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Some quick health finds #2

Bioenergetics Discussion
surgery constipation staph diabetes anemia
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  • C
    cs3000
    last edited by cs3000 Jan 10, 2025, 1:17 PM Nov 28, 2024, 12:02 PM

    continued from #1 https://cs3001.substack.com/p/a-bunch-of-quick-health-and-biology

    1. Surgery causes a big acute drop in pyruvate dehydrogenase activity through depleting thiamine (needed to use carbs fully, converting pyruvate from carbs to acetyl-coa & co2)
      https://pmc.ncbi.nlm.nih.gov/articles/PMC4472607/

    takeaway: need a thiamine boost after surgery

    Measurements of PDH activity and quantity and thiamine were obtained prior to surgery, at the completion of surgery, and 6 hours post-surgery. Study subjects had a mean 41.7 % (SD: 27.7) reduction in PDH activity after surgery and a mean 32.0% (SD: 31.4) reduction 6 hours after surgery (p < 0.001). Eight patients were thiamine deficient (≤ 7 nmol/L) after surgery compared to none prior to surgery


    1. Monolaurin protects well against staph infection https://pubmed.ncbi.nlm.nih.gov/20021093/ http://visordocs.sic.gov.co/documentos/Docs019/docs20/2014/2014006996OF/2014006996OF0000000003.PDF?713
      killed all 14 control mice within 1 week. 50% survived for 30 days when given monolaurin orally.
      3.2mg monolaurin given to mice weighing 15 to 20g so 160g/kg = shown effective at 800mg-1g human dose. (higher dose might not be better).

    Human milk contains monolaurin around 3 mg/mL. When the monolaurin is eliminated, the anti-inflammatory and antimicrobial activity is low

    , (also can clear some parasites responsible for stomach bugs,
    BUT not suitable for long term use,
    8 weeks of ~200mg caused metabolic dysfunction & inflammation in mice, because its only effective against gram positive bacteria which let gram negative bacteria grow too much)

    1. Constipation -
      daily physical movement (walking) plays a big role in bowel movements. inactivity for 2 weeks = bowel movements went from average of 9.5 a week -> 4.5 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3748072/

    Our results showed a new onset of functional constipation at the end of 35-days of bed rest in 60% of healthy volunteers as diagnosed by Rome III criteria


    1. More https://cs3001.substack.com/p/some-quick-health-finds-2

    "world," as a source of new perceptions
    more https://substack.com/@cs3001

    "Self-organizing systems decay only if they have assimilated inertia and — with a little support of the right kind— the centers of degeneration can become centers of regeneration"

    I 1 Reply Last reply Nov 28, 2024, 12:11 PM Reply Quote 0
    • I
      Insomniac @cs3000
      last edited by Nov 28, 2024, 12:11 PM

      @cs3000 said in Some quick health finds #2:

      More https://cs3001.substack.com/p/some-quick-health-finds-2

      excellent finds. appreciated

      1 Reply Last reply Reply Quote 0
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