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    Vitamin E, A, B3 and T4 are androgenic and potentiates the effects of testosterone. Estrogen, aldosterne & cortisol may do the opposite.

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    • alfredoolivasA Offline
      alfredoolivas @engineer
      last edited by

      @engineer Yes would love to try out mega doses of the fat soluble vitamins but their long half life scares me from doing it lol. It would take like a year to clear out the dosages because they are so fat soluble lol.

      alfredoolivasA 1 Reply Last reply Reply Quote 0
      • alfredoolivasA Offline
        alfredoolivas @alfredoolivas
        last edited by

        It could be worth it. 1 year of worse health or I find a cornucopia of health.

        engineerE 1 Reply Last reply Reply Quote 0
        • engineerE Offline
          engineer @alfredoolivas
          last edited by engineer

          @alfredoolivas if it makes you feel better I have taken 25k/d IU of beta carotene for a year+ and am feeling zero bad effects from it

          alfredoolivasA 1 Reply Last reply Reply Quote 1
          • alfredoolivasA Offline
            alfredoolivas @engineer
            last edited by

            @engineer W. But why? Living in florida makes you tanned, I think the addition of beta carotene would make you look like Trump XD

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            • engineerE Offline
              engineer @alfredoolivas
              last edited by engineer

              @alfredoolivas I actually started taking beta carotene before I knew anything about supplements much less Ray Peat, it was my mom who got it because it was cheap and looked effective.

              My skin doesnt look orange at all but does change in tone drastically depending on the lighting:

              4374.jpg

              4372.jpg

              So, it's possible to take in that much and be fine, but that's only me.

              alfredoolivasA 1 Reply Last reply Reply Quote 0
              • alfredoolivasA Offline
                alfredoolivas @engineer
                last edited by

                @engineer Nice. Vitamin A seems really important in the androgenic system. Along with 14mg of Iron, it was as effective than 5mg of oxandrolone or 25mg of T at increasing the height of children, at only 4000IU a week!

                https://pubmed.ncbi.nlm.nih.gov/15163330/

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                • engineerE Offline
                  engineer @alfredoolivas
                  last edited by engineer

                  @alfredoolivas Unfortunately I have to dissent again because my height is below "average", possibly due to high estrogen. Thankfully that's no longer an issue thanks to Peating but I always wonder what would be different if I had known about RP back then.

                  Was high estrogen not an issue for the children receiving T in that study?

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                  • alfredoolivasA Offline
                    alfredoolivas @engineer
                    last edited by

                    @engineer it was 100mg a month which would create a huge spike and an uneven distribution of testosteorne throughout the month, because testosterone cypionate was used. So 72mg of elemental testosterone would give a very rough amount of maybe 2.4mg ot T delivered a day, with a lot more being delivered at the first few weeks.

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                    • jamezb46J Offline
                      jamezb46 @alfredoolivas
                      last edited by

                      @alfredoolivas So a product combining T + A + E + t4 + t3 would give a good kick in the pants, would it?

                      In time there is life but no knowledge; outside time there is knowledge but no life

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                      • alfredoolivasA Offline
                        alfredoolivas @jamezb46
                        last edited by

                        @jamezb46 yes and adding 10mcg of melanotan II would be super effective
                        https://bioenergetic.forum/topic/9088/microgram-doses-of-melanotan-ii-may-increase-the-androgenic-effects-of-testosterone

                        engineerE 1 Reply Last reply Reply Quote 0
                        • engineerE Offline
                          engineer @alfredoolivas
                          last edited by engineer

                          @alfredoolivas Or Pansterone + Kuinone + Androsterone on you-know-where in addition to A + E + T3 + T4 + melanotan II?

                          Just imagine the possibilities

                          alfredoolivasA 1 Reply Last reply Reply Quote 0
                          • alfredoolivasA Offline
                            alfredoolivas @engineer
                            last edited by alfredoolivas

                            @engineer I assume you mean the scrotum. That's not a great idea, because it would increase androgen sensitivty of the testicles.

                            You don't want your testicles to be androgen sensitive because that would increase the negative feedback loop T & DHT, has on T production, lowering T production.

                            I saw that you apply androsterone there? I think this is counterproductive. It would increase local DHT in your testicles, reducign the amount of T produced by them.
                            You want your testicles to have sensitive LH receptors, not androgen receptors.

                            @jamezb46 correct?

                            If you mean on your penis? great idea. Especially considering the vitamins are fat soluble and may gather there, extending their half lives on the penis.

                            engineerE 1 Reply Last reply Reply Quote 0
                            • engineerE Offline
                              engineer @alfredoolivas
                              last edited by engineer

                              @alfredoolivas said in Vitamin E, A, B3 and T4 are androgenic and potentiates the effects of testosterone. Estrogen, aldosterne & cortisol may do the opposite.:

                              I saw that you apply androsterone there? I think this is counterproductive. It would increase local DHT in your testicles, reducign the amount of T produced by them.
                              You want your testicles to have sensitive LH receptors, not androgen receptors.

                              Are you saying that the goal should be to bring DHT in the scrotum to the minimum needed? If so, does that mean you have to constantly monitor and adjust androsterone/AIs elsewhere to fine tune the DHT/estrogen balance? This is getting complicated now because estrogen is a more powerful negative HPG trigger than DHT.

                              alfredoolivasA 1 Reply Last reply Reply Quote 0
                              • alfredoolivasA Offline
                                alfredoolivas @engineer
                                last edited by

                                @engineer I wouldn't call it a goal, because high endogenous production of T would cause scrotal T+DHT to be high. But there is no benefit of adding androgenic or estrogenic substances to the testicles. The precursor steroids at least pregnenolone has shown to be protective. Not sure what you mean about the DHT/estrogen balance.

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