Propranolol, agression & autism
-
Since there is a known issue with autistic children and problems of increased aggression and fight-or-flight susceptibility during puberty, my question is: does anyone have personal experience with propranolol?
It's a well-known, old beta-blocker. According to literature , it is one of the few medicines which directly attenuates aggressive outbursts and lowers the fight-or-flight response. Also used "off-label" for above stated issues.
A concern is bradycardia and hypotension in children. Since only available dosage is 40 mg. Tablet can not be divided.
I know cyproheptadine is useful for lowering serotonin, but it is not available in our region, nor in neighboring countries.
Personal experiences are more welcome than PubMed linking.
Kind regards
-
alldaychemist does not ship cyproheptadine to your country? they have Best cypro for extremely cheap.
https://www.alldaychemist.com/ciplactin-4mg.html -
No experience but it ought to be of interest to everyone.
@Uroš said in Propranolol, agression & autism:
A concern is bradycardia and hypotension in children.
Interesting. Maybe Wakefield was right about the vagus nerve, or a stop on it.
"Propranolol acts by blocking vasodilatory beta 1 receptors and reducing cardiac output. A major side effect of vasopressin therapy is impaired cardiac performance secondary to coronary vasoconstriction and increased work against high arterial pressure."
@Uroš said in Propranolol, agression & autism:
Personal experiences are more welcome than PubMed linking.
Blogs ok ✓
https://www.epiphanyasd.com/2020/02/thirst-too-much-or-too-little.html?m=1
-
@ThinPicking thanks.
-
T ThinPicking referenced this topic on
