Niacinimide for PUFA depletion
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@Galaroc Niacinamide should block lipolysis and assist glucose metabolism, but to my knowledge will not necessarily deplete PUFA stores any faster as it is actively blocking lipolysis.
I wouldn't worry too much about depleting PUFA stores - just let it happen over time.
As for brands, I've heard good things about Purebulk for vitamin powders.
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Thank you - perhaps I didn’t word the initial post well but I’m looking to block the damage that the extra circulating FFAs may cause especially to the brain at night as I am currently studying. I’ll have a further look online for something available here.
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@Galaroc
What about polycosonals? -
@Galaroc Vitamin E mixed tocopherols
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@wagner i am unfamiliar with polysoconals, what are they? I couldn’t make heads or tails of a quick google search
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@Not_James_Bond I’ve drank down all my tocovit and I’m not sure I could find an oral product with as high quality. Would topical work? How important is it to have mixed tocopherols?
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@Galaroc
@Mauritio Here is the thread on the RP forum specifically on it
https://raypeatforum.com/community/threads/the-policosanols-thread.35360/page-18#post-766401 -
I am a bit suspicious about using Niacinimide, it might give temporary relief but if no PUFA gets released into the blood stream then it will also not be used, and if its not gonna be used then it will remain in the body for future you to deal with.
That said I don't know very much about Niacinimide and could be completely misunderstanding how it works.
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@Not_James_Bond Think GNC make vitamin e products available in Guatemala, try and get closest in purity to Tocovit
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@Galaroc been traveling central america a lot the past 2 years and pufa is a huge problem here if you don't cook yourself. Best thing you can do is tocovit or similar mixed vit E or bring your own coconutoil and ask to cook with that, or cook yourself. Also temporarily you can just add a teaspoon of coconutoil after each meal to balance out/displace the pufa you are consuming.
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@laoa I’ve been active with the coco oil but hadn’t given it to my host mom to cook with. I’ll do so in the future. Curious about your vitamin e intake in a high PUFA environment - what kind of dosage? Full blast of tocovit (400iu) ED or EOD?
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@Galaroc I don't do more than 150iu per day and mostly only take it if it was a pufa heavy day. Too much vitE has its own problems and disbalances. I also just don't stress too much about it. It's not forever, you can do better after you had a great time in beautiful Guatemala.
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@Galaroc
It’s supposed to remove and replace PUFA. There is some threads on the old raypeatforum that go into details. -
@Galaroc said in Niacinimide for PUFA depletion:
Hello gentlemen,
I am currently in Guatemala and am living with a host family. Trying to keep peaty and am managing well but PUFA intake is currently non-zero. Have access to aspirin but not K2 and therefor hesitate to blast a lot of it to mitigate the PUFA I’m taking in.
I am interested in niacinimide as an option for mitigation. I have some energin with me and have been using it regularly (I am totally yellow) but I’d like to explore niacinimide specifically.
Anyone have recommendations for brands/dosing/overall protocol for PUFA depletion and management?
Ray Peat preferred smaller doses of niacinamide taken more frequently. I currently take 100mg of niacinamide, 4Xday. Niacinamide is water soluble so it only stays in the body for a couple of hours. I use the purebulk.com niacinamide.
Another thing that Ray Peat suggested taking is some vitamin E. Perhaps somebody can chime in regarding the amount and the timing? I think the goal is to get the vitamin E into your stomach at the same time as the ingested pufa so it can saturate it and make it safer. Sorry, I don't know the amount of vitamin E needed. I suspect a small dose though. Maybe you can find info about it here.
