Glucose loading cures everything?
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@S-Holmes Guys, i know how eating 700grams of carbs a day feels like and i know how it feels to have low stress and lay around after eating lots of honey, but this dextrose coma is paired with blurrier vision and weird coma state, not enjoyable.
2 friends of mine experienced the same. -
@Razvan How much dextrose were you taking and for how long? Did you have a consultation with Dr. Stephens?
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For people that didn't experience the euphoria of sugar (low stress) metabolism that i experienced with stuff like mildronate paired with high carb, this dextrose feeling might make them think that the coma state I was talking about it's just low stress hormones, but if you have experienced both and also have experienced living off adrenaline you clearly know the difference beetween those 3, I might do a blood sugar test after the dextrose to be sure about it.
If your blood sugar is actually doing better i think it's a good sign, because since your body can't handle fructose, glucose metabolism is wrecked and giving the body the easiest and fastest form of glucose without the fructose might help you making you feel better so there is also this possibility, i'm just stating my experience. -
@Razvan So how much dextrose did you take and for how long?
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@S-Holmes 3 days was enough for me, beetween 100 to 300 grams dextrose.
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@Razvan Another possibility is a herxheimer reaction due to the brain healing. One of the first things that happpened to me on dextrose was swelling, and I'm still experiencing that in various parts of my body to a lesser degree. I've never experienced brain healing before so have no point of reference, but I do become sleepy after 3 or so doses of dextrose.
Dr. Stephens told me (email) you will experience a few "bumps" on the protocol. I'm waiting to hear back to schedule a consultation with him. Maybe I'll have a clearer picture of what's happening.
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@evan-hinkle said in Glucose loading cures everything?:
so maybe a quarter tsp or so of added salt per meal
Thanks Evan. I'm not reducing what's going on here to this, but still...
That doesn't sound like very much to me and Jennifer is certainly right about this.
I agree that salted food tastes over-salted after a period of reduced salt intake.
In my experience if I'm lacking in it for a while, I have to slowly ramp up. Or resist a thirst response. And vice versa. If I overdo it. I have to slowly add water. And resist a salt taste. But the latter is very rare for me these days.
I consider Rays "salt to taste" line a cautionary. Because so many people in so many different states would pick up on it. Haidut and others posts on RPF were more useful to me in pushing the boat, so to speak. And finding out that more was better, for me.
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@Insomniac I agree. I'm also following the protocol, but started taking a regular dose every 2 hours, and stopping when I get sleepy. Large random doses may be causing some of the "scary" symptoms a few are reporting.
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@Insomniac 25 grams 4 times a day is the beginning protocol.
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@Insomniac I've also read everything and listened to every podcast I could find. There IS science to back this up so definitely not "faith based."
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@S-Holmes
I've read his book and have been curious about this protocol for a while. But I don't want to gain weight. I already gained using progest-e that seem to not work for me at all. (female 59)
So are you gaining weight or too soon to tell? -
@happyhanneke I don't seem to be. Aside from the initial water retention I seem to be holding.
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@Insomniac I get it. Being cautious is never a bad idea. There are enough of us willing lab rats that it's ok to sit this one out.
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@Insomniac I wonder what the rest of their diet looked like. You can't eat fast food and fries every day (I never do). His 100% cure rate is from people who actually worked with him. It isn't fair to judge him based on anything other than that.
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Hello there.
I've started this a week ago and I'm on 200gr of dextrose per day.
The first night was filled with vivid dreaming of a kind I probably have had to catch up with for a very long time (I dreamt of a prior surgery experience when I had actually been under full anesthesia). However, the 25gr's effects waned after about 3,5-4 hours. Whenever this happened, my pulse rose for no reason (I've been having this for years).
About half an hours after the next dose, the dextrose's effect kicked back in for me and I was calm and off to another 4hrs of deep yet eventful sleeping.About two days in I suddenly had watery diarrhea for half a day.
About a day or two later, I had strong gastrointestinal cramping with a high frequency of almost spastic bowel movements. These were relieved several hours after ingesting psyllium and activated charcoal. I suggest glucose definitely sets some things in motion about restoring forwards peristalsis/motility of the gut and digestive organs.The pure dextrose is really totally different to sucrose or honey. Pure dextrose powder is also so much better than those sour little fruit-flavoured dextrose tabs/lozenges available for purchase. Those are sickening after only a few and had been my only prior experiences with dextrose.
After a couple of days, however, my high pulse remained and it felt as if the dextrose had no more effect. I was also craving something which at first I mistook for being thirsty or hungry:
I need a few mgs of thiamin with each dextrose dose and 1.5grs of potassium chloride. The latter tastes surprisingly extraordinarily good with dextrose.
Both potassium and chloride ions are essential for increasing glucose phosporylation, intracellular (structured) water and volume, and the full-on insulin production and release from pancreatic beta cells. Fructose inhibits all of that.
Sodium is shit. Sodium enhances the cortisol and adrenaline signalling and by this is contrary to the utilization of glucose.
With these, thiamin and potassium chloride, the dextrose dosing has been working for me for the past days without weird cravings and its effects also seem to not wane as quickly as before (heart rate, etc). So I will continue with this regimen and perhaps increase it every week.When I tried 50grs dextrose in the beginning, that was too much as my stomach felt heavy and I had a mild feeling of nausea.
Please give it some thoughts and a try yourselves. I would like to hear others experiences also for the chloride supply without sodium.
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@CrumblingCookie said in Glucose loading cures everything?:
Sodium is shit. Sodium enhances the cortisol and adrenaline signalling and by this is contrary to the utilization of glucose.
Not according to renal function, Ray Peat, and my experience it isn't.
But hopefully we can shed some light on what's separating us.
