Gratitude

MateLover87

Hi , wanted to share a one-month follow-up since my original post and your helpful analysis.

Protocol additions since last post:
Following your recommendations, I added:
→ L-Theanine 100mg (afternoon)
→ Taurine 500mg (afternoon)
→ Kelp Iodine 300mcg (3x/week)
→ Ashwagandha KSM-66 (evening — noticeable calming effect, especially after stressful days)
→ B-Complex (daily)
→ Also adjusted: selenium reduced from 200mcg daily to 200mcg 3x/week (couldn't split capsule, so this was the closest approximation to your 100mcg/day suggestion)

Chimarrão (yerba mate): reduced from 0.8L to approximately 2 cuias/day, last one before noon as you suggested. Some days I´m skipping Yerba Mate and drinking Coffe with milk and sugar (one cup a day)

Family vacation without migraine

I took a week-long family trip — historically one of my highest-risk scenarios because I lose control over food quality, sleep schedules, and stress levels. This time:
→ Zero migraines during the entire trip
→ Avoided PUFAs as much as possible but wasn't rigid about it
→ Had a few glasses of red wine on two occasions — historically my strongest and most reliable trigger — and came through completely unaffected

This was genuinely remarkable. Pre-aspirin, one glass of red wine was nearly guaranteed to trigger a severe unilateral migraine within hours. Now, with the full protocol running, I tolerated it without consequence.

The one episode: July 26th
After returning from vacation, I competed in a Crossfit event on July 25th (maximal exertion). Approximately 24 hours later (July 26th), I had a mild episode:
→ Duration: ~10 hours
→ Intensity: mild (manageable)
→ Resolution: aspirin 500mg only — no metamizole (dipyrone) needed
→ Temperature that morning: 36.0°C (vs 36.2°C on July 24th and 36.1°C on July 25th)

This fits the pattern: maximal physical exertion → acute cortisol spike → T4→rT3 shunting → temperature dip → reduced trigeminal threshold → migraine 24-48h later.
I've now confirmed this pattern twice (February training injury, July competition). Regular Crossfit 3x/week seems fine — it's maximal exertion/competition format specifically that crosses the threshold. From now on i will take it easier on crossfit, I like it because of the interaction.

--
Basal temperature — July:
→ July 24: 36.2°C
→ July 25: 36.1°C (competition day)
→ July 26: 36.0°C (migraine day)

Still below the Barnes target of 36.6°C+ consistently. Selenium adjustment and iodine are recent additions — expecting gradual improvement over the coming months.

Broader reflection after 8 months on aspirin + Peat protocol:
For 11 years and 7 doctosrs , I was told to avoid triggers and "drink more water." Nothing touched the underlying mechanism.
Since December 2025:
→ ~95% reduction in migraine frequency
→ Former triggers (wine, chocolate, chimarrão, kombucha) now largely tolerated
→ When episodes do occur: milder, shorter, resolved without heavy medication
→ Zero spontaneous migraines — every episode has an identifiable cause

Thank you again @LucH and this community for the most clinically useful framework I've encountered in over a decade of searching.

LucH

@MateLover87
Good news. Congratulations
You said:
“Had a few glasses of red wine on two occasions — historically my strongest and most reliable trigger.
Now, with the full protocol running, I tolerated it without consequence.”

=> Ok for a glass wine from time to time, when the liver functions well.
Some people can’t tolerate white wine (migraine). Some kinds of red wine contains too much Sulphur and could be a problem.
You have to know that when we drink “alcohol”, any function from the liver is oriented to neutralize ethanol (acetaldehyde), very toxic if you go over the aldehyde dehydrogenase enzyme capacity. This breakdown process changes the cell's balance of molecules (increasing NADH), which stops the liver from burning fat and forces it to store fat instead. Even a standard 5-ounce glass can temporarily alter and fragment brain network communication.
Not a problem if you take this into account and you modulate. Drinking at night alcohol could prevent restorative REM sleep cycles and this hinders the brain's overnight toxin-clearing processes. Only when in difficulties.

Explanation over the liver's sulfur overload capacity
The liver clears toxins using two stages: Phase I (breakdown) and Phase II (packaging for removal).
The Sulfation Bottleneck: One of the main Phase II pathways is sulfation, which relies heavily on sulfur. Wine is loaded with sulfites, and alcohol itself rapidly depletes your liver’s glutathione—the body's master, sulfur-based antioxidant.
The Backlog Trigger: When you drink a glass of wine, you hit the liver with alcohol, sulfites, and histamines simultaneously. If your sulfur pathway enzymes (like SUOX or CBS) are already running at capacity, they overload. This metabolic "traffic jam" causes toxins to recirculate, triggering head pain and systemic inflammation.
PS1: No need to suppress; just know how to adapt.
PS2: I’d use a massage oil with some gaultheria procumbens and lavendula super (5 drops of each 2 or 3x/d) to uncontract muscles after sport. Cure only.
You could learn too how to prepare an oil for massage, instead of using EO, with aloe vera and silicium (G5).

user1

@MateLover87 hi, i suggest go easy on the honey and rapadura, both are depleting, worst combined with milk. if there is ripe fruits available where you are at, it is much better. Higher molybdenum intake can increase body temperature. I find whole milk yogurt with no flavor added, the one i ate these past months, to be great for feeling warm.