes up.

              These effects continue till around 2-3 hour mark when I start to get very hungry and fairly tired, however relaxed.

              Sleep can only be described as sinking into a cloud. Very cozy + vivid dreams. I sleep a long time on cypro, and it's hard to get up in the morning because of the reduced cortisol.

              Once I'm awake I chug some orange juice and my energy floods back, spurred on by thyroid rather than typical cortisol morning spike

              The biggest benefit comes 24-48 hours later when I get a dopamine rebound. due to the fact that cypro lowers 5ht-2 seretonin substantially, and dopamine slightly, this causes a rebound the following next two days when I receive a large boost in dopamine.

              The largest side effects would be caused by too high of a dose or taking cypro too frequently instead of as a tool. A 2mg+ dose can cause a LARGE decrease in 5ht-2, and you can feel a total lack of emotions. When I experimented with larger doses I felt like a robot with a high work ethic and zero social anxiety, and yet I felt very disconnected from the real world.

              L 1 Reply Last reply Reply Quote 0
              • yerragY
                yerrag @A Former User
                last edited by yerrag

                @RawGoatMilk88

                Not a substance but a process.

                It is to make your blood sugar stable by knowing how to manage your food intake by blending your macros well and choosing the right kind of carbs to blend with protein and fat intake. And the implementing and monitoring and tweaking as you go.

                Doing it right means that even if you're prone to sugar highs and sugar lows, because you can't really absorb and metabolize sugar optimally, you can still make your blood sugar stay in a narrower range such that you don't get very high spikes and you don't crash either. You thus minimize the secretion of insulin, a stress hormone, which is strongly branded as a savior rather than a villain. Making an enemy your friend is the worst way to be in good graces.

                Insulin converts blood sugar to fat, and it inhibits lipolysis, a nice dynamic duo to make you overweight and obese.

                The answer is not to increase insulin sensitivity, which really means nothing as I cannot even effing understand what it means. It is to to make insulin irrelevant really, by disappearing it as much as you can. But that is the goal, though not feasible nor practical. But by minimizing the effect of insulin, you have to make your blood sugar stable, and because of insulin being low, you don't get to be low in blood sugar as much, as it is low blood sugar that really harms, not high blood sugar.

                When blood is low in sugar, and when you have little or no glycogen reserves, you would have to rely on cortisol to trigger the conversion of body protein to sugar.

                Temporal thinking is the faculty that’s
                engaged by an enriched environment, but it’s
                wrong to call it “thinking,” because it’s simply
                the way organisms exist... - Ray Peat Nov 2017 Newsletter

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                • L
                  LetTheRedeemed @tartaria
                  last edited by

                  @tartaria
                  It reads like Peat fan fiction lol

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                  • D
                    djledda
                    last edited by

                    If you can get your hands one pure good quality pregnenolone then half a gram to a gram of that will obliterate any stress. Saved me on a few occasions.

                    1 Reply Last reply Reply Quote 0
                    • serotoninskepticS
                      serotoninskeptic @A Former User
                      last edited by

                      @RawGoatMilk88 said in What is your favourite substance/ supplement for reducing cortisol?:

                      What is your favourite substance/ supplement for reducing cortisol?

                      Salt!

                      1 Reply Last reply Reply Quote 0
                      • ?
                        A Former User @A Former User
                        last edited by

                        @RawGoatMilk88 Sugar, salt and nutritious food.

                        Also, while we're on the topic of reducing cortisol: deep breathing, sunlight on bare skin, long pleasant walks, sleep and talking to loved ones.

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                        • JenniferJ
                          Jennifer
                          last edited by

                          Ice cream.

                          I have stood on a mountain of no’s for one yes. ~ B. Smith

                          serotoninskepticS L 2 Replies Last reply Reply Quote 0
                          • serotoninskepticS
                            serotoninskeptic @Jennifer
                            last edited by

                            @Jennifer Second this

                            1 Reply Last reply Reply Quote 0
                            • L
                              LetTheRedeemed @Jennifer
                              last edited by

                              @Jennifer said in What is your favourite substance/ supplement for reducing cortisol?:

                              Ice cream.

                              based

                              1 Reply Last reply Reply Quote 0
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