How does alcohol and thiamine "depletion" work in practice exactly?

Ray Peat Fanboy

Lets say you have a drinking session one night, so then the next day is all your liver thiamine stores completly gone suddenly?

And what if you take 500 mg of Thiamine HCL the next day after a drinking session? Does your thiamine stores return to normal then?

LucH

@Ray-Peat-Fanboy said in How does alcohol and thiamine "depletion" work in practice exactly?:

How does alcohol and thiamine "depletion" work in practice exactly?

Ability to absorb thiamine is progressively lost due to inflammation of stomach lining and lost of transport capacity.
"Heavy alcohol use causes inflammation of the stomach lining and digestive tract, which reduces the body's ability to absorb vitamins."
Note: Heavy = repetitive use, more than what the liver can handle.
Before night sleep 1/4 tsp L-glutamine powder could help to rebuild leaky gut.

at day light (2x/day)
=> glutamine = nutrient for stomach lining.