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Twitter fad fixating on Deuterium and carb seasonality? What's the deal?

Bioenergetic Development
mitochondria deuterium fat oxidation twitter
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    eduardo-crispino @NNight
    last edited by 19 days ago

    @NNight yeah it's created when making heavy water . why is it even a question you are asking

    N 1 Reply Last reply 19 days ago Reply Quote 0
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      eduardo-crispino @dapose
      last edited by eduardo-crispino 19 days ago 19 days ago

      @dapose you're making an assumption that the idea is not valid because of "marketing forces" . deuterium depletion has been studied and talked about for awhile, it didn't just come out because of Jack Kruse forum. If there's a marketing aspect to it (turning waste product from heavy water manufacture into a boutique health product), that is just one aspect of it to keep in mind when evaluating biased claims, it's not a good excuse to neglect the whole idea.

      there is a quality difference between glacier water near its melt source vs. coastal rain water used as a drinking water or to grow plants

      D 1 Reply Last reply 19 days ago Reply Quote 0
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        dapose @eduardo-crispino
        last edited by 19 days ago

        @eduardo-crispino said in Twitter fad fixating on Deuterium and carb seasonality? What's the deal?:

        @dapose you're making an assumption that the idea is not valid because of "marketing forces" . deuterium depletion has been studied and talked about for awhile, it didn't just come out because of Jack Kruse forum. If there's a marketing aspect to it (turning waste product from heavy water manufacture into a boutique health product), that is just one aspect of it to keep in mind when evaluating biased claims, it's not a good excuse to neglect the whole idea.

        there is a quality difference between glacier water near its melt source vs. coastal rain water used as a drinking water or to grow plants

        Nano motors on mitochondria… Ray talked about trying to understand electrons his whole life. Trying to make a model a picture of what they were doing in different situations etc… and talked about how most people especially people that market products as narrowly focusing on flawed models narrow science, fraudulent or just stupid. He talked about this in almost every food from coconuts to coke to calcium to corn…. Manufacturing supplements, he points out endless ways that good substances can be made toxic and poison you. So, deuterium. You think I should work on that? I’ve heard people lecture on it for 9 years and it just well, seems like horse shit to me. I mean I care about horse manure more than I care about deuterium. RO water vs Structured water, that’s a topic! Nano motors on mitochondria…it’s not observable. How sweet my OJ is, is observable. How my stomach reacts to RO water vs Salted water… observable. Most people have 1000 chemicals in their tap water that they drink every day. And they are fine. I work with them. I don’t drink that water because I can perceive a quality to the water I make.
        Tom Cowan was talking about deuterium many years ago for cancer therapy etc.
        last point I guess is that there are 100 things someone could work on to improve thier health before you need to lighten your waters isotopes.

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          NNight @eduardo-crispino
          last edited by 19 days ago

          @eduardo-crispino said in Twitter fad fixating on Deuterium and carb seasonality? What's the deal?:

          @NNight yeah it's created when making heavy water . why is it even a question you are asking

          Do you know the process of deuterium depleted water production or do you make a guess?

          It's a question because it is central to the comparison with fish oil, and his theory?!

          E 1 Reply Last reply 19 days ago Reply Quote 0
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            eduardo-crispino @NNight
            last edited by 19 days ago

            @NNight I think the main way is to bubble some type of gas through the water, there are probably some other methods that use a lot of electricity and aren't cost effective yet.

            the other poster mentioned fish oil to compare it to the fish oil marketing scam and I don't think that's fair considering deuterium depleted water has potential health benefits that haven't been thoughtfully refuted like they have for fish oil

            N 1 Reply Last reply 19 days ago Reply Quote 0
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              NNight @eduardo-crispino
              last edited by NNight 19 days ago 19 days ago

              @eduardo-crispino said in Twitter fad fixating on Deuterium and carb seasonality? What's the deal?:

              the other poster mentioned fish oil to compare it to the fish oil marketing scam and I don't think that's fair considering deuterium depleted water has potential health benefits that haven't been thoughtfully refuted like they have for fish oil

              I'm just saying that his argument (or a part of it) is probably based on false premises and that you are confirming it without seemingly solid knowledge of the production processes.

              My opinion:

              • I think DDW can be useful for some diseases (cancer especially),
              • Deuterium is considered bad for the production of energy but it can also be useful for other biological processes (collagen/bone production),
              • accumulation of deuterium, or bad "fractionation", has probably deeper root causes than consumption of deuterium itself.

              An interesting hypothesis:

              The amino acid proline has unique properties that make it ideal for trapping deuterium, and we argue that peptidyl prolyl isomerases facilitate deuterium trapping in proline residues of proline-rich proteins, which are especially common as structural proteins in the extracellular space. The endothelial glycocalyx supports deuterium trapping in the gelled water maintained by the highly sulfated heparan sulfate molecules found there. The so-called exclusion zone (EZ) water in the glycocalyx releases protons preferentially into the circulation, generally leaving behind the deuterons, which strengthen the gel and the collagen matrices. Deficiencies in sulfation in the glycocalyx lead to weakening of the battery maintained by the gelled water, ultimately resulting in higher levels of deuterium circulating in the blood. It is possible although still speculative that proline-rich intrinsically disordered proteins (IDPs) fractionate deuterium out of the medium and sequester it in the “misfolded” oligomers and fibrils that are a feature of neurodegenerative diseases such as Alzheimer’s.

              Is Deuterium Fractionation a Major Controlling Factor in Human Metabolism and Cancer? An Essential Role for Proline
              https://www.preprints.org/manuscript/202406.1284/v1

              N E 2 Replies Last reply 19 days ago Reply Quote 0
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                NNight @NNight
                last edited by 19 days ago

                Overall, a pattern emerges that suggests that the cells are able to somewhat independently control deuterium levels in the water in different compartments so as to optimize metabolic health. To a first approximation, it appears that the cell strategizes to maintain deupleted water in the major organelles, most especially the mitochondria, but also the endoplasmic reticulum (ER), the peroxisome, the lysosomes and the nucleus. In parallel, as we will argue later on, the cell likely sequesters deuterium in the collagen molecules and gelled water in the extracellular matrix, particularly in the bone [18]. Deuterium doping actually strengthens bone, whereas deuterium is toxic to the mitochondrial ATPase pumps, so such a strategy is consistent with metabolic needs.

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                  eduardo-crispino @NNight
                  last edited by eduardo-crispino 18 days ago 18 days ago

                  @NNight are you autistic ?

                  N T 2 Replies Last reply 18 days ago Reply Quote 0
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                    NNight @eduardo-crispino
                    last edited by 18 days ago

                    @eduardo-crispino you're blocked.

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                      ThinPicking
                      last edited by 18 days ago

                      There's a gem in this thread.

                      D 1 Reply Last reply 16 days ago Reply Quote 0
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                        ThinPicking @eduardo-crispino
                        last edited by 18 days ago

                        He has colloidal expertise. That's why he can fly.

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                          ThinPicking
                          last edited by 18 days ago

                          Can anyone link me to an example on twitter? I'd like to PCR test the participants.

                          N 1 Reply Last reply 17 days ago Reply Quote 0
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                            NNight @ThinPicking
                            last edited by NNight 17 days ago 17 days ago

                            This post is deleted!
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                              dapose @ThinPicking
                              last edited by 16 days ago

                              @ThinPicking said in Twitter fad fixating on Deuterium and carb seasonality? What's the deal?:

                              There's a gem in this thread.

                              You are too kind. 😁

                              T 1 Reply Last reply 16 days ago Reply Quote 0
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                                ThinPicking @dapose
                                last edited by 16 days ago

                                Well, there is that too.

                                Is that cat still with you @dapose? My memory isn't photographic, but I remember a cat.

                                D 1 Reply Last reply 16 days ago Reply Quote 0
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                                  dapose @ThinPicking
                                  last edited by 16 days ago

                                  @ThinPicking haha! Yes! He’s the best! Still kicking ass!
                                  I’d post a pic of him but I can’t figure out how to upload pics on this forum. Other than my
                                  Little profile gif.

                                  T 1 Reply Last reply 16 days ago Reply Quote 0
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                                    ThinPicking @dapose
                                    last edited by 16 days ago

                                    Excellent ☺

                                    That'll do.

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